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Cushing Syndrome

A condition caused by prolonged exposure to excess levels of cortisol (HYDROCORTISONE) or other GLUCOCORTICOIDS from endogenous or exogenous sources. It is characterized by upper body OBESITY; OSTEOPOROSIS; HYPERTENSION; DIABETES MELLITUS; HIRSUTISM; AMENORRHEA; and excess body fluid. Endogenous Cushing syndrome or spontaneous hypercortisolism is divided into two groups, those due to an excess of ADRENOCORTICOTROPIN and those that are ACTH-independent.
Also Known As:
Cushing's Syndrome; Syndrome, Cushing's; Syndrome, Cushing; Hypercortisolism
Networked: 6897 relevant articles (414 outcomes, 468 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pituitary ACTH Hypersecretion
2. Cushing Syndrome
3. Neoplasms (Cancer)
4. Adenoma (Adenomas)
5. Hypertension (High Blood Pressure)

Experts

1. Stratakis, Constantine A: 72 articles (03/2022 - 08/2003)
2. Bertherat, Jérôme: 48 articles (08/2022 - 05/2002)
3. Reincke, Martin: 48 articles (07/2022 - 11/2006)
4. Lacroix, André: 40 articles (06/2022 - 01/2002)
5. Beuschlein, Felix: 38 articles (07/2022 - 03/2002)
6. Nieman, Lynnette K: 36 articles (09/2022 - 07/2002)
7. Pivonello, Rosario: 36 articles (01/2022 - 05/2003)
8. Boscaro, Marco: 35 articles (11/2020 - 01/2002)
9. Scaroni, Carla: 34 articles (01/2022 - 02/2006)
10. Sasano, Hironobu: 32 articles (07/2021 - 07/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cushing Syndrome:
1. Adrenocorticotropic Hormone (ACTH)FDA Link
2. Hydrocortisone (Cortisol)FDA LinkGeneric
3. Dexamethasone (Maxidex)FDA LinkGeneric
4. GlucocorticoidsIBA
5. Mifepristone (RU 486)FDA Link
6. Ketoconazole (Nizoral)FDA LinkGeneric
7. MetyraponeFDA Link
8. Mitotane (Lysodren)FDA Link
9. trilostaneFDA Link
10. Adrenal Cortex Hormones (Corticosteroids)IBA

Therapies and Procedures

1. Adrenalectomy
2. Therapeutics
3. Radiotherapy
4. Aftercare (After-Treatment)
5. Hypophysectomy