|1.||Congenital Abnormalities (Deformity)
|2.||Cleft Palate (Palate, Cleft)
|4.||Neural Tube Defects (Exencephaly)
|1.||Shi, Bing: 20 articles (06/2015 - 12/2005)|
|2.||Carinci, Francesco: 15 articles (01/2016 - 10/2003)|
|3.||Murray, Jeffrey C: 14 articles (05/2014 - 05/2003)|
|4.||Pezzetti, Furio: 13 articles (04/2012 - 10/2003)|
|5.||Mulliken, John B: 12 articles (07/2015 - 08/2002)|
|6.||Shaw, Gary M: 12 articles (06/2014 - 10/2004)|
|7.||Scapoli, Luca: 11 articles (01/2016 - 06/2004)|
|8.||Martinelli, Marcella: 9 articles (01/2016 - 06/2004)|
|9.||Chen, Philip Kuo-Ting: 9 articles (01/2016 - 11/2011)|
|10.||Song, Tao: 9 articles (11/2015 - 12/2008)|
05/01/2012 - "The presurgical nasoalveolar molding technique improved nasal tip projection and alar cartilage depression and decreased partially columella deviation before rhinocheiloplasty in South American unilateral cleft lip/palate patients."
12/01/2014 - " results show that this modification has improved the alar contour and symmetry in patients undergoing primary cleft-lip nasal repair. "
06/01/2001 - "The purpose of this study was to audit the process and outcome in terms of nasal-tip symmetry of the first 20 patients with unilateral complete cleft lip and palate treated by the Pigott alar leapfrog primary nasal correction in the early 1970s and followed for 20 years. "
05/01/1998 - "This study was to explore the pathological action of the adjacent connective tissues of alar cartilage in unilateral cleft lip nose. "
03/01/2015 - "Analysis of alar balance in secondary cleft lip with Z-plasty technique of nasal cartilage."
|2.||Folic Acid (Vitamin M)FDA LinkGeneric
11/01/2013 - "In conclusion, this study presents several lines of evidence indicating that periconceptional folic acid in the Northern Netherlands is associated with an increased risk of clefts, in particular of cleft lip/alveolus. "
01/01/2012 - "This study will assess the effect of 4 mg and 0.4 mg doses of folic acid, taken on a daily basis during preconception and up to 3 months of pregnancy by women who are at risk of having a child with nonsyndromic cleft lip with/without palate (NSCL/P), on the recurrence of NSCL/P. "
07/01/2001 - "Additional studies are necessary on the effect of folate in different species, also taking cleft lip and CP into consideration."
03/27/2014 - "But, the data regarding the folic acid status in children with cleft lip/palate is hardly evaluated in depth. "
01/01/2013 - "Oral folic acid supplementation decreases palate and/or lip cleft occurrence in Pug and Chihuahua puppies and elevates folic acid blood levels in pregnant bitches."
|3.||Bupivacaine (Bupivacaine Hydrochloride)FDA LinkGeneric
09/01/2015 - "In this randomized, placebo-controlled trial, we enrolled 110 children (5 months to 6 years of age), who were scheduled for cleft lip surgery, and randomized them to the following two groups: Group S and Group B, where 1.5 ml saline (Group S) or 1.5 ml 0.25% bupivacaine (Group B) were administered in the infraorbital foramen. "
01/01/1991 - "We studied the efficacy of a 0.5% bupivacaine infraorbital nerve block as post-operative analgesia in a random, prospective, double blind manner in children undergoing cleft lip repair. "
03/01/1999 - "This study was designed to compare the efficacy and duration of effect of 0.125% bupivacaine given preoperatively as a bilateral infraorbital nerve block with peri-incisional infiltration of the same local anaesthetic for postoperative analgesia in cleft lip repair. "
03/01/1999 - "We conclude that infraorbital nerve block with 0.125% bupivacaine provides better and more prolonged analgesia than peri-incisional infiltration in cleft lip repair."
07/01/2009 - "The objective of this study was to evaluate the effectiveness of bilateral extraoral infraorbital nerve block with 0.25% bupivacaine administered at the end of surgery in postoperative pain relief after cleft lip repair. "
|4.||sevoflurane (Ultane)FDA LinkGeneric
01/01/2015 - "100 infants (1~3 years old) with cleft lip and palate and ASA classification I~II were randomized into two groups, a sevoflurane concentration decreasing expelling group (group n = 50 cases) and a low fresh gas flow expelling group (group D = 50 cases). "
03/01/2014 - "The effect of sevoflurane on developing A/J strain mouse embryos using a whole-embryo culture system--the incidence of cleft lip in culture embryos."
09/01/2015 - "The objective of this prospective randomized, placebo-controlled trial was to determine whether infraorbital nerve block reduces EA in children undergoing repair of cleft lip after sevoflurane. "
09/01/2015 - "The effect of infraorbital nerve block on emergence agitation in children undergoing cleft lip surgery under general anesthesia with sevoflurane."
