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Crigler-Najjar Syndrome (Syndrome, Crigler-Najjar)

A familial form of congenital hyperbilirubinemia transmitted as an autosomal recessive trait. It is characterized by icterus and brain damage caused by a glucuronyl transferase deficiency in the liver and faulty bilirubin conjugation.
Also Known As:
Syndrome, Crigler-Najjar; Crigler-Najar Syndrome; Crigler Najar Syndrome; Crigler Najjar Syndrome; Syndrome, Crigler-Najar
Networked: 172 relevant articles (4 outcomes, 10 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Hyperbilirubinemia
2. Ornithine Carbamoyltransferase Deficiency Disease
3. Gilbert Disease
4. Jaundice
5. Neonatal Hyperbilirubinemia

Experts

1. Fox, Ira J: 4 articles (07/2015 - 06/2003)
2. Brunetti-Pierri, Nicola: 4 articles (06/2014 - 04/2011)
3. Nilyanimit, P: 3 articles (01/2015 - 01/2013)
4. Poovorawan, Y: 3 articles (01/2015 - 01/2013)
5. Pastore, Nunzia: 3 articles (06/2014 - 10/2012)
6. Labrune, Philippe: 3 articles (06/2014 - 10/2002)
7. Ng, Philip: 3 articles (10/2013 - 03/2005)
8. Maruo, Yoshihiro: 3 articles (03/2011 - 01/2002)
9. Jia, Zhen: 3 articles (11/2005 - 12/2004)
10. Dankó, István: 3 articles (11/2005 - 12/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Crigler-Najjar Syndrome:
1. BilirubinIBA
2. Factor VII (Proconvertin)IBA
3. progressive familial intrahepatic 1 CholestasisIBA
4. 4-O-carboxymethylascochlorinIBA
5. Uridine Diphosphate (UDP)IBA
6. TransferasesIBA
7. Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA
8. GlucuronidesIBA
9. Nonsense Codon (Nonsense Mutation)IBA
10. Complementary DNA (cDNA)IBA

Therapies and Procedures

1. Liver Transplantation
2. Homologous Transplantation (Allograft)
3. Injections
4. Transplantation (Transplant Recipients)
5. Transplants (Transplant)