Coagulants

08/01/2007 - "Conclusive evidence to support the use of anti-coagulant treatment or AT concentrates for primary prevention is lacking, as is evidence for the efficacy of AT concentrates in the management of established thrombosis. "
01/01/2021 - "Identifying the leading factors to a pro-coagulant environment in each case-mechanical or biochemical-could help define improved strategies for thrombosis prevention tailored for each patient."
05/27/2022 - "In this study, a more accurate model for thrombus assessment was constructed by integrating parameters such as shear stress, residence time and coagulant factors, so as to accurately assess the probability of thrombosis in three clinical VADs. "
01/01/2020 - "The role of red blood cell-derived MPs is more intriguing; they have been proposed as markers of ongoing thrombosis in patients with ACS, while previous studies have shown that they have anti-coagulant properties in healthy individuals. "
01/01/2006 - "In future studies with ex vivo dose titration assessment of pro-coagulant components mixed with blood from a patient suffering from compromised haemostasis, observation of a significantly shortened clot initiation concomitant with a distinctly accelerated clot propagation is likely to indicate an increased risk of thrombosis."

03/06/2012 - "Conversely, although cationic coagulant aids were the most effective in reducing OSPW turbidity, the application of cationic coagulant aids promoted the adsorption of foulants on membrane surfaces."
12/15/2021 - "The increase of coagulant aids dosage improved the effect of adsorption and sweep flocculation significantly. "
01/01/2014 - "The study showed that the application of SA as coagulant aids resulted in larger and stronger flocs, which would improve treatment efficiency of the coagulation process. "
02/18/1988 - "Japanese AIDS scandal over trials and marketing of coagulants."
12/15/2021 - "Mechanism of coagulation was studied by scanning electron microscope (SEM), Fourier transform infrared spectroscope (FTIR), X-ray photoelectron spectroscopy (XPS), and the results illustrated that when only PAC existed or the dosage of coagulant aids was low, double layer compression was the main principle. "

06/19/2023 - "CT-001 corrected APC pathway-mediated coagulopathic conditions in preclinical studies and could be a potentially safe and effective pro-coagulant agent for addressing APC-mediated bleeding. "
01/01/2017 - "Conclusion The PRO-RBDD study suggests a FXIII coagulant activity level of 15 IU dL-1 as a target to start prophylaxis in order to prevent major bleedings, such as central nervous system or gastrointestinal tract hemorrhages."
01/01/2006 - "A series of studies were conducted to validate the feasibility of the model to illustrate hypocoagulation in various bleeding disorders and its usefulness in detecting the haemostatic effect of pro-coagulants by ex vivo titration experiments. "
03/01/1992 - "Such a trial should include careful family and clinical bleeding histories plus measurement of a platelet count, BT, coagulant FVIII and vWF levels, RCoF activity, and vWF multimer analysis. "
11/30/2023 - "The incidence of post-ESD bleeding taking DOAC was high, especially in aged patients and with high anti-coagulant effects. "

11/01/2018 - "A total of 180 patients who underwent the laparoscopic surgery for the gynecological tumors in this hospital between January 2015 and December 2017 were enrolled in this study, and according to the anti-coagulant procedure, they were divided into two groups, i.e. "
01/01/2016 - "Studies on the Tumor Vasculature and Coagulant Microenvironment."
01/05/2010 - "These data highlight the linked pro-coagulant and immunoinflammatory pathways in the multimodal management of oesophageal cancer, and suggest that the duration of current standard thromboprophylaxis regimens warrants further study."
03/01/2006 - "Large registries offer an opportunity to study the risk of VT in large cohorts of cancer patients, which is essential in decisions on prophylactic anti-coagulant treatment. "
01/01/2023 - "Likewise, the therapeutic approach with anti-coagulants in leukemic patients is inferred from guidelines originally developed in the solid cancer setting and clear recommendations in the thrombocytopenic population are limited. "

06/01/2020 - "Limited information is available, however, on its coagulant effect in acquired hemophilia A (AHA). "
06/01/2020 - "Plasma-derived factors VIIa and X mixtures (Byclot®) significantly improve impairment of coagulant potential ex vivo in plasmas from acquired hemophilia A patients."
01/01/2019 - "Thirty-three hemophilia A patients (FVIII coagulant activity [FVIII:C] ≤2 IU/dL) without inhibitors underwent 85 FVIII single-dose (21.4-51.8 IU/kg) PKs with different FVIII concentrates. "
01/01/2019 - "Here, we review the current role of FVIII coagulant (FVIII:C) in haemophilia A management and emerging evidence for the role of FVIII across multiple systems, including the cardiovascular system, angiogenesis and maintenance of bone health. "
01/01/2015 - "Acquired coagulant factor VIII deficiency induced by Bacillus anthracis lethal toxin in mice."