09/01/2015 - "In children undergoing cleft lip repair surgery, infraorbital nerve block at the beginning of surgery significantly decreased the incidence of EA and the duration of EA, and provided satisfactory postoperative analgesia without delaying the time to extubation with sevoflurane anesthesia."
11/01/1990 - "This report gives credence to the ease with which a cleft lip repair that gives reproducible good results can be taught and learned even by plastic surgeons with limited experience. "
09/01/1997 - "The 58 patients participating in the study had a history of complete unilateral cleft lip and palate, all of which were repaired by the same plastic surgeon. "
01/01/1987 - "Over the past 28 years, a series of studies at the West Midlands Regional Plastic Unit has compared the maxillary arches at birth and 4 months of 30 normal children and two groups of children with unilateral cleft lip and palate, one of which had presurgical maxillary orthopaedic treatment and the other which did not. "
01/01/2016 - "The results may aid plastic surgeons in performing cleft-lip correction surgery."
06/01/2015 - "Cleft lip and palate patients assessed using the scoring system proposed by Prahl et al, a 5-point ordinal scale, and the scoring system proposed by Asher-McDade et al by 6 judges, 3 orthodontists, and 3 plastic surgeons. "
01/01/2015 - "No significant differences were found in the mandible (Co-Gn) of the control group and individuals with cleft lip and palate (P = 1.000). "
01/01/2015 - "Individuals with cleft lip and palate had a significantly shorter maxillary length (Co-A) in comparison to the control group (P < 0.001). "
04/01/2012 - "FHN-A, FHN-B, FH-NA, FH-NB, and Co-Me were significantly smaller in the cleft lip and palate groups than in the corresponding control groups. "
12/01/2004 - "We show that adult A/WySnJ mice that do not express cleft lip exhibit decreased morphological integration of the cranium and that the co-ordination of overall shape and size variation is disrupted compared with both C57BL/6J mice and the F1 cross. "
01/01/2004 - "One had right-sided cleft lip, while the co-twin had left-sided cleft lip. "
|7.||Fentanyl (Sublimaze)FDA LinkGeneric
07/01/2012 - " To investigate whether perioperative fentanyl use for cleft lip and palate surgery varies between children of three different geographic regions. "
02/01/2007 - "Eighty-two children aged 3 months to 10 years undergoing cleft lip repair were prospectively randomized to one of two groups: bilateral infraorbital nerve block (Group B), or i.v. fentanyl (Group F). "
02/01/2007 - "The efficacy of analgesia with bilateral infraorbital nerve block and intravenous (i.v.) fentanyl were compared for cleft lip surgery in children. "
02/01/2007 - "A comparison of bilateral infraorbital nerve block with intravenous fentanyl for analgesia following cleft lip repair in children."
04/07/2009 - "Multimodal analgesic regimen of infiltration of local anesthetic at surgical site and rectal paracetamol and intravenous fentanyl provides sufficient analgesia, minimizes the incidence of agitation after general anesthesia in cleft lip and/or palate surgery for children, increases the speed of referring patients in PACU, and ensures the safety of the postanaesthetic patients."
|8.||2-benzyl-3-formylpropanoic acid (BFP)IBA
01/01/2015 - "The current study is the first case report that shows the use of free graft of BFP in oronasal fistula after cleft lip and palate surgery and aimed to discuss the promising results of this surgical technique, suggesting it as a treatment option for anterior maxillary defects, when properly indicated. "
09/01/2013 - "Lower concentrations of B-vitamin subgroups in the serum and amniotic fluid correlate to cleft lip and palate appearance in the offspring of A/WySn mice."
05/01/2000 - "Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and risk of nonsyndromic cleft lip."
11/16/1998 - "Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip."
04/01/1964 - "NO ASSOCIATION OF EMOTIONAL STRESS OR VITAMIN SUPPLEMENT DURING PREGNANCY TO CLEFT LIP OR PALATE IN MAN."
10/01/2013 - "We investigated the association of maternal periconceptional intake of vitamin supplements and dietary nutrients with risk of developing cleft palate (CP) and cleft lip with or without cleft palate (CLP). "
04/03/2012 - "At a load dosage of 1 µg/kg and a maintenance dosage of 0.75 µg × kg(-1)× h(-1), dexmedetomidine shows excellent effects on the recovery period of cleft lip and palate repairing in pediatric patients. "
04/03/2012 - "[Effect of dexmedetomidine on postoperative analgesia and sedation in pediatric patients undergoing cleft lip and palate repair]."
04/01/2008 - "Postoperative management of cleft lip repair using dexmedetomidine in a child with bidirectional superior cavopulmonary shunt."
