|5.||Astrocytoma (Pilocytic Astrocytoma)
|1.||You, Chao: 12 articles (09/2015 - 01/2006)|
|2.||Xu, Jianguo: 10 articles (09/2015 - 01/2006)|
|3.||Müller, Hermann L: 9 articles (09/2015 - 08/2002)|
|4.||Buslei, Rolf: 9 articles (01/2014 - 06/2005)|
|5.||Fahlbusch, Rudolf: 9 articles (01/2014 - 06/2005)|
|6.||Buchfelder, Michael: 8 articles (01/2014 - 07/2005)|
|7.||Gebhardt, Ursel: 7 articles (09/2015 - 07/2004)|
|8.||Anand, Vijay K: 7 articles (07/2015 - 03/2007)|
|9.||Schwartz, Theodore H: 7 articles (07/2015 - 03/2007)|
|10.||Kelly, Daniel F: 7 articles (01/2015 - 02/2003)|
|1.||Interferon-alpha (Interferon Alfa)FDA Link
08/01/2005 - "This study analyzed the intratumoral activity of interferon alpha (IFN-alpha) in the treatment of cystic craniopharyngiomas. "
02/01/2011 - "To assess whether the cystic craniopharyngiomas can be controlled with the use of intratumoral applications of interferon alpha. "
06/01/2007 - "The aim of this study was to analyze the long-term results of the surgical management of craniopharyngioma in children by reviewing a series of patients consecutively treated in a single institution, and to assess the efficacy of intratumoral chemotherapy with interferon-alpha. "
04/01/2010 - "The authors assessed the efficacy of intratumoral interferon-alpha (IFNalpha)-based chemotherapy in pediatric patients with cystic craniopharyngiomas. "
04/01/2010 - "Craniopharyngiomas: intratumoral chemotherapy with interferon-alpha: a multicenter preliminary study with 60 cases."
|2.||Growth Hormone (Somatotropin)IBA
01/01/2012 - "[Pathological daytime sleepiness in an 11-year old girl receiving growth hormone treatment previously cured from craniopharyngioma]."
01/01/1998 - "We studied short- and long-term responses to growth hormone (GH) treatment and adverse medical events (AE) in 488 patients with craniopharyngioma who were entered into the Kabi International Growth Study (KIGS). "
10/01/1996 - "Effect of growth hormone treatment in children with craniopharyngioma with reference to the KIGS (Kabi International Growth Study) database."
05/01/2011 - "[Height and weight development in an adolescent with complete growth hormone deficiency secondary to a craniopharyngioma]."
01/01/2010 - "Controversies surround various treatment variables for patients with childhood craniopharyngioma such as growth hormone (GH) replacement, which some believe can exacerbate recurrence/progression. "
12/01/2012 - "Previous studies of systemic and intralesional administration of nonpegylated interferon have shown efficacy against craniopharyngioma. "
12/01/2010 - "Additional studies will be necessary to establish the role of these molecules in the pathogenesis of craniopharyngioma, and further investigations will be necessary to confirm the efficacy of the antitumoral activity of interferon-α."
01/01/2016 - "Visual Field Loss in a Case of Recurrent Cystic Craniopharyngioma During Concomitant Treatment With Pegylated Interferon α-2b."
09/01/2015 - "Interferon-α (IFN-α) has been gaining popularity as an intracystic treatment for craniopharyngioma because of its efficacy and supposed benign neurotoxicity profile. "
09/01/2015 - "Intracystic interferon-α treatment leads to neurotoxicity in craniopharyngioma: case report."
|4.||Bleomycin (Blenoxane)FDA LinkGeneric
04/01/2012 - "Intracystic bleomycin (ICB) administration is known to be effective in the treatment of cystic craniopharyngiomas (CRPs) and rarely causes serious complications. "
01/01/2014 - "Since we identified no RCTs, quasi-randomised trials or CCTs of the treatment of cystic craniopharyngiomas in children in which only the use of intracystic bleomycin differed between the treatment groups, no definitive conclusions could be made about the effects of intracystic bleomycin in these patients. "
01/01/2014 - "Randomised controlled trials (RCTs), quasi-randomised trials or controlled clinical trials (CCTs) comparing intracystic bleomycin and other treatments for cystic craniopharyngiomas in children (from birth to 18 years). "
01/01/2012 - "Since no RCTs, quasi-randomised trials or CCTs in which only the use of intracystic bleomycin differed between the treatment groups in the treatment of cystic craniopharyngiomas in children, no definitive conclusions could be made about the effects of intracystic bleomycin in these patients. "
01/01/2012 - "Randomised controlled trials (RCTs) quasi-randomised trials or controlled clinical trials (CCTs) comparing intracystic bleomycin and other treatments for cystic craniopharyngiomas in children (from birth to 18 years). "
03/01/1996 - "Stereotactic intratumour irradiation with instillation of nuclide colloid is effective in the patients with craniopharyngiomas. "
05/01/2010 - "The aim of the study was to evaluate the effect of phosphorus-32 colloid ([(32)P]) intracavitary irradiation on the treatment of patients with cystic craniopharyngiomas. "
08/01/2007 - "Long-term results and late complications after intracavitary yttrium-90 colloid irradiation of recurrent cystic craniopharyngiomas."
