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Coproporphyrinogen Oxidase (Coproporphyrinogen III Oxidases)

An enzyme that catalyzes the oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX by the conversion of two propionate groups to two vinyl groups. It is the sixth enzyme in the 8-enzyme biosynthetic pathway of HEME, and is encoded by CPO gene. Mutations of CPO gene result in HEREDITARY COPROPORPHYRIA.
Also Known As:
Coproporphyrinogen III Oxidases; III Oxidases, Coproporphyrinogen; Oxidase, Coproporphyrinogen; Oxidases, Coproporphyrinogen III; Coproporphyrinogenase; Coproporphyrinogen:oxygen oxidoreductase (decarboxylating)
Networked: 52 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Taketani, Shigeru: 3 articles (12/2013 - 01/2006)
2. Hasan, Tayyaba: 2 articles (08/2013 - 09/2011)
3. Maytin, Edward V: 2 articles (08/2013 - 09/2011)
4. Anand, Sanjay: 2 articles (08/2013 - 09/2011)
5. Jones, Marjorie A: 2 articles (01/2008 - 01/2007)
6. Puy, Hervé: 2 articles (02/2004 - 01/2002)
7. Deybach, Jean-Charles: 2 articles (02/2004 - 01/2002)
8. Mazzetti, M B: 2 articles (10/2000 - 08/2000)
9. Sorianello, E M: 2 articles (10/2000 - 08/2000)
10. Mateva, Lyudmila: 1 article (01/2014)

Related Diseases

1. Hereditary Coproporphyria (Coproporphyrinogen Oxidase Deficiency)
2. Poisoning
3. Porphyrias
4. Hepatic Porphyrias (Hepatic Porphyria)
5. Acute Intermittent Porphyria (Porphyria, Acute)

Related Drugs and Biologics

1. Coproporphyria
2. Heme (Haem)
3. Protoporphyrinogen Oxidase (Protox)
4. Ferrochelatase (Heme Synthetase)
5. Uroporphyrinogen Decarboxylase (Uroporphyrinogen III Decarboxylase)
6. Porphyrins
7. Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)
8. Enzymes
9. Carbon Monoxide
10. protoporphyrin IX

Related Therapies and Procedures

1. Photochemotherapy (Photodynamic Therapy)