04/03/2012 - "To explore the effect of different doses of dexmedetomidine on the sedation of recovery period and the postoperative early pain scores in pediatric patients undergoing cleft lip and palate repair. "
05/20/2014 - "A single intravenous dose of dexmedetomidine is effective in reducing emergence agitation and coughing, shortening length of PACU stay and improving the quality of recovery period after sevoflurane anesthesia in pediatric patients undergoing cleft lip and palate repair."
|1.||Nerve Block (Nerve Blocks)
05/01/1995 - "Infraorbital nerve block in neonates for cleft lip repair: anatomical study and clinical application."
01/01/2011 - "45 children between the age group 5 - 60 months undergoing cleft lip surgery randomly allocated into 3 groups of 15 each received bilateral intraoral infraorbital nerve block with 0.75ml of solution. "
05/01/2006 - "Infraorbital nerve blocks are performed in children undergoing cleft-lip surgery and endoscopic sinus surgery. "
05/01/1995 - "Infraorbital nerve block in neonates is not well described although it has been suggested that bilateral infraorbital nerve block is the local analgesic technique of choice for early repair of cleft lip. "
03/01/1999 - "Bilateral infraorbital nerve block is superior to peri-incisional infiltration for analgesia after repair of cleft lip."
09/01/2014 - "This study describes the planning process for a three-dimensional (3D) model of a nasoalveolar bone graft in patients with unilateral cleft lip and palate. "
04/01/2014 - "The aim of this study was to assess the objective and subjective morbidity after reconstruction of alveolar bone defects with mandibular symphyseal bone grafts in patients with cleft lip and palate. "
12/01/2011 - "The aim of the present study was to test the agreement between a new developed clinical examination method and two commonly used radiographic scales (Bergland and Chelsea) for assessing alveolar bone graft outcomes in the cleft lip and palate patients. "
07/01/2011 - "The purpose of this study was to describe the clinical and three-dimensional (3D) outcomes following secondary correction of bilateral cleft lip and nose by reverse-U incision, nasal tip cartilage graft, and medial-upward advancement of bilateral nasolabial components with vestibular expansion with a free mucosal graft. "
05/01/2011 - "Thirteen patients, 8 to 13 years old, with cleft lip and palate who underwent alveolar bone graft at Srinagarind Hospital and Faculty of Dentistry of Khon Kaen University were recruited into the study to test the agreement between two sets of data: (1) clinical examination scores and an expert's clinical judgment, (2) clinical and radiographic examination scores (Bergland and Chelsea scales). "
09/01/2003 - "Nasal alveolar molding is used effectively to reshape the nasal cartilage and mold the maxillary arch before cleft lip repair and primary rhinoplasty. "
12/01/2014 - "The purpose of this study was to determine patient satisfaction after rhinoplasty in patients born with a cleft lip compared with outcome assessment by professionals, and to assess the impact of the procedure on appearance-related distress and generic quality of life. "
06/01/2010 - "The purpose of this study was to evaluate stereophotogrammetry as a 3D method to document volumetric changes of the nose in patients with a cleft lip (CL) or cleft lip and palate (CLP) after secondary open rhinoplasty. "
09/01/2009 - "Results of a prospective anthropometric and functional study about aesthetics and nasal respiration after secondary rhinoplasty in cleft lip and palate patients."
12/01/2006 - "Primary rhinoplasty was carried out concurrently for both study groups while undergoing unilateral cleft-lip repair. "
02/01/2014 - "Survey of analgesia for cleft lip and palate repair in the UK and Republic of Ireland."
09/01/2003 - "Analgesia for cleft lip and palate: comment on Takemura et al."
03/01/1999 - "Bilateral infraorbital nerve block is superior to peri-incisional infiltration for analgesia after repair of cleft lip."
07/01/2009 - "Bilateral extraoral, infraorbital nerve block administered at the end of surgery provides satisfactory analgesia with high parental satisfaction and lower complication rates and reduces rescue analgesic consumption in patients undergoing repair of cleft lip."
04/07/2009 - "To investigate the effects of multimodal analgesia on analgesia and sedation during emergence of general anesthesia for cleft lip and/or palate surgery pediatric patients. "
|5.||Bone Transplantation (Bone Grafting)
10/01/2014 - "To quantify the treatment outcome of secondary alveolar bone grafting (SABG) in individuals with unilateral cleft lip and palate using cone beam computed tomography (CBCT) and to reveal needs for improvement in surgical technique. "
11/01/2010 - "Alveolar bone grafting appears to have improved radiographic outcomes when compared with the CSAG report following the re-organisation of surgical services for children with cleft lip and/or palate."
01/01/2016 - "The aim of this study was to compare the outcomes of primary gingivoperiosteoplasty and secondary alveolar bone grafting in patients with unilateral cleft lip and palate. "
10/01/2015 - "The purpose of this study was to investigate the effect of secondary alveolar bone grafting (SABG) on the maxillary growth in patients with unilateral (UCLP) and bilateral cleft lip and palate (BCLP). "
12/01/2014 - "The objective of the present study was to examine the timing and hospitalization outcomes of bone grafting procedures in a cohort of 5- to 13-year-old patients with a diagnosis of cleft lip and palate. "