12/15/1997 - "The authors analyzed long-term follow-up data to assess the value of intracavitary irradiation with stereotactically implanted beta-emitting radioisotope (90)Y-silicate colloid for the treatment of craniopharyngiomas. "
12/15/1997 - "Treatment of cystic craniopharyngiomas with yttrium-90 colloid solution."
09/01/2015 - "Fifty-one patients (2.1-19.3 years of age) with craniopharyngioma underwent surgery and proton therapy in a prospective therapeutic trial. "
09/01/2015 - "The purpose of this study was to determine radiation dose effect on the structural integrity of cerebral white matter in craniopharyngioma patients receiving surgery and proton therapy. "
09/01/2015 - "DTI data suggest that mild radiation dose effects occur in patients with craniopharyngioma receiving surgery and proton therapy. "
09/01/2015 - "Effects of Surgery and Proton Therapy on Cerebral White Matter of Craniopharyngioma Patients."
06/01/2015 - "Currently there is no clear evidence that proton beam therapy will improve survival or reduce morbidity for children with craniopharyngioma. "
|7.||Biological Markers (Surrogate Marker)IBA
01/01/2003 - "The goal of this study was to determine the efficacy of using selected biological markers to distinguish between recurring and nonrecurring craniopharyngiomas. "
04/01/2005 - "The purpose of this study was to identify biological markers that may be involved in the adhesiveness of craniopharyngiomas to optical chiasms and/or pituitary stalks. "
08/01/2007 - "Biological markers are under investigation and this will increase our knowledge on craniopharyngioma. "
12/01/2003 - "While almost always benign, craniopharyngiomas exhibit a high propensity to recur postsurgically and biological markers are therefore needed to predict their recurrence. "
06/01/2007 - "A recurrent craniopharyngioma illustrates the potential usefulness of urinary matrix metalloproteinases as noninvasive biomarkers: case report."
|8.||tranilast (N 5')IBA
01/01/2014 - "Patients with progression of craniopharyngioma (n=5) when compared to patients without progression of craniopharyngioma (n=14) were significantly younger at the time of surgery, had less visual deterioration before surgery and had higher rates of not changed vision after surgery. "
03/01/1998 - "Eight patients with cystic craniopharyngiomas had comparable CT or MR studies before and after either external irradiation of the cyst (n = 5) or 32P instillation into the cyst (n = 3). "
07/01/2015 - "Etiologies of CSF leak were iatrogenic after endoscopic sinus surgery (n = 5, 55.6%) or revision craniopharyngioma resection (n = 1, 11.1%), spontaneous (n = 1, 11.1%), anterior skull base meningocele with CSF leak (n = 1, 11.1%), and posttraumatic (n = 1, 11.1%). "
09/01/1991 - "In a review of 131 sellar or juxtasellar abnormalities, 76% were common lesions with distinctive features that helped establish their diagnosis: macroadenoma (n = 51), microadenoma (n = 20), meningioma (n = 14), craniopharyngioma (n = 10), and aneurysm (n = 5). "
11/25/2014 - "The procedures included biopsy of stereotactic guidance (n = 6), stereotactic aspiration and drainage for brain abscess (n = 4), stereotactic aspiration and intracavitary irradiation with (32)P for mixed solid and cystic craniopharyngiomas (n = 3) and stereotactic hematoma evacuation (n = 5). "
|9.||papillary Thyroid cancerIBA
10/01/2015 - "Recent studies have shown that other papillary tumors harbor BRAF-V600E mutations, namely papillary thyroid carcinoma and papillary craniopharyngioma, the latter of which is a midline central nervous system papillary tumor like PTPR. "
05/01/1997 - "Both meningiomas were positive for SR scans: positive results were also obtained for the high grade astrocytoma and the craniopharyngioma: Two out of 6 patients with papillary thyroid cancer showed a marked radiotracer accumulation. "
11/01/1986 - "A case is presented in which a histologically proven prolactin secreting pituitary macroadenoma was associated with a large suprasellar craniopharyngioma. "
09/01/1985 - "Seventy-one percent (32) of the 45 patients with craniopharyngiomas or tumours with negative immunostaining for prolactin, had raised pretreatment serum prolactin levels (above 360 mU/l) although this was usually only slightly elevated; the levels exceeded 2500 mU/l in six (13%) of them (two craniopharyngiomas, four pituitary tumours) but in none did the levels exceed 6000 mU/l. "
09/01/1985 - "There was no significant difference in pretreatment serum prolactin levels between 11 patients with craniopharyngiomas and 34 patients with pituitary macroadenomas showing no prolactin immunostaining. "
11/01/1983 - "In all normal children and 6/7 patients with IGHD, hpGRF 1-40 at all doses used induced a clear and sustained lowering of plasma prolactin levels; this effect was lacking in the patient with craniopharyngioma. "
01/01/1982 - "Nevertheless, for the peculiar diencephalic control of the prolactin (PRL) pituitary secretion, different endocrinological pictures can be observed, related to the different degree of pituitary-hypothalamic compression from the craniopharyngioma. "
04/16/1988 - "Similarly, in an 8-year old girl reoperated upon for severe recurrent suprasellar craniopharyngioma 3 years after the initial excision, post-operative radiotherapy (5,000 rads) produced excellent remission which persists after 19 years. "
01/01/1988 - "Radiotherapy after limited resection of craniopharyngiomas has been advocated by some investigators while others contend radical resections by means of advanced surgical techniques afford better outcome of patients. "
12/01/2011 - "The therapeutic efficacy of fractionated radiotherapy and gamma-knife radiosurgery for craniopharyngiomas."
