Condylomata Acuminata (Genital Wart)

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742 relevant articles (104 outcomes, 105 trials/studies) found for this Disease

Description: Sexually transmitted form of anogenital warty growth caused by the human papillomaviruses.

Also Known As:

Genital Wart; Genital Warts; Venereal Wart; Wart, Genital; Wart, Venereal; Venereal Warts; Warts, Genital; Warts, Venereal

Relationship Network

Disease Context: Research Results

Related Diseases

1.	Neoplasms (Cancer)
2.	Infection
3.	Condylomata Acuminata (Genital Wart)
4.	Warts (Wart)
5.	Actinic Keratosis

Experts

1.	Koutsky, Laura A: 2 articles (04/2008 - 11/2002)
2.	Hicks, D: 2 articles (04/2007 - 01/2001)
3.	Georgala, S: 2 articles (09/2006 - 06/2004)
4.	Katoulis, A C: 2 articles (09/2006 - 06/2004)
5.	Georgala, C: 2 articles (09/2006 - 06/2004)
6.	Park, S K: 2 articles (09/2003 - 03/2003)
7.	Kim, W: 2 articles (09/2003 - 03/2003)
8.	Ferenczy, A: 2 articles (02/2002 - 04/2001)
9.	Fife, K H: 2 articles (02/2002 - 04/2001)
10.	Smolensky, Michael H: 1 article (04/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Condylomata Acuminata:

