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Collagen

A polypeptide substance comprising about one third of the total protein in mammalian organisms. It is the main constituent of SKIN; CONNECTIVE TISSUE; and the organic substance of bones (BONE AND BONES) and teeth (TOOTH).
Also Known As:
Avicon; Avitene; Collagen Felt; Collagen Fleece; Collagenfleece; Collastat; Dermodress; Microfibril Collagen Hemostat; Pangen; Zyderm; alpha-Collagen; Collagen Hemostat, Microfibril; alpha Collagen; Collagens
Networked: 29316 relevant articles (916 outcomes, 2707 trials/studies) for this Bio-Agent, Comments

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Bio-Agent Context: Research Results

Experts

1. Zhang, Wei: 36 articles (09/2014 - 04/2002)
2. Holmdahl, Rikard: 32 articles (08/2014 - 01/2002)
3. Risteli, Juha: 32 articles (01/2013 - 07/2002)
4. Sener, Göksel: 32 articles (04/2012 - 09/2004)
5. Gedik, Nursal: 32 articles (09/2008 - 09/2004)
6. Bonaldo, Paolo: 30 articles (10/2014 - 12/2003)
7. Samuel, Chrishan S: 27 articles (11/2014 - 10/2002)
8. Heemskerk, Johan W M: 26 articles (06/2014 - 08/2002)
9. Kymionis, George D: 23 articles (10/2014 - 05/2009)
10. Díez, Javier: 23 articles (10/2014 - 05/2002)

Related Diseases

1. Wounds and Injuries (Trauma)
2. Fibrosis (Cirrhosis)
3. Cicatrix (Scar)
4. Inflammation
01/01/1987 - "These results show that DP could be effective in preventing damage of chondrocytes and inhibition of collagen biosynthesis in them, phenomena important in cartilage destruction induced by a chronic immunological inflammation."
12/01/2013 - "This was associated with a significant reduction in post-operative proliferation, inflammation and angiogenesis during the first post-operative days after surgery, and with a decrease in collagen deposition at later stages. "
03/01/2013 - "Group V (12 weeks) showed significantly improved collagen organization versus other treatment groups; there was no difference in collagen organization in Group I versus V. In summary, increased cellularity, inflammation, vascularity, and collagen organization were present at 3 weeks; increased collagen organization at 12 weeks in Group V provides evidence for improved healing with cells. "
12/01/2012 - " Treatment significantly improved the clinical performance, cell, collagen and tissue maturation, tissue alignment and remodeling, ultimate strength, stiffness, maximum stress, and dry weight content and decreased the tendon diameter, inflammation, adhesions and degeneration of the injured treated tendons compared to the injured control ones. "
03/01/2010 - "The results demonstrated significant differences between G2 and G3, and between G2 and G4, at both 3 days and 7 days, with regard to acute inflammation scores; G1 and G2 showed significant differences when compared with G4 at 3 days, with regard to neo-angiogenesis scores; G1 and G2 were statistically different from G3 and G4 at both 3 days and 7 days, with regard to re-epithelization scores; G2 showed statistically significant differences when compared with G3 and G4 with regard to collagen fiber scores at 7 days. "
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5. Arthritis (Polyarthritis)

Related Drugs and Biologics

1. Riboflavin (Vitamin B2)
2. Hydroxyproline (4 Hydroxyproline)
3. Bleomycin (Blenoxane)
4. Thrombin
5. Fibronectins (Fibronectin)
6. Messenger RNA (mRNA)
7. Antibodies
8. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
9. Transforming Growth Factor beta (TGF-beta)
10. Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)

Related Therapies and Procedures

1. Transplants (Transplant)
2. Lasers (Laser)
3. Injections
4. Sutures (Suture)
5. Transplantation (Transplant Recipients)

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