Cyclofenil

01/01/2000 - "Cyclofenil for Raynaud's phenomenon in progressive systemic sclerosis."
10/01/1983 - "Treatment of progressive systemic sclerosis (PSS) with cyclofenil."
01/01/1981 - "Cyclofenil was evaluated versus placebo in the treatment of progressive systemic sclerosis (PSS, scleroderma) in a 2 x 6-month double-blind crossover study. "
01/01/1981 - "Cyclofenil versus placebo in progressive systemic sclerosis. "
01/01/1980 - "Results are presented from an open treatment of 29 patients suffering from progressive systemic sclerosis (PSS) with cyclofenil, an oestrogenlike non-steroid compound with very low oestrogenicity, which was recently claimed to be effective in this disorder. "

04/01/1975 - "[Ondogyne in the treatment of ovarian sterility]."
09/01/1983 - "Bromocryptine-cyclofenil associated therapy: an effective and safe mode of treatment of female normoprolactinemic infertility."

05/01/2010 - "These results demonstrate that these radiolabeled cyclofenil derivatives may be considered as potential breast cancer imaging agents."
04/01/2008 - "Synthesis of new carbon-11 labeled cyclofenil derivatives for PET imaging of breast cancer estrogen receptors."
04/20/2006 - "Fluorine-substituted cyclofenil derivatives as estrogen receptor ligands: synthesis and structure-affinity relationship study of potential positron emission tomography agents for imaging estrogen receptors in breast cancer."
04/01/2008 - "Carbon-11 labeled cyclofenil derivatives, [(11)C]methyl-2-{4-[bis(4-hydroxyphenyl)methylene]cyclohexyl}acetate ([(11)C]16a), [(11)C]methyl-4-[bis(4-hydroxyphenyl)methylene]cyclohexanecarboxylate ([(11)C]16b), [(11)C]methyl-2-{3-[bis(4-hydroxyphenyl)methylene]cyclohexyl}acetate ([(11)C]18a), and [(11)C]methyl-3-[bis(4-hydroxyphenyl)methylene]cyclohexanecarboxylate ([(11)C]18b), have been synthesized as new potential PET agents for imaging breast cancer estrogen receptors. "
04/20/2006 - "In a search for estrogen receptor (ER) ligands to be radiolabeled with fluorine-18 for imaging of ER-positive breast tumors with positron emission tomography (PET), we investigated cyclofenil analogues substituted at the C3 or C4 position of the cyclohexyl group. "

01/01/1992 - "In a two-year prospective therapeutic trial 13 patients with systemic sclerosis (SSc) were treated with penicillamine, 9 with cyclofenil, and 7 with neither. "
01/01/1992 - "Long-term evaluation of penicillamine or cyclofenil in systemic sclerosis. "

02/01/1992 - "Acute hepatitis induced by cyclofenil: a case report."
04/01/1991 - "We report a case of acute hepatitis due to cyclofenil retrospectively diagnosed during acute viral hepatitis (HBV). "
04/01/1991 - "[Cyclofenil-induced acute hepatitis. "
11/01/1986 - "[A 3d case of hepatitis caused by cyclofenil in Lyons]."
02/01/1992 - "The case of a 47-year old woman suffering from acute hepatitis caused by cyclofenil, a drug proposed for the treatment of anovulation and scleroderma, is presented. "