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Complement C9 (Complement Component 9)

A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
Also Known As:
Complement Component 9; C9 Complement; Complement 9; C9, Complement; Complement, C9; Component 9, Complement
Networked: 27 relevant articles (1 outcomes, 0 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Wang, X: 1 article (11/2014)
2. Gao, X: 1 article (11/2014)
3. Zhou, J: 1 article (11/2014)
4. Su, Z: 1 article (11/2014)
5. Wüthrich, R P: 1 article (11/2014)
6. Beyer, R P: 1 article (11/2014)
7. Shi, M: 1 article (11/2014)
8. Liu, Y: 1 article (11/2014)
9. Zhang, J: 1 article (11/2014)
10. Hu, H: 1 article (11/2014)

Related Diseases

1. Infection
2. Chronic Hepatitis B
3. Hepatocellular Carcinoma (Hepatoma)
4. Systemic Lupus Erythematosus (Libman-Sacks Disease)
5. Necrosis

Related Drugs and Biologics

1. Complement Factor B (Factor B)
2. Complement System Proteins (Complement)
3. Caspase 3 (Caspase-3)
4. Troponin I
5. P-Selectin
6. Apolipoprotein A-I (Apolipoprotein A1)
7. Zinc
8. Vitamin A (Retinol)
9. Proteins (Proteins, Gene)
10. Iron