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Complement C2 (Complement Component 2)

A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
Also Known As:
Complement Component 2; C2 Complement; Complement 2; C2, Complement; Complement, C2; Component 2, Complement
Networked: 64 relevant articles (0 outcomes, 4 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Silvestri, Giuliana: 3 articles (09/2012 - 02/2009)
2. Chakravarthy, Usha: 3 articles (09/2012 - 02/2009)
3. McKay, Gareth J: 3 articles (09/2012 - 02/2009)
4. Allikmets, Rando: 3 articles (07/2011 - 04/2006)
5. Seddon, Johanna M: 2 articles (11/2015 - 09/2012)
6. Hughes, Anne E: 2 articles (05/2013 - 02/2009)
7. Ryu, Euijung: 2 articles (09/2012 - 01/2009)
8. Edwards, Albert O: 2 articles (09/2012 - 01/2009)
9. Hageman, Gregory S: 2 articles (07/2011 - 04/2006)
10. Guymer, Robyn H: 2 articles (07/2011 - 02/2009)

Related Diseases

1. Macular Degeneration (Age-Related Maculopathy)
2. Systemic Lupus Erythematosus (Libman-Sacks Disease)
3. Infection
4. Wounds and Injuries (Trauma)
5. Discoid Lupus Erythematosus

Related Drugs and Biologics

1. Complement Factor B (Factor B)
2. Complement C2 (Complement Component 2)
3. Complement Factor H (Factor H)
4. Complement C3 (C3 Complement)
5. Serine (L-Serine)
6. Complement System Proteins (Complement)
7. Proteins (Proteins, Gene)
8. Apolipoproteins E (ApoE)
9. Apolipoproteins
10. Perforin