Common Cold

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752 relevant articles (73 outcomes, 151 trials/studies) found for this Disease

Description: A catarrhal disorder of the upper respiratory tract, which may be viral or a mixed infection. It generally involves a runny nose, nasal congestion, and sneezing.

Also Known As:

Catarrh; Acute Coryza; Catarrhs; Colds, Common; Common Colds; Cold, Common; Coryza, Acute

Relationship Network

Disease Context: Research Results

Virus Diseases: 1376

RNA Virus Infections: 46

Picornaviridae Infections: 39

Common Cold: 752

Respiratory Tract Diseases: 377

Respiratory Tract Infections: 5595

Common Cold: 752

Related Diseases

1.	Infection
2.	Cough
3.	Rhinitis
4.	Sneezing
5.	Hypersensitivity (Allergy)

Experts

1.	Hemilä, Harri: 6 articles (10/2007 - 01/2002)
2.	Douglas, R M: 4 articles (01/2007 - 01/2000)
3.	Arroll, B: 4 articles (01/2005 - 01/2000)
4.	Kenealy, T: 4 articles (01/2005 - 01/2000)
5.	Taverner, D: 3 articles (01/2007 - 01/2000)
6.	Treacy, B: 3 articles (01/2007 - 01/2000)
7.	Albanes, Demetrius: 3 articles (08/2006 - 01/2002)
8.	Kaprio, Jaakko: 3 articles (08/2006 - 01/2002)
9.	Virtamo, Jarmo: 3 articles (08/2006 - 01/2002)
10.	Turner, Ronald B: 3 articles (10/2005 - 12/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Common Cold:

1.	ZincIBA 05/01/2003 - "Zinc nasal gel effective for the common cold." 10/01/2000 - "These results provide evidence that zinc nasal gel is effective in shortening the duration of common cold symptoms off when taken within 24 hours of their onset." 10/01/2006 - "AIM: To determine the efficacy of prophylactic administration of zinc sulphate in reducing the occurrence of the common cold in children, and to evaluate the efficacy of zinc sulphate in reducing the duration and severity of cold symptoms. " 08/01/2000 - "Zinc lozenges--a cure for common colds?" 11/01/1996 - "Zinc lozenges as cure for common colds." Order ALL the reference details at left...
2.	Ascorbic Acid (Vitamin C)FDA LinkGeneric 01/01/1997 - "However, in four studies with British male schoolchildren and students a statistically highly significant reduction in common cold incidence was found in groups supplemented with vitamin C (pooled RR 0.70; 95% CI 0.60, 0.81). " 04/01/1995 - "He found that episodes were 0.11 +/- 0.24 (SE) days shorter in the vitamin C groups and concluded that there was no valid evidence to indicate that vitamin C is beneficial in the treatment of the common cold. " 05/01/2009 - "CONCLUSIONS: Vitamin C is frequently used for the treatment and prophylaxis of the common cold; however, no published recommendations were found in a review of the nurse practitioner literature that specifically address the efficacy of vitamin C for the common cold. " 02/01/1979 - "Vitamin C: cure for the common cold?" 02/01/2009 - "With regard to the common cold different studies including meta-analyses underline that the prophylactic intake of vitamin C may slightly reduce the duration of the illness in healthy persons but does not affect its incidence and severity. " Order ALL the reference details at left...
3.	gluconic acid (gluconate)FDA LinkGeneric 03/01/1997 - "A randomized, double-blind, placebo-controlled clinical trial has shown that treatment of the common cold with zinc gluconate lozenges resulted in a significant reduction in duration of symptoms of the cold. " 02/01/2006 - "OBJECTIVE: Commercial preparations of intranasal zinc gluconate gel are marketed as a remedy for the common cold. " 07/15/1996 - "To test the efficacy of zinc gluconate lozenges in reducing the duration of symptoms caused by the common cold. " 01/01/1987 - "A recently published randomized, controlled, double-blind, study has reported efficacy of zinc gluconate lozenge treatment of the common cold. " 01/01/1999 - "Some studies support the use of zinc gluconate lozenges to treat the common cold, but there are insufficient data at this time to recommend the routine use of these lozenges. " Order ALL the reference details at left...
4.	Anti-Bacterial Agents (Antibiotics)IBA 01/01/2000 - "BACKGROUND: The common cold is caused by viruses which cannot be helped by antibiotics. " 05/01/2009 - "CONCLUSIONS: Antibiotics are often prescribed or dispensed to treat common colds. " 01/01/2006 - "Public views and use of antibiotics for the common cold before and after an education campaign in New Zealand." 03/01/2005 - "While none of the pediatricians reported prescribing antibiotics for the common cold, 17% of the family physicians did so (p = 0.006). " 03/01/2005 - "35 (2002) 113] There is good evidence and consensus that there is no indication for antibiotics for the common cold. " Order ALL the reference details at left...
5.	Nasal Decongestants (Decongestants)IBA 01/01/2009 - "OBJECTIVES: To assess the efficacy of nasal decongestants at reducing the symptom of nasal congestion in adults and children with the common cold and to identify possible adverse effects associated with their use. " 01/01/2007 - "OBJECTIVES: To assess the efficacy of nasal decongestants at reducing the symptom of nasal congestion in adults and children with the common cold and to identify possible adverse effects associated with their use. " 01/01/2004 - "OBJECTIVES: To assess the efficacy of nasal decongestants at reducing the symptom of nasal congestion in adults and children with the common cold and to identify possible adverse effects associated with their use. " 01/01/2000 - "OBJECTIVES: To assess the efficacy of nasal decongestants at reducing the symptom of nasal congestion in adults and children with the common cold and to identify possible adverse effects associated with their use. " 01/01/2009 - "SELECTION CRITERIA: Randomised, placebo controlled trials of single-active oral and topical nasal decongestants in adults and children suffering from common cold. " Order ALL the reference details at left...
6.	Ipratropium (Ipratropium Bromide)FDA LinkGeneric 04/01/1981 - "Ipratropium nasal spray: a new treatment for rhinorrhea in the common cold." 12/01/1992 - "A double-blind, placebo-controlled study of the safety and efficacy of ipratropium bromide nasal spray versus placebo in patients with the common cold." 05/01/1995 - "A dose-response study of the efficacy and safety of ipratropium bromide nasal spray in the treatment of the common cold." 04/01/1981 - "In a placebo-controlled group comparative trial, 80 micrograms of ipratropium were taken as a nasal spray 4 times daily for 1 wk by 40 adults with spontaneously occurring common colds. " 06/01/1997 - "In conclusion: (1) during the first days of a common cold about 60% of the nasal discharge is a reflex-mediated product from nasal glands; (2) this type of secretion is predominantly watery; and (3) ipratropium bromide can reduce watery rhinorrhoea in the common cold, but a lower dose is required in order to avoid side effects." Order ALL the reference details at left...
7.	Histamine Antagonists (Antihistamines)IBA 04/01/1996 - "OBJECTIVE: To determine if antihistamines provided clinically significant relief from the symptoms of the common cold. " 01/01/2009 - "SELECTION CRITERIA: Randomised, placebo-controlled trials on treatment of common cold with antihistamines, used either singly or in combination, in adults or children. " 01/01/2003 - "SELECTION CRITERIA: Randomised, placebo-controlled trials on treatment of common cold with antihistamines, used either singly or in combination, in adults or children. " 01/01/2009 - "OBJECTIVES: To assess in patients with a common cold the effects of antihistamines in alleviating nasal symptoms, or the shortening the duration of illness. " 01/01/2009 - "BACKGROUND: Although antihistamines are prescribed in large quantities for the common cold, there is little evidence as to whether these drugs are effective. " Order ALL the reference details at left...
8.	Pseudoephedrine FDA LinkGeneric 08/01/2002 - "[An open label multi-center clinical trial to evaluate the efficacy of compound pseudoephedrine [corrected] hydrochloride sustained release capsules in patients with nasal symptoms associated with common cold]" 02/01/1999 - "A placebo-controlled double-blind randomized trial was carried out to assess the efficacy of pseudoephedrine in relieving nasal congestion in the common cold. " 02/01/1999 - "The effects of oral pseudoephedrine on nasal patency in the common cold: a double-blind single-dose placebo-controlled trial." 01/01/2008 - "Pseudoephedrine hydrochloride (PEH) is a sympathomimetic agent that is widely used in common cold disease in children. " 07/01/2007 - "Clinical trial of 3 days of treatment with oral pseudoephedrine for the common cold in the southern hemisphere." Order ALL the reference details at left...
9.	Terfenadine (Seldane)IBA 03/01/1988 - "This study evaluated the short-term efficacy of oral terfenadine (Seldane) in the treatment of the common cold. " 01/01/1988 - "Efficacy of terfenadine in the treatment of common cold. " 10/01/1992 - "The mean plasma VIP concentration of the subjects with common cold was slightly higher than that of the healthy subjects before and after terfenadine administration, with no significant difference." 12/01/1991 - "Terfenadine was found to be ineffective in the treatment of the signs and symptoms of the common cold." 12/01/1991 - "Evaluation of oral terfenadine for treatment of the common cold." Order ALL the reference details at left...
10.	Zinc Acetate FDA Link 12/01/2000 - "Are zinc acetate lozenges effective in decreasing the duration of symptoms of the common cold?" 08/15/2000 - "OBJECTIVE: To test the efficacy of zinc acetate lozenges in reducing the duration of symptoms of the common cold. " 05/15/2001 - "Elimination of efficacy by additives in zinc acetate lozenges for common colds." 08/15/2000 - "Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. " 10/01/1997 - "It is concluded that: prospective efficacy of zinc lozenges can be predicted based upon readily determined ZIA factors and ZIAs; chemically different zinc lozenge formulations having greatly different ZIAs resulted in greatly differing results in clinical trials; mast cell granule-derived Zn2+ ions are the foundation of the primary immune system; and high ZIA zinc acetate lozenges are beneficial for common colds." Order ALL the reference details at left...

