Combined Modality Therapy

Subscribe to Selected New Research on Combined Modality Therapy

1509 relevant articles (147 outcomes, 214 trials/studies) found for this Therapy

Description: The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.

Also Known As:

Combined Modality Therapies; Modality Therapies, Combined; Modality Therapy, Combined; Multimodal Treatments; Therapies, Combined Modality; Treatment, Multimodal; Treatments, Multimodal; Multimodal Treatment; Therapy, Combined Modality

Relationship Network

Therapy Context: Research Results

Therapeutics: 5215

Combined Modality Therapy: 1509

Adjuvant Chemotherapy: 6163

Photochemotherapy: 5018

Neoadjuvant Therapy: 1364

Adjuvant Radiotherapy: 1263

Radioimmunotherapy: 1263

Salvage Therapy: 1086

Electroacupuncture: 596

Experts

1.	Minsky, Bruce D: 20 articles (03/2008 - 03/2002)
2.	Guillem, Jose G: 9 articles (01/2007 - 01/2003)
3.	Paty, Philip B: 8 articles (03/2008 - 08/2003)
4.	Wong, W Douglas: 7 articles (03/2008 - 08/2003)
5.	Shia, Jinru: 5 articles (03/2008 - 03/2004)
6.	Ilson, David H: 5 articles (10/2006 - 08/2002)
7.	Choy, Hak: 5 articles (11/2005 - 12/2003)
8.	Saltz, Leonard: 5 articles (06/2005 - 01/2003)
9.	Kelsen, David P: 5 articles (07/2004 - 03/2002)
10.	Choy, H: 5 articles (08/2001 - 01/2001)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2008 - "PURPOSE: Although most patients with anal canal cancer are cured with sphincter-preserving, nonsurgical, combined-modality therapy, those with large tumors and lymph node involvement have a poor prognosis" 12/01/2001 - "OBJECTIVE: Because the long-term survival of children with cancer has dramatically improved because of multimodal treatment strategies, intensive care medicine has become more relevant for these patients" 06/01/1999 - "With the consistent use of effective multimodal treatment, including combination chemotherapy, surgery and radiotherapy, the prognosis for all types of childhood cancer has dramatically improved over the last 25 years and the current 5-year survival rate is about 60-98%" 02/01/1991 - "A review of the literature of normal tissue effects after combined treatment with drugs and radiation has lead to the following general conclusions: a) The sequence and timing of the two agents have a marked influence on the extent of normal tissue damage, with the most damage occurring when simultaneous drug and irradiation are given within a few days of each other; b) Separation of the two modalities can lead to an improved therapeutic gain since tumor effects are less strongly dependent on the interval between drug and X rays; and c) Chemotherapy can markedly alter the time of expression of radiation damage, particularly in slowly dividing normal tissues, where more rapid expression of injury occurs after combined modality therapy" 12/15/2000 - "Patients with early-stage disease are often cured with surgery or radiotherapy but are at high risk for second primary tumor (SPT) development (Lippman and Hong, [1989]), and the majority of patients present with advanced disease, for which the outcomes have not markedly improved despite advances in combined-modality therapy (Vokes et al., [1993])" Order ALL the reference details at left...
2.	Hodgkin Disease (Hodgkin's Disease) 09/01/1977 - "The use of combined modality therapy (irradiation and combinations of drugs) in the treatment of Hodgkin's disease has produced a significant improvement in survival, during which most patients lead an active and productive life" 03/19/1996 - "In patients with Hodgkin's disease presenting with massive mediastinal involvement the efficacy of combined modality therapy has been proven by all research groups" 01/15/1985 - "Combined modality therapy was used in an attempt to increase the complete remission rate and survival of previously untreated patients with Hodgkin's disease" 11/01/1991 - "These results suggest that combined modality therapy may be beneficial for some patients with Hodgkin's disease and that age must be carefully considered in interpreting the results of clinical trials in Hodgkin's disease." 02/01/1993 - "We believe that combined-modality therapy is effective in the treatment of osseous involvement in Hodgkin's disease." Order ALL the reference details at left...
3.	Small Cell Carcinoma (Small Cell Lung Cancer) 04/07/1993 - "PURPOSE: The purpose of this phase II trial was to determine the disease-free and overall survival, toxic effects, and relapse patterns in patients with limited small-cell lung cancer who were in partial or complete response to first-line conventional-dose chemotherapy and then received intensive systemic combined modality therapy" 03/01/1999 - "Over the past few years there have been numerous schedules of combined modality therapy proposed as being useful in the management of inoperable non-small cell lung cancer (NSCLC)" 10/01/1998 - "PURPOSE: Combined modality therapy for non-small-cell lung cancer (NSCLC) has produced promising results" 09/01/2007 - "OBJECTIVE: To investigate the efficacy of combined modality therapy for small cell lung cancer (SCLC) patient with limited stage disease (LD)" 05/01/2002 - "Locally advanced or unresectable stage III non-small-cell lung cancer (NSCLC) patients treated with combined-modality therapy with chemotherapy plus thoracic radiation have improved survival compared to those treated with radiotherapy alone" Order ALL the reference details at left...
4.	Rectal Neoplasms (Rectal Cancer) 08/01/2006 - "A pathologic complete response of rectal cancer to preoperative combined-modality therapy results in improved oncological outcome compared with those who achieve no downstaging on the basis of preoperative endorectal ultrasonography." 07/01/2003 - "Despite the routine use of adjuvant chemoradiation for curatively resected stage II and III rectal cancer a significant percentage of patients ultimately fail locally and/or distally; this underscores the need for continued improvement in the efficacy of combined-modality therapy and quality of rectal cancer resection" 09/01/1988 - "Combined modality therapy is a safe and effective regimen for those rectal tumors in the high risk category." 08/01/2005 - "These results suggest that FDG-PET is superior to CT and MRI in predicting response to preoperative multimodal treatment of locally advanced primary rectal cancer." 01/01/2004 - "Studies have supported the use of combined modality therapy as standard adjuvant care for clinical T3 rectal cancer in the preoperative setting and for patients with T3 and/or N1/N2 disease in the postoperative setting, wtih improved rates of sphincter preservation, recurrence and overall survival." Order ALL the reference details at left...
5.	Neoplasm Metastasis (Metastasis) 05/01/1997 - "The multimodal treatment including gamma-knife radiosurgery has produced complete remission of multiple brain metastases for 21 months with good quality of life" 11/01/2006 - "Despite improved survival with combined modality therapy, local-regional recurrences and the development of distant metastases are still problematic" 06/01/2008 - "Combined modality therapy will control most nodal metastases (even for patients with advanced nodal disease)" 03/25/2008 - "The median survival time after metastasis of the 8 cases given multimodal treatment was 14.0 months, 7.5 months longer than that of the 4 cases untreated (6.5 months, P = 0.09)" 06/01/2007 - "Role of repeated hepatectomy in the multimodal treatment of hepatic colorectal metastases." Order ALL the reference details at left...

