|5.||Wounds and Injuries (Trauma)
|1.||Rodrigues-Simioni, Léa: 15 articles (03/2015 - 04/2003)|
|2.||Hyslop, Stephen: 13 articles (03/2015 - 04/2003)|
|3.||Janssen, Paul M L: 12 articles (08/2014 - 01/2002)|
|4.||Shumaker, Peter R: 10 articles (04/2015 - 10/2011)|
|5.||Hildebrand, Kevin A: 10 articles (10/2014 - 10/2005)|
|6.||Léoty, C: 10 articles (12/2002 - 05/2000)|
|7.||da Cruz-Höfling, Maria Alice: 9 articles (03/2015 - 04/2003)|
|8.||Hart, David A: 9 articles (10/2014 - 10/2005)|
|9.||Schuster, Frank: 9 articles (01/2014 - 06/2005)|
|10.||Grishkevich, Viktor M: 8 articles (11/2015 - 07/2009)|
|1.||Caffeine (No Doz)FDA LinkGeneric
08/01/1993 - "After Ca2+ loading (120 s), the minimal caffeine concentration required to evoke a contracture in fatigued fibers (5.7 +/- 0.3 mM) was significantly greater than that of control fibers (3.1 +/- 0.4 mM), an effect that persisted with prolonged incubation of the skinned fibers. "
06/01/1992 - "In all cases, CICR evoked at pH 6.5 resulted in larger caffeine contractures than that evoked at 7.0, suggesting that more Ca2+ was released during CICR at the higher pH. Accordingly, rate constants for CICR were significantly greater at pH 7.0 than at pH 6.5. "
10/01/1989 - "The concentration of caffeine alone that increased the contracture tension by 7% averaged 6.7 +/- 0.3 mM for vastus, significantly greater than 4.1 +/- 0.2 mM for the rectus muscle biopsies. "
01/01/1990 - "The findings that human type I muscle fibers have higher caffeine sensitivity than type II muscle fibers should be helpful for the interpretation of the in vitro contracture test done in muscle strips containing type I and type II fibers in varying proportions."
04/01/1987 - "In early studies, caffeine was used as a tool to test the function of the intracellular contraction apparatus when the twitch or depolarization contracture was eliminated by a procedure that was thought to block the coupling part of the E-C coupling process. "
05/01/1989 - "1. The protective effects of some calcium antagonists against different forms of calcium overload contracture were investigated in embryonic chick cardiac myocytes. "
09/01/1983 - "Our results suggest that contracture can be reversed and that functional recovery can be improved in spite of increased tissue calcium."
12/01/1991 - "The results reported in the present study may be related to the impaired relaxation and contracture described in vivo within the first minutes of a postischemic reperfusion and before any change in calcium homeostasis."
06/01/1972 - "However, the fact that contractures are prolonged in the cold, and the finding that repriming is delayed, can be utilized in further studies to clarify the mechanism that controls the release of calcium."
01/01/2015 - "The calcium (Ca(2+))-paradox injury of the heart, induced by restoration of extracellular Ca(2+) after its short-term depletion, is known to provoke cardiomyocyte contracture. "
|3.||Halothane (Fluothane)FDA Link
09/01/1990 - "The effect of varying temperatures on biopsies of skeletal muscle from these animals showed a marked decrease in contracture response to halothane when the muscle was cooled to 25 degrees C. "
09/01/1990 - "The rate of tension development of cooling-induced contractures in the absence or presence of halothane was significantly greater in denervated (2-90 days) than in innervated muscles. "
07/01/1987 - "The magnitude of contractures was, however, significantly greater in the dynamic than in the static halothane test for halothane concentrations less than 3%, but this did not influence diagnosis. "
04/01/2011 - "The aim of this study was to investigate whether these agents can be considered possible substitutes for halothane in a modified in-vitro contracture test. "
09/01/1989 - "The present study examines lipid profiles of human muscle (vastus lateralis) prior to halothane challenge, relating the lipid profiles to the magnitude of halothane contracture response in muscle from the same biopsy. "
|4.||Adenosine Triphosphate (ATP)IBA
05/10/1988 - "All three compounds exerted a significant anti-ischaemic effect, as indicated by an improved recovery of functional parameters (left ventricular pressure and coronary perfusion), a delayed onset of the ischaemic contracture, and an enhanced recovery of biochemical (CrP, ATP and adenylate energy charge) parameters. "
01/01/2007 - "Adenosinergic contracture inhibition was eliminated by A(1)AR gene knockout (KO), mimicked by A(1)AR overexpression, and was associated with preservation of myocardial [ATP]. "
05/01/2015 - "In the present study, we have investigated the involvement of the Ca(2+)/ATP-activated K(+) channels in the regulation of both acute A1-withdrawal and CCk-8-induced contractures in the GPI preparation. "
09/01/1989 - "These studies lead us to conclude that the relatively poor recovery of contractile response of human atrial trabeculae, together with contracture reported previously at lower temperatures (1 degree and 4 degrees C), is not due to a failure to maintain adenosine triphosphate levels."
