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Complement C3 (C3 Complement)

A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase.
Also Known As:
C3 Complement; Complement 3; Complement Component 3; C3 Precursor; Complement C3 Precursor; Precursor-Complement 3; Pro-C3; Pro-Complement 3; C3 Precursor, Complement; C3, Complement; Complement, C3; Component 3, Complement; Precursor Complement 3; Precursor, C3; Precursor, Complement C3; Pro C3; Pro Complement 3
Networked: 1636 relevant articles (47 outcomes, 165 trials/studies)

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Bio-Agent Context: Research Results

Experts

1. Feng, Lin: 24 articles (03/2020 - 08/2015)
2. Liu, Yang: 24 articles (03/2020 - 05/2014)
3. Jiang, Wei-Dan: 23 articles (03/2020 - 08/2015)
4. Wu, Pei: 23 articles (03/2020 - 08/2015)
5. Zhou, Xiao-Qiu: 23 articles (03/2020 - 08/2015)
6. Kuang, Sheng-Yao: 21 articles (03/2020 - 08/2015)
7. Tang, Ling: 21 articles (03/2020 - 08/2015)
8. Karsdal, Morten A: 20 articles (02/2022 - 01/2013)
9. Jiang, Jun: 19 articles (02/2020 - 08/2015)
10. Leeming, Diana J: 17 articles (01/2022 - 01/2013)

Related Diseases

1. Fibrosis (Cirrhosis)
2. Infections
3. Proteinuria
4. Inflammation (Inflammations)
5. Nephritis

Related Drugs and Biologics

1. Immunoglobulin G (IgG)
2. Biomarkers (Surrogate Marker)
3. Proteins (Proteins, Gene)
4. Immunoglobulin M (IgM)
5. Muramidase (Lysozyme)
6. Acid Phosphatase
7. Interleukin-6 (Interleukin 6)
8. Messenger RNA (mRNA)
9. Complement System Proteins (Complement)
10. Immunoglobulins (Immunoglobulin)

Related Therapies and Procedures

1. Aftercare (After-Treatment)
2. Therapeutics
3. Ligation
4. Drug Therapy (Chemotherapy)
5. Carotid Endarterectomy