02/01/2006 - "Subtotal removal followed by early fractionated radiotherapy can be an effective treatment for huge craniopharyngiomas. "
09/01/2003 - "By analyzing these data while considering all available information on the efficacy of surgery and radiotherapy, the proliferation potential of craniopharyngiomas, when evaluated by MIB-1, has no role in the outcome. "
|2.||Drug Therapy (Chemotherapy)
04/01/2010 - "This has been the largest documented series of intratumoral chemotherapy using INFalpha for the control of cystic craniopharyngiomas. "
09/01/2007 - "Twenty-one patients with cystic craniopharyngiomas treated at the Pediatric Oncology Institute (IOP/GRAACC) of Federal University of São Paulo were submitted to intracystic chemotherapy with IFN-alpha. "
04/01/2006 - "Does chemotherapy have a role in the management of craniopharyngioma?"
10/01/2004 - "The remarkable response of this malignant tumour ex-craniopharyngioma to cis-platin based chemotherapy, together with other midline tumour characteristics of craniopharyngioma, raise the question as to whether craniopharyngioma should any longer be separately considered from suprasellar germ cell tumour. "
10/01/2004 - "Dramatic response of malignant craniopharyngioma to cis-platin-based chemotherapy. "
03/01/2006 - "In this study, we assessed QoL in 29 adult patients in remission during long-term follow-up after treatment for craniopharyngioma. "
01/01/1999 - "The goal of our study is to analyse retrospectively the manifestations of craniopharyngioma and their prognosis after treatment in function of the age."
03/01/1987 - "[Pituitary function in craniopharyngioma: study of 8 cases before and after treatment]."
02/01/2012 - "Results after treatment of craniopharyngiomas: further experiences with 73 patients since 1997."
02/01/2011 - "Endocrinologic, neurologic, and visual morbidity after treatment for craniopharyngioma."
11/01/2010 - "3. Trans-rostrum corporis callosi-lamina terminalis approach TRCLA revealed to be less invasive and helpful for removal of a small recurrent craniopharyngioma located between the chiasma opticum and the AcomA complex with the use of a small craniotomy, avoiding previous craniotomy routes, both pterional and subfrontal, for fear of structural adhesion (Fig. "
10/01/2009 - "In this study, the authors evaluated the efficacy and safety of modified orbitozygomatic craniotomy for resection of craniopharyngioma in children. "
01/01/2015 - "A 36-year-old male had five craniotomies, five transsphenoidal surgeries, and two radiation treatments until 31 years of age after diagnosis of craniopharyngioma at 12 years of age. "
01/01/2014 - "This iatrogenic injury resulted from two prior craniotomies for excision of craniopharyngioma and its recurrence. "
05/01/2011 - "She presented with a sellar craniopharyngioma at the age of 4 years and underwent a right subfrontal craniotomy. "
05/01/2015 - "The authors evaluated the effects of treating 20 patients with giant posterior fossa cystic craniopharyngiomas using phosphorus-32 (P-32) interstitial radiotherapy at their hospital. "
05/01/2015 - "Interstitial radiotherapy using phosphorus-32 for giant posterior fossa cystic craniopharyngiomas."
07/01/2013 - "Combination treatment with Gamma Knife radiosurgery and stereotactic intracavitary brachytherapy is highly effective and safety in the treatment of mixed cystic and solid craniopharyngiomas."
07/01/2013 - "Sixty-seven consecutive patients with mixed cystic and solid craniopharyngioma treated by Gamma Knife radiosurgery combined with stereotactic brachytherapy from October 1996 to December 2005 were selected for retrospective analysis. "
07/01/2013 - "To evaluate the long-term results of combination treatment with Gamma Knife radiosurgery and stereotactic intracavitary brachytherapy for mixed cystic and solid craniopharyngiomas. "