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Complement C9 (Complement Component 9)

A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
Also Known As:
Complement Component 9; C9 Complement; Complement 9; C9, Complement; Complement, C9; Component 9, Complement
Networked: 49 relevant articles (1 outcomes, 2 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Heckmann, Veronika: 1 article (02/2022)
2. Kuzma, Mónika: 1 article (02/2022)
3. Mayer, Matyas: 1 article (02/2022)
4. Simon, Gábor: 1 article (02/2022)
5. Tóth, Dénes: 1 article (02/2022)
6. Arya, Rakesh: 1 article (01/2022)
7. Bishwal, Subasa Chandra: 1 article (01/2022)
8. Kaushik, Sandeep Rai: 1 article (01/2022)
9. Liu, Chuan-Ju: 1 article (01/2022)
10. Malik, Md Zubbair: 1 article (01/2022)

Related Diseases

1. Hepatitis B
2. Chronic Hepatitis B
3. Hepatocellular Carcinoma (Hepatoma)
4. Inflammation (Inflammations)
5. Peripheral Nerve Injuries

Related Drugs and Biologics

1. Proteins (Proteins, Gene)
2. Immunoglobulin G (IgG)
3. Proteome
4. Complement Membrane Attack Complex (Membrane Attack Complex)
5. Complement System Proteins (Complement)
6. Complement Factor B (Factor B)
7. Antibodies
8. Vitronectin
9. Complement C9 (Complement Component 9)
10. alpha-2-HS-Glycoprotein