|4.||Atherosclerotic Plaque (Atheroma)
|5.||Coronary Vasospasm (Coronary Artery Vasospasm)
|1.||Virmani, Renu: 6 articles (02/2007 - 10/2002)|
|2.||Mikkelsson, J: 4 articles (08/2001 - 07/2000)|
|3.||Karhunen, P J: 4 articles (08/2001 - 07/2000)|
|4.||Perola, M: 4 articles (08/2001 - 07/2000)|
|5.||Penttilä, A: 4 articles (08/2001 - 07/2000)|
|6.||Spuentrup, Elmar: 3 articles (01/2006 - 09/2004)|
|7.||Sakuma, Tadamichi: 3 articles (06/2005 - 01/2003)|
|8.||Kaul, Sanjiv: 3 articles (06/2005 - 01/2003)|
|9.||Mikkelsson, Jussi: 3 articles (05/2005 - 11/2002)|
|10.||Perola, Markus: 3 articles (05/2005 - 11/2002)|
|1.||Tissue Plasminogen Activator (Alteplase)FDA Link
10/01/1991 - "The use of tissue plasminogen activator gave good results in the treatment of acute coronary thrombosis. "
09/01/1997 - "An Alu-repeat polymorphism in the gene coding for tissue-type plasminogen activator has been described recently, and it has been hypothesized that this polymorphism may predict risk of coronary thrombosis. "
05/01/1994 - "Comparative effects of anti-platelet agents as adjuncts to tissue plasminogen activator in a dog model of occlusive coronary thrombosis."
07/01/1992 - "Sustained reflow in dogs with coronary thrombosis with K2P, a novel mutant of tissue-plasminogen activator."
07/01/1989 - "To address this hypothesis, we examined the role of TXA2 in modulating the response to intravenous tissue-type plasminogen activator (t-PA) in a chronic canine model of coronary thrombosis. "
|2.||Aspirin (Acetylsalicylic Acid)FDA LinkGeneric
11/01/1989 - "At present, aspirin is virtually the only drug that has proved to be effective in all cases where the risk of coronary thrombosis was very high. "
06/14/1983 - "Costly clinical trials have provided evidence in favor of aspirin preventing thrombotic events affecting the brain; its effectiveness against coronary thrombosis is not yet definitely established. "
01/01/1977 - "This trial is based upon several previously published studies which suggest that aspirin may be valuable iprevention of coronary thrombosis. "
12/01/2013 - "Aspirin may be considered to prevent coronary thrombosis. "
02/01/2013 - "Aspirin prevents coronary thrombosis and is used extensively in cardiovascular prophylaxis. "
|3.||Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA
11/22/2006 - "Antiplatelet drugs and intraoperative haemorrhage Current literature demonstrates that there is less risk involved in maintaining anti-aggregant therapy (which might imply to transfuse more the patients), than in stopping it, which then increases dangerously the risk of coronary thrombosis. "
06/01/2003 - "Platelet aggregation inhibitors in prevention and treatment of coronary thrombosis."
07/01/2013 - "On the other hand, it has been shown that the risk of surgical bleeding, if antiplatelet drugs are continued, is lower than that of coronary thrombosis if they are withdrawn. "
06/01/2010 - "The risk of coronary thrombosis when antiplatelet agents are withdrawn before surgery is generally higher than the risk of surgical hemorrhage when antiplatelet agents are maintained. "
08/01/2009 - "It has also been shown that the risk of surgical bleeding, if antiplatelet drugs are continued, is lower than that of coronary thrombosis if they are withdrawn. "
|4.||eptifibatide (Integrilin)FDA Link
01/01/2004 - "The safety and clinical efficacy of eptifibatide in patients undergoing percutaneous coronary intervention (PCI) was first evaluated in the Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis (IMPACT) trial. "
11/01/2001 - "Effect of eptifibatide on angiographic complications during percutaneous coronary intervention in the IMPACT--(Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis) II Trial."
02/15/2000 - "Patients enrolled in the Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis-II (IMPACT-II) trial were analyzed. "
05/17/1997 - "Randomised placebo-controlled trial of effect of eptifibatide on complications of percutaneous coronary intervention: IMPACT-II. Integrilin to Minimise Platelet Aggregation and Coronary Thrombosis-II."