05/01/2015 - "A1-adenosine acute withdrawal response and cholecystokinin-8 induced contractures are regulated by Ca(2+)- and ATP-activated K(+) channels."
05/01/1993 - "The purpose of this study was to assess the efficacy of textured silicone implants in reducing the incidence of capsular contracture. "
02/01/2014 - "The study identifies PACE technology as a potential low-cost technique that is easy to use for reduction of capsular contracture after augmentation using silicone implants. "
02/01/2014 - "This study showed that the PACE application significantly reduces capsular contracture around silicone implants. "
02/01/2014 - "Thus, this study aimed to determine the potential of PACE to prevent or attenuate capsular contracture around silicone implants in a rodent model. "
05/01/2013 - "Relative risks (RR) of capsular contracture (CC), moderate to severe malposition, and secondary procedure were calculated using Cox proportional hazards regression, adjusting for patient, procedure, and device characteristics among patients enrolled in the primary augmentation cohorts of the Core (NCT00689871; round, silicone-filled implants) and 410 (NCT00690339; shaped, highly cohesive silicone-filled implants) clinical studies. "
|6.||Botulinum Toxins (Botulinum Toxin)IBA
09/01/2014 - "Type A botulinum toxin was applied to 12 patients in the subacromial space around the rotator cuff conjoint tendon, as well as in the painful spots and in the muscle contracture in the shoulder. "
02/01/2012 - "We here report our experience with botulinum toxin in post-radiosurgical neck contracture. "
12/16/2011 - "To evaluate the effectiveness and safety of infiltrating the psoas muscle with botulinum toxin guided by computerised tomography (CT) in order to reduce dynamic contracture in bending the hip. "
09/15/2010 - "Botulinum toxin A is used to treat contractures in children with spasticity by temporarily interfering with neural transmission at the motor end plate. "
01/01/2009 - "EMMA 1) age 2-4 years, RI 20%: multilevel injection of botulinum toxin in case of muscular hyperactivity without morphological alterations of the couple muscle-tendon (contractures). "
|7.||zafirlukast (Accolate)FDA LinkGeneric
10/01/2012 - "The present study suggests that zafirlukast may be effective in reducing breast capsule distortion in patients with long-standing contracture, though reduced capsular contracture values are strictly related to the duration of drug intake."
01/01/2005 - "Zafirlukast appears effective in treating early capsular contracture after primary submuscular breast augmentation using saline-filled, smooth-walled implants. "
07/01/2002 - "Zafirlukast (Accolate): A new treatment for capsular contracture."
07/01/2007 - "Effects of zafirlukast on capsular contracture: controlled study measuring the mammary compliance."
01/01/2005 - "The purpose of this study was to prospectively examine a single surgeon's experience using zafirlukast in the treatment of capsular contracture in primary, submuscular breast augmentation with saline-filled, smooth-walled implants. "
|8.||Collagenases (Collagenase)FDA Link
07/01/2014 - "Although further studies are needed, repeated administration of collagenase appears to be safe and modestly effective for severe Dupuytren's contractures, although a fasciectomy may ultimately be required in the most severe cases. "
10/01/2015 - "Collagenase-treated participants experienced significant reduction in contracture and an increased range of motion compared with placebo-treated participants. "
10/01/2012 - "This prospective study reports on the short-term safety and efficacy of collagenase treatment in five thumb and first web space Dupuytren's contractures. "
02/01/2015 - "Correction at metacarpophalangeal and proximal interphalangeal joints, taken individually, are comparable with the Collagenase Option for the Reduction of Dupuytren's studies at 43° and 33°, respectively, however due to the multi-cord injection, we achieved 94° average immediate and 76° average final combined metacarpophalangeal and proximal interphalangeal contracture releases per bottle of enzyme. "
10/01/2012 - "Previous studies have reported on the effectiveness of collagenase in finger contractures. "
01/01/1989 - "Analysis of the late results has shown that contractures have been eliminated or reduced in 70% of the patients, but a good cosmetic effect has been achieved in only 30%. "
05/01/2013 - "The use of Strattice is safe and may be helpful in the management of certain situations in cosmetic breast surgery, including needed lower pole support, capsular contracture, rippling, and implant malposition. "
02/01/2015 - "This tissue-sparing technique results in low recurrence rates, high patient satisfaction with relatively short healing times and favourable cosmetic outcomes without contractures."