1.	imiquimod (Aldara)FDA Link 04/01/2001 - "When 5% imiquimod cream is applied three times a week up to 16 weeks, approximately two thirds of women treated with imiquimod achieve complete clearance of genital warts, whereas only about one third of men clear completely. " 09/01/2000 - "CONCLUSION: The study demonstrated that 2% imiquimod in cream with mild non-objective side effects is safe, tolerable and significantly more effective than placebo in curing external genital warts in males." 07/01/1998 - "In conclusion, the data presented demonstrate that 2% imiquimod in cream with mild to moderate subjective side effects is significantly more effective than placebo in eliminating genital warts in women." 04/01/1998 - "Patient-applied 5% imiquimod cream is effective for the treatment of external genital warts and has a favorable safety profile." 04/01/2009 - "Imiquimod is a topically used immune response modifier effective in the treatment of genital warts caused by HPV. " Order ALL the reference details at left...
2.	InterferonsIBA 11/01/1989 - "We consider the systemic treatment with interferon for condylomata acuminata to be highly effective and well tolerated. " 03/01/1994 - "Recently, studies have suggested that interferons would be effective in the treatment of some genital warts. " 10/23/1986 - "We conclude that injection of interferon alpha-2b directly into genital warts appears to be an effective and fairly well-tolerated form of therapy." 01/01/1998 - "BACKGROUND: Pilot studies of adjuvant therapy with topically applied interferons (IFN) have shown promising results in reducing the recurrence of condylomata acuminata (CA). " 06/01/1987 - "Interferons are proving useful in the management of recalcitrant condylomata acuminata. " Order ALL the reference details at left...
3.	Podophyllotoxin (Condylox)FDA LinkGeneric 02/01/1995 - "In the therapeutic arsenal for the treatment of condylomata, podophyllotoxin 0.5% is a first line treatment for condylomata acuminata of the genital mucous membranes." 10/01/1990 - "Thus, 0.5% podofilox solution appears to be an effective treatment for condylomata acuminata, with acceptable side effects that are local and temporary." 12/01/1990 - "In conclusion podophyllotoxin 0.5% appeared to be safe and effective for the self treatment of genital warts." 01/01/1993 - "The purpose of this comparative open study was to determine the clinical efficacy of 0.3% podophyllotoxin both in 70% ethanolic solution and cream preparations on genital warts. " 12/01/1995 - "OBJECTIVE--To evaluate the clinical efficacy of a 0.15% and a 0.3% cream formulation of podophyllotoxin in comparison with the 0.5% solution in the treatment of condylomata acuminata and to compare the treatment modalities regarding side effects. " Order ALL the reference details at left...
4.	Fluorouracil (Carac)FDA LinkGeneric 07/01/1987 - "It is concluded that weekly topical application of 5% 5-fluorouracil is well tolerated and highly effective in treating vaginal condylomata acuminata." 07/01/1990 - "I conclude that topical 5-FU is effective for treatment of vulvar condylomata acuminata and that periodic applications are preferable to continuous applications." 07/01/1982 - "Topical 5-FU helpful in reducing the rate of recurrence of condylomata acuminata." 12/01/1975 - "Observations on a clinico-therapeutic trial with topical 5-fluor-uracil (EFUDIX) in condylomata acuminata." 10/01/1991 - "Biopsy-proven vaginal adenosis appeared 8 months after intravaginal 5-fluorouracil application for recurrent urogenital condylomata acuminata. " Order ALL the reference details at left...
5.	VaccinesIBA 07/23/2009 - "The following paper represents a summary of the full-text version of the German evidence-based Guidelines, including all evidence-based recommendations regarding the safety as well as the efficacy of the vaccines in preventing CIN, VIN/VaIN, genital warts and other HPV-associated lesions." 10/01/2008 - "The aim of this work was to study the human papillomavirus (HPV) type-distribution in condylomata acuminata (CA) of mainland China and to estimate the potential role of HPV prophylactic vaccines for CA in mainland China. " 03/30/2006 - "Furthermore, phase 2 trials of a bivalent vaccine designed to protect against high-risk HPV types 16 and 18 and a quadrivalent vaccine designed to protect against HPV 16 and 18, and low-risk, genital wart-causing HPV 6 and 11 have demonstrated that VLP vaccines reduce the incidence of HPV-associated disease in vaccinated individuals. " 04/01/2009 - "Human papillomavirus, genital warts, and vaccines." 01/01/2008 - "One of the vaccines (a quadrivalent vaccine) also prevents two HPV types associated with 90% of genital warts. " Order ALL the reference details at left...
6.	type 6,11,16,18 human papillomavirus vaccine L1 (Gardasil)IBA 08/19/2008 - "Gardasil was also highly efficacious at preventing vaginal/vulvar lesions and genital warts. " 02/01/2008 - "Data from the Phase III trial demonstrated that Gardasil was 100% effi cacious in preventing precancerous lesions of the cervix, vulva, and vagina and effective against genital warts. " 07/01/2006 - "Gardasil also targets HPV-16 and -18, plus the HPV-6 and -11 types responsible for more than 80% of genital warts. " 01/01/2007 - "One of these (Gardasil, recently licensed) contains all four HPV types, offering protection against genital warts (types 6 and 11) as well as cervical cancer. " 02/01/2007 - "GARDASIL is the first vaccine approved for use in women aged 9-26 years for the prevention of cervical cancer and genital warts, as well as vulvar and vaginal precancerous lesions. " Order ALL the reference details at left...
7.	Interferon-alpha (Interferon Alfa)FDA Link 01/22/1988 - "Natural interferon alfa given intralesionally is an effective and safe treatment even in patients with recurrent or recalcitrant genital warts." 11/01/1988 - "This study demonstrates that parenterally administered Wellferon produces clearance of resistant genital warts in many patients, and that rates of clearance do not appear to vary between groups receiving moderate or low dose therapy." 11/01/1994 - "The purpose of this double-blind, placebo-controlled study was to determine and compare the clinical efficacy and tolerance of human leukocyte alpha-interferon (incorporated 2 x 10(6) IU/g) in hydrophilic cream to cure genital warts. " 11/01/1989 - "In the present study we used the well known antiviral properties of interferon alpha 2b in condylomata acuminata. " 05/01/1986 - "This study shows that systemic human lymphoblastoid interferon is active in treating severe recurrent genital warts in women with a history of recalcitrant disease." Order ALL the reference details at left...
8.	PodophyllinIBA 04/01/2001 - "Topical application of podophyllin solution, long considered the therapy of first choice against condylomata acuminata, can no longer be recommended due to its low efficacy and gross toxicity. " 04/01/1995 - "INTRODUCTION--Topical application of podophyllin is a routine procedure in patients with ano-genital warts. " 04/01/1992 - "Podophyllin, a plant derivative of variable composition, is used widely within New Zealand as a treatment for genital warts. " 04/01/1992 - "Chromosomal changes in Chinese hamster AA8 cells caused by podophyllin, a common treatment for genital warts." 10/01/1989 - "Scissor excision is therefore preferable to podophyllin application in the treatment of perianal condylomata acuminata." Order ALL the reference details at left...
9.	DNA (Deoxyribonucleic Acid)IBA 03/01/1992 - "The method yielded positive results for HPV DNA 6/11 in 5 cases with condylomata acuminata (100%) and in 2 of 47 with flat warty lesions (4.2%), whereas HPV DNA 16/18 was detected in 29/47 of the latter group (61.7%). " 08/01/2003 - "BACKGROUND: Only a few studies have been done involving detection of human papillomavirus (HPV) DNA on the external genitalia of men without genital warts, although many have been done for women. " 06/01/2006 - "In patients with genital warts, however, HPV DNA was found in 6/10 (60%) of cases. " 09/01/2005 - "To determine the correlation between deoxyribonucleic acid (DNA) loads of human papillomavirus (HPV) and recurrence of condylomata acuminata (CA), 31 cases of primary CA and 32 cases of recurrent CA were assayed for the HPV6/11 and HPV16/18 DNA loads by real-time fluorogenic quantitative PCR. " 09/01/2005 - "Correlation between deoxyribonucleic acid loads of human papillomavirus and recurrence of condylomata acuminata." Order ALL the reference details at left...
10.	Lidocaine (Xylocaine)FDA LinkGeneric 06/14/1993 - "In an open prospective study 67 patients with refractory genital warts, irrespective of anatomic localization, received CO2-laser vaporization in local anaesthesia, using lidocaine 2% as the local anaesthetic. " 07/01/1993 - "Particular benefit has also been shown with use of eutectic lidocaine/prilocaine cream in association with treatment of condylomata acuminata in both men and women, and it appears to provide a useful alternative to lidocaine infiltration in this context. " 07/01/1997 - "METHODS: Men, scheduled for removal of genital warts by cryotherapy, were randomly selected to receive one of three treatments: (1) lidocaine/prilocaine cream application, (2) 1% lidocaine infiltration, and (3) lidocaine/prilocaine cream application followed by infiltration of 1% lidocaine. " 08/15/1989 - "Using an percutaneous anesthetic Lidocaine ointment (EMLA cream 5%), we treated patients with mollusca contagiosa, condylomata acuminata, and verrucae plantaris by superficial curettage or electrocaustic surgery. " 07/01/1990 - "Treatment of genital warts by laser surgery was performed in 100 male patients under local infiltration (2-6 ml 1% Xylocaine) or topical anesthesia with 2.5-7.5 ml EMLA cream. " Order ALL the reference details at left...