11/01/1996 - "An eight-page questionnaire was completed by 70 hospitals participating in the study titled Integrelin to Manage Platelet Aggregation to Prevent Coronary Thrombosis (IMPACT II). "
06/01/2013 - "The glycoprotein IIb/IIIa receptor is the final common pathway of platelet aggregation, regardless of the agonist, and thus represents an ideal therapeutic target for blocking coronary thrombosis. "
12/01/2011 - "Role of platelet glycoprotein receptor IIIa PI(A2) and traditional risk factors in the etiology of coronary thrombosis."
01/01/2004 - "The PlA polymorphism (Leu33Pro) of the platelet glycoprotein (GP) IIIa gene has been suggested to play an important role in coronary thrombosis. "
12/22/1998 - "Platelet-derived 12-hydroxyeicosatetraenoic acid plays an important role in mediating canine coronary thrombosis by regulating platelet glycoprotein IIb/IIIa activation."
09/01/1998 - "Recently, a strong association between the P1A2 polymorphism of the glycoprotein IIIa gene and acute coronary thrombosis has been reported. "
|6.||Epinephrine (Adrenaline)FDA LinkGeneric
03/01/2009 - "In positive control studies, epinephrine increased platelet responsiveness and accelerated canine coronary thrombosis. "
01/01/1994 - "The present study demonstrated that acutely raising plasma [K] inhibited coronary thrombosis in dogs and also blocked the potentiating effect of epinephrine on coronary thrombosis. "
01/01/1994 - "The present study was designed to investigate the effect of raising plasma [K] and its interaction with epinephrine infusion on coronary thrombosis. "
01/01/1994 - "Many studies have shown that epinephrine has a stimulatory effect on coronary thrombosis; however, little information is available concerning the effect of raising plasma [K] on coronary thrombosis. "
02/15/1995 - "Therefore, the present study was designed to investigate the effect of norepinephrine and its interaction with epinephrine on coronary thrombosis. "
09/10/2013 - "The need to reduce future cardiovascular events has led to the development of novel therapies to prevent coronary thrombosis, targeting thrombin-mediated pathways. "
11/15/1996 - "Thrombin plays an important role in the pathogenesis of acute coronary thrombosis. "
09/12/1996 - "Thrombin has a pivotal role in the pathogenesis of acute coronary thrombosis. "
06/01/1993 - "In protocol I coronary thrombosis was induced by endothelial injury and injection of blood+thrombin+CaCl2. "
10/01/1984 - "Localized coronary thrombosis was produced in the left anterior descending artery by endothelial injury and instillation of thrombin and fresh blood. "
03/01/1984 - "Most important in comparison to earlier European trials, streptokinase (STK) is administered now at the earliest time possible after acute coronary thrombosis. "
11/01/2015 - "The pathogenetic role of coronary thrombosis was definitively established in 1979 by demonstrating that intracoronary streptokinase rapidly restored flow in occluded infarct-related arteries, in contrast to intracoronary nitroglycerine which rarely did. "
01/01/2012 - "Diastolic timed Vibro-Percussion at 50 Hz delivered across a chest wall sized meat barrier enhances clot dissolution and remotely administered Streptokinase effectiveness in an in-vitro model of acute coronary thrombosis."
06/01/1989 - "All patients showed objective evidence of coronary thrombosis (contrast angiography) followed by later evidence of streptokinase (SK)-induced restoration of antegrade blood flow in the infarct-related coronary artery (as determined by repeat angiography). "
09/01/1987 - "Multiple coronary thromboses in previously normal coronary arteries treated with streptokinase."
|9.||Fibrinolytic Agents (Antithrombotic Agents)IBA
10/01/1984 - "In view of current interest in the possibility of rapid, high-dose administration of thrombolytic agents by the intravenous route in patients with coronary thrombosis (AMI), a study of this technique was carried out in the dog. "
01/01/2011 - "Coronary thrombosis was caused by a hypercoagulable state related to a haemolytic crisis of paroxysmal nocturnal haemoglobinuria and the patient was treated conservatively with antithrombotic agents. "
11/01/2001 - "[Primary prevention of coronary thrombosis by antithrombotic agents]."
05/01/1995 - "A new animal model of coronary thrombosis and effects of antithrombotic agents."