Therapies and Procedures

1.	Homeopathy 06/01/2001 - "METHODS: The methodological quality of 207 randomized trials collected for five previously published systematic reviews on homeopathy, herbal medicine (Hypericum for depression, Echinacea for common cold), and acupuncture (for asthma and chronic headache) was assessed using a validated scale (the Jadad scale) and single quality items. " 02/26/2004 - "[Homeopathy of classical medicine: your prescription for cough, common cold, hoarseness?]" 10/16/1992 - "This was performed for controlled clinical trials on the efficacy of three interventions: homoeopathy, ascorbic acid for common cold, and ginkgo biloba for intermittent claudication and cerebral insufficiency. " 10/16/1992 - "Searches for controlled trials of homoeopathy, ascorbic acid for common cold and ginkgo biloba for cerebral insufficiency and intermittent claudication." 09/17/1994 - "This article gives examples of systematic reviews on vitamin C and the common cold, pyridoxine against the premenstrual syndrome, homeopathy, and physiotherapy." Order ALL the reference details at left...
2.	Cryotherapy (Therapy, Cold) 07/01/1992 - "Efficacy of cryotherapy in vernal catarrh." 10/01/1999 - "We briefly review the physiology of cold exposure, the spectrum and prevention of common cold-induced injuries (especially in athletes participating in outdoor sports), and the potentially harmful side effects of localized cryotherapy. " 01/01/1999 - "The scientific basis for zinc treatment of the common cold is debatable, and clinical trials of zinc cold therapy have produced conflicting results. " Order ALL the reference details at left...
3.	Injections 11/01/2009 - "Third, Chinese herbal injections should be used only in cases involving severe disease or to rescue patients in critical condition; they should not be used to treat mild, relatively innocuous diseases, such as common colds and upper respiratory tract infections, given the risk of doing harm. " 11/01/2009 - "Comments on serious anaphylaxis caused by nine Chinese herbal injections used to treat common colds and upper respiratory tract infections." 07/01/2002 - "CONCLUSIONS: Antibiotics and injections were frequently prescribed for mild common colds in Korea. " 12/01/1997 - " Of concern, however, was the high frequency of incorrect responses for the following items: malaria is caused by eating unripe sweet sorghum (33.7%); one is predisposed to malaria by attacks of common cold (56.6%); chloroquine injections are more effective for treatment than are tablets (28.6%); malaria can be treated with the beverage Aradaib (22.6%); iv fluids are essential for treatment of a malaria attack (36.7%); and malaria can be prevented by taking multivitamins (48.0%). " Order ALL the reference details at left...
4.	Induced Hyperthermia (Thermotherapy) 05/13/1989 - "Local hyperthermia benefits natural and experimental common colds." 08/01/1992 - "Local hyperthermia is effective in reducing the symptoms of the common cold and perennial and seasonal allergic rhinitis, nasal patency also being improved in rhinitis. " 10/01/1993 - "Local hyperthermia or inhalation of heated water vapor is often recommended as a home remedy for various nasal disorders such as the common cold and allergic rhinitis. " Order ALL the reference details at left...
5.	Aftercare (After-Treatment) 06/01/1998 - "After treatment, rhinoviruses were cultured more often in the FP treatment group (37% vs 14%, p < 0.001), but this had no effect on the symptoms of common cold. " 10/09/1977 - "A patient with a toxic adenoma, already reduced in size by TSH, presented on the third day after treatment of a common cold by phenylpropanolomine, a severe pain in the thyroid gland. " 03/01/2003 - "RESULTS: After treatment, there was much better improvement in symptom score (2.4 +/- 0.9 vs 3.1 +/- 0.9, P < 0.01), symptomatic days due to rhinitis (4.0 +/- 1.2 d/week vs 1.9 +/- 0.9 d/week, P < 0.001), episode of common cold symptom (0.8 +/- 0.5 time vs 1.1 +/- 0.4 time, P < 0.001), average doses of inhaled beta(2) agonist as rescue medication (2.6 +/- 0.9 puff/week vs 3.7 +/- 0.8 puff/week, P < 0.001) and bronchial responsiveness (P < 0.05) in Loratadine group as compared with the control group. " Order ALL the reference details at left...

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