Therapies and Procedures

1.	Cryotherapy (Therapy, Cold) 01/01/1987 - "We conclude that cryotherapy for cervical condylomata acuminata is an effective and safe procedure during the last two-thirds of pregnancy." 03/01/1991 - "A clinical controlled study is presented for the treatment of condylomata acuminata with cryotherapy in 64 patients. " 03/01/1991 - "Cryotherapy in the treatment of condylomata acuminata: a controlled study of 64 patients." 08/26/2000 - "This condition was previously diagnosed as 'genital warts', for which she received extensive cryotherapy at another clinic. " 02/01/1999 - "Cryotherapy is regularly used in our clinic for treating genital warts. " Order ALL the reference details at left...
2.	Laser Therapy (Surgery, Laser) 07/01/1996 - "Laser therapy is widely accepted as a safe and effective means of treating genital condylomata acuminata. " 02/01/1998 - "Two patients developed genital warts and were treated with laser vaporization. " 03/01/1995 - "The first results of laser therapy in treatment of condylomata acuminata of male reproductive organs are reported. " 01/01/1990 - "Sixteen pregnant women with genital condylomata acuminata were treated with laser vaporization to assess effectiveness, complication rate, and impact on recurrence. " 04/01/1988 - "Some concerns about current laser surgery of condylomata acuminata." Order ALL the reference details at left...
3.	Injections 10/01/2004 - "In the univariate analysis, history of genital warts (P = 0.01), sexually transmitted disease (P = 0.001), premarital sexual intercourse (P = 0.002), sexual contact with a commercial sex worker (P = 0.003), being employed (P = 0.011) and having more than 10 injections for medical purposes (P = 0.006) all correlated with being HIV-infected. " 02/01/1990 - "This study design was to give 1 million units interferon alfa-2b intralesionally into the base of each of five external genital warts per patient, on a Monday-Wednesday-Friday treatment schedule for 3 weeks (total of nine injections). " 12/01/1990 - "These results suggest that in contrast to condylomata acuminata bowenoid papulosis lesions respond better to continuous than to intermittent interferon gamma injections." 05/12/1984 - "Intramuscular human interferon-beta injections in treatment of condylomata acuminata." 12/01/1979 - "Effect of injections of small doses of human fibroblast interferon into genital warts. " Order ALL the reference details at left...
4.	Gas Lasers 01/01/1990 - "[Treatment of condylomata acuminata: efficacy of the carbon dioxide laser]" 02/01/1985 - "Uncontrolled trials indicate that treatment of condylomata acuminata with the carbon dioxide laser is effective and probably superior to conventional surgical treatment. " 01/01/2001 - "We have observed 3 cases of vulvodynia after CO2 laser (pulse or scan) treatment of condylomata acuminata (n = 1) or bowenoid papulosis (n = 2) of the female genital mucosa. " 12/01/1996 - "Carbon dioxide laser vaporization for genital wart." 03/01/1995 - "[Treatment of condylomata acuminata of the male reproductive organs with CO2 laser under colposcopic control]" Order ALL the reference details at left...
5.	Lasers (Laser) 06/01/1985 - "The laser appears to be an effective method of treatment for recurrent or persistent condylomata acuminata provided that (1) the patient is not immunosuppressed, (2) the potentially infected sexual partner is examined and treated, if necessary, and (3) the external genitalia, including the anus, vagina and cervix, are carefully examined colposcopically to rule out the persistence of small lesions." 08/01/1998 - "MATERIALS AND METHODS: Between October 1994 and March 1997, 6 men with rapidly recurrent external and intraurethral condylomata acuminata underwent BCG therapy after initial laser treatment. " 04/01/1996 - "Laser treatment of genital condylomata acuminata." 03/01/1995 - "However, human papillomavirus types that cause genital warts seem to have a predilection for infecting the upper airway mucosa, and laser plume containing these viruses may represent more of a hazard to the surgeon." 07/01/1994 - "[Laser applications in condylomata acuminata]" Order ALL the reference details at left...

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