Cyclandelate

02/01/2001 - "In conclusion, cyclandelate was not superior to placebo in the prophylaxis of migraine with regard to parameters usually used in migraine prophylaxis trials."
02/01/2001 - "Neither the primary study endpoint (reduction of migraine days from baseline to the last 28 days) nor most of the secondary endpoints (reduction in the number of migraine attacks, severity or duration of attacks, frequency of autonomic disturbances, medication for treatment of attacks) showed a difference between cyclandelate and placebo. "
02/01/2001 - "Cyclandelate in the prophylaxis of migraine: a placebo-controlled study."
01/01/1998 - "Clinical efficacy and central mechanisms of cyclandelate in migraine: a double-blind placebo-controlled study."
09/01/1994 - "If the results yielded by the present study are confirmed, cyclandelate should be classified as a drug of first choice for migraine prophylaxis."

01/01/1987 - "These results indicate that cyclandelate may be useful in the management of vertigo of circulatory origin in general practice."
01/01/1987 - "A multicentre study with 622 patients has been undertaken to evaluate the efficacy of cyclandelate 1600 mg daily in the treatment of vertigo of circulatory origin in general practice. "
01/01/1987 - "During the 3-month period of treatment with cyclandelate, the average global score of vertigo (0-10) decreased from 5.57 to 2.12 and the average scores of frequency, severity and duration of vertigo (0-4) decreased from 2.53, 2.55 and 2.26 to 0.98, 0.89 and 0.84, respectively. "
01/01/1987 - "Cyclandelate in the treatment of vertigo of circulatory origin. "
01/01/1987 - "Thus, when used in the setting of general practice, cyclandelate seems to be a safe and apparently effective treatment for patients with symptoms of vertigo, tinnitus and visual disturbances attributable to chronic cerebrovascular insufficiency."

10/01/1984 - "Chronic cerebrovascular disorders: a clinical study with cyclandelate."
01/01/1984 - "Clinical effects of Cyclospasmol in patients affected by chronic cerebrovascular disorders."
10/01/1966 - "Effect of cyclandelate on cerebral cortex perfusion-rates in cerebrovascular disease."
01/01/1987 - "Perceived efficacy of cyclandelate in the treatment of cochleovestibular and retinal disturbances related to cerebrovascular insufficiency. "
01/01/1982 - "[Efficacy of an etofylline-cyclandelate combination in age-dependent cerebrovascular insufficiency]."

03/01/1998 - "Recent personal communications regarding cyclandelate's effectiveness in treating tinnitus prompted this study. "
03/01/1998 - "Early nonrandomized and uncontrolled studies suggest that cyclandelate is efficacious in treating tinnitus. "
03/01/1998 - "Cyclandelate in the management of tinnitus: a randomized, placebo-controlled study."
03/01/1998 - "Four patients in the cyclandelate group and three in the placebo group reported a subjective reduction in the loudness of their tinnitus. "
01/01/1987 - "Thus, when used in the setting of general practice, cyclandelate seems to be a safe and apparently effective treatment for patients with symptoms of vertigo, tinnitus and visual disturbances attributable to chronic cerebrovascular insufficiency."

05/01/2000 - "A 24-week, double-blind, multi-center, randomised parallel group study compared the efficacy and safety of 800 mg bid cyclandelate with placebo in patients with mild to moderate dementia of primary degenerative or vascular origin. "
09/01/1975 - "Six psychological tests, which reflect various aspects of higher cortical ability, were used to evaluate the effect of cyclandelate on the dementia. "
09/01/1975 - "Effect of cyclandelate on dementia."
05/01/2000 - "Cyclandelate in the treatment of patients with mild to moderate primary degenerative dementia of the Alzheimer type or vascular dementia: experience from a placebo controlled multi-center study."
01/01/1987 - "At 90 days, significant improvements were observed in patients given cyclandelate in measurements of P100 latency in the left eye, neurological impairment, dementia scores, ischaemia scores, Gottfries mental deterioration scale, Hamilton depression scores, short term visual memory, long term memory, Bender-Gestalt test and Koh's blocks test. "