Related Drugs and Biologics

1.	pemetrexed (MTA)
2.	Doxorubicin (Adriamycin)
3.	Paclitaxel (Taxol)
4.	Cisplatin (Platino)
5.	Bleomycin (Blenoxane)
6.	Cytostatic Agents
7.	Proteins (Proteins, Gene)
8.	First Step
9.	valdecoxib (Bextra)
10.	Vinblastine (Vinblastine Sulfate)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Combination Drug Therapy (Combination Chemotherapy)
3.	Neoadjuvant Therapy
4.	Adjuvant Chemotherapy
5.	Immunotherapy

Best Treatments:
Research Summary Report
on Neoplasms

CureHunter Patient-Physician Summary Reports collect in one document all the medications ever reported in the US National Library of Medicine—1949 to the present—to be effective against your target disease. CureHunter research summary reports will vary in length from 25 to 250 pages. Analytic charts allow you and your physicians to see at a glance your medication options—including new, promising, off-label and experimental all rated for clinical efficacy.

Free Updates for 1 Year
All 18510 Outcomes
Top 200 Key Drugs and Biologics
Top 50 Key Therapies and Procedures
Detailed History Charts
Full Research Reference Details
Sample PDF Report on Psoriasis >>

Price:

$24.00 & Delivery via PDF download
updates for 1 year

Research Interface

Rapidly retrieve summaries of all the evidence for any disease in seconds. Save hours of search and analysis time. CureHunter is unlike any "search engine" you have ever used. Where standard "search engines" produce lists of links, CureHunter quantifies evidence, extracts it from the literature and calculates a result you can use to immediately facilitate evidence based decision making in Real Clinical Time.

Unlimited Disease, Drug and Therapy Search
2 clicks from Disease to Drug to Evidence
Trial References
All the Positive Outcomes
Detailed Relationship Timeline Charts
Full Article Reference Details
Includes Mobile Interface Subscription
One-click to FDA Products/Patents
Request Institution License Details >>

Price:

$490.00 access via web interface
1 year subscription

Proceed to Checkout >>

Mobile Interface

Retrieve summaries of all the evidence for any disease from your Mobile Phone or PDA. Accelerate decision making in the field. Speed up your study of new drug and disease domains. Refresh your knowledge on the road.

Access from any web enabled PDA or Phone
Trial references
All the Positive Outcomes
Drug and Therapy searches
Full Article Reference Details
Try Mobile Interface >>

Price:

$45.00 access via "curehunter.com/m"
1 year subscription

Proceed to Checkout >>