01/01/2014 - "Such postburn contractures causes distressing symptoms to the patients and in the management of these contractures, both functional and cosmetic appearance should be the primary concern. "
09/01/2013 - "There was also an increase in severe capsular contractures and an inferior cosmetic result in the irradiated patients. "
12/01/1995 - "Polyurethane-covered implants were associated with a significant reduction in the risk of contracture for at least 7 years following implantation. "
01/01/1989 - "Twelve patients with severe and recurrent capsular contractures following breast augmentation and reconstruction were improved with polyurethane-covered implants. "
03/01/2015 - "This 30-year study is the longest examination of the use of polyurethane-coated implants and their correlation with capsular contracture. "
10/01/2015 - "A more permanent matrix equivalent to polyurethane may be the solution for reducing long-term capsular contracture. "
10/01/2015 - "After 20 years, the polyurethane is almost undetectable and capsular contracture may appear. "
03/01/2008 - "A short period of splinting of meshed skin grafts during the initial phase of epithelialization and keratinocyte differentiation may be most effective in the prevention of subsequent contractures in vivo but additional studies are needed to establish this."
01/01/1999 - "Among the methods of treatment, excision with graft gives the best results in short flexion contractures. "
07/01/1984 - "Best results were obtained by release of contracture, application of split-thickness skin grafts, and splinting for up to six months."
12/01/1982 - "Best results are obtained if contracture release is complete, if defects are covered by thick split-thickness skin grafts, and if nipple-areola reconstruction is obtained from a normal opposite breast if present. "
01/01/2006 - "Very good results and complete resolution of contractures were obtained in 15 cases, while 2 patients underwent a repeated surgery in which compound grafts were used again. "
|2.||Prostheses and Implants (Prosthesis)
10/01/1988 - "Although the weight of evidence generally indicates that improved contracture rates with retropectoral placement of the prosthesis and excellent aesthetic results can be obtained with this approach, there remains a significant cadre of surgeons who believe their own retromammary results are equal to or better than the alternative. "
05/01/2012 - "All 3 patients who had surgery experienced significant improvement of socket contracture that enabled patients to wear a prosthesis again. "
01/01/2005 - "Although surgical techniques and the quality of mammary prostheses have been improved significantly in recent years, capsular contracture attendant on prosthetic mammary reconstruction remains a major flaw. "
01/01/1987 - "We conclude that in this personal series of patients, subpectoral placement of the prosthesis has significantly reduced but not eliminated the occurrence of capsule contracture without sacrificing a normal breast appearance."
11/01/2012 - "Its putative advantages include improved positioning of the prosthesis, better definition of the inframammary fold, amelioration of potential contracture, and overall enhancement of cosmesis. "
|3.||Skin Transplantation (Skin Grafting)
11/01/2009 - "This type of breast contracture can be successfully eliminated with the author-suggested, improved free-skin grafting technique. "
01/01/2007 - "Skin grafting is widely used for the treatment of postburn contractures. "
03/01/2011 - "As a result of the counter flaps transposition, the contracture is eliminated; the web space's shape and depth are restored by the use of flaps alone or in combination with skin grafting. "
08/01/2015 - "Six patients who had undergone skin grafting were found to have some degrees of skin contracture, while none of the patients who had undergone flap coverage showed any signs of contracture recurrence. "
10/01/2014 - "Flexion contractures and pseudosyndactyly can be treated with surgery but usually require skin grafting. "
|4.||Breast Implants (Breast Implant)
06/01/2006 - "Numerous randomized controlled trials addressing the efficacy of textured surface breast implants in reducing capsular contracture have yielded nonuniform results. "
01/01/2015 - "A large number of clinical studies have reported that the different materials used in breast implants were a possible cause of the different incidence rates of capsular contracture observed in patients after implantation. "
12/01/2010 - "This study aimed to observe the relationship between the number of myofibroblasts, the tensile strength of the breast implant capsule, and the degree of breast capsular contracture. "
02/01/2010 - "Results from this study highlight the importance of the wingless signaling pathway in the pathogenesis of radiation-induced fibroproliferation associated with capsular contracture in expander/implant breast reconstruction."
06/01/2006 - "Textured surface breast implants in the prevention of capsular contracture among breast augmentation patients: a meta-analysis of randomized controlled trials."
06/01/2014 - "The proximal interphalangeal joints that improved spontaneously after metacarpophalangeal injection or received direct injections showed 51-55% reduction in contracture. "
12/01/2013 - "Clinical use, including number of injections per cord and effectiveness outcomes (joint contracture and range of motion) were compared with results from 2 registration trials. "
07/01/2013 - "Between January 2010 and January 2012 all patients who had failed non-operative treatment including anti-inflammatory medication, physiotherapy and glenohumeral joint injections for contracture of the shoulder and who subsequently underwent an ACR were enrolled in the study. "
01/01/2009 - "This study quantified with Gait Analysis (GA) the gait pattern of a 4-year-old diplegic child with calf contracture before, 5 days, and 3 months after BTA injections into gastrocnemius. "
05/01/2015 - "The percentage of PIP joints achieving clinical success (0° to 5° of full extension), clinical improvement (50% or more reduction in baseline contracture), and range of motion improvement at 30 days after the first and last CCH injections was assessed. "