07/01/1994 - "Herrick's hypothesis, plus documentation that coronary thrombosis resulted in an acute MI presented investigators with the theory that thrombolytic agents could potentially prevent or limit the extent of myocardial damage. "
|10.||Serotonin (5 Hydroxytryptamine)IBA
11/01/1993 - "(2) This could explain the efficacy of 5-HT2 antagonists in limiting coronary thrombosis despite the limited role of 5-HT in primary aggregation."
01/01/1990 - "It is concluded that serotonin may be as important in mediating coronary thrombosis in man as it is in animals."
03/01/1979 - "Serotonin blockade during experimental coronary thrombosis."
08/01/2001 - "In view of the importance of serotonin in coronary thrombosis, and decreased platelet serotonin concentrations associated with SSRIs, the present study was performed to test the hypothesis of a decreased risk of acute myocardial infarction (AMI) associated with SSRIs. "
06/01/1953 - "Reflex and direct cardiopulmonary effects of 5-OH-tryptamine (serotonin); their possible role in pulmonary embolism and coronary thrombosis."
02/01/2007 - "Our study demonstrates that routine use of EXPORT catheter in patients with STEMI and coronary thrombosis is feasible, safe, and associated with significant improvements in flow-related angiographic parameters. "
06/15/2001 - "An acute coronary thrombosis was ruled out by left heart catheter-angio. "
02/01/1996 - "Coronary thrombosis was induced by injection of radioactive, autologous blood clots through a catheter placed in the left anterior descending coronary artery. "
04/01/1995 - "Coronary thrombosis was induced by injection of radioactive blood clot through a catheter placed in the left anterior descending coronary artery. "
03/01/1994 - "Coronary thrombosis was induced in eight dogs by injection of radioactive blood clot through a catheter placed in the left anterior descending coronary artery. "
|2.||Drug Therapy (Chemotherapy)
07/01/2011 - "Data shows that the risk of coronary thrombosis after antiplatelet drug withdrawal is much higher than that of surgical bleeding if the antiplatelet drug therapy were continued. "
03/01/2009 - "Three patients died, one from septic shock during chemotherapy (IVEA stage), another from mesenteric infarction (IAE stage) and the third from acute coronary thrombosis while in complete remission. "
06/01/1990 - "[Acute coronary thrombosis and myocardial ischemia following chemotherapy of Hodgkin's disease]."
11/01/2012 - "However, experience of primary percutaneous coronary intervention (PCI) and intravascular ultrasound imaging (IVUS) for coronary thrombosis, possibly due to cisplatin-based chemotherapy, has been limited. "
11/01/2012 - "Primary percutaneous coronary intervention and intravascular ultrasound imaging for coronary thrombosis after cisplatin-based chemotherapy."
|3.||Angioplasty (Angioplasty, Transluminal)
05/01/2012 - "We present a case of remnant guidewire into the left anterior descending artery (LAD) and aorta that led to acute coronary thrombosis following primary angioplasty. "
07/01/2004 - "Molecular imaging identifies regions with microthromboemboli during primary angioplasty in acute coronary thrombosis."
06/01/1995 - "Left main coronary thrombosis after radiofrequency ablation: successful treatment with percutaneous transluminal angioplasty."
09/01/1989 - "Facilitating factors are analysed, and the management of this complication is discussed: repeat angioplasty and/or emergency or elective coronary bypass, depending on the presence or absence of coronary thrombosis and symptoms, on the importance of the territory threatened and on the quality of collateral circulation."
03/01/1988 - "Apropos of a case of recurrent coronary thrombosis after angioplasty]."
03/08/2005 - "Plaque instability frequently occurs days or weeks before occlusive coronary thrombosis: a pathological thrombectomy study in primary percutaneous coronary intervention."
10/01/2013 - "This case shows that manual thrombectomy does not always allow for complete and safe removal of thrombotic material, especially when high-burden coronary thrombosis occurs in large, proximal vessels. "
05/01/2002 - "Early experience with a helical coronary thrombectomy device in patients with acute coronary thrombosis."
10/01/1993 - "Percutaneous rotational thrombectomy reduces acute reocclusion in an animal model of acute coronary thrombosis."
01/01/1989 - "Rotational thrombectomy in acute canine coronary thrombosis."