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Cinoxacin (Cinobac)
Synthetic antimicrobial related to OXOLINIC ACID and NALIDIXIC ACID and used in URINARY TRACT INFECTIONS.
Also Known As:
Cinobac
; Clinoxacin; Compound 64716; Acid, Azolinic; Azolinic Acid; (1,3)Dioxolo(4,5-g)cinnoline-3-carboxylic acid, 1-ethyl-1,4-dihydro-4-oxo-
Networked:
64
relevant articles (
12
outcomes,
9
trials/studies)
Relationship Network
Drug Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
3-Ring Heterocyclic Compounds
Cinoxacin: 64
bis(cinoxacinate)copper(II)
Heterocyclic Acids
Cinoxacin: 64
bis(cinoxacinate)copper(II)
Experts
1.
Emiliani, F
: 1 article (02/2003)
2.
Quercia, O
: 1 article (02/2003)
3.
Rafanelli, S
: 1 article (02/2003)
4.
Stefanini, G Francesco
: 1 article (02/2003)
Related Diseases
1.
Urinary Tract Infections (Urinary Tract Infection)
06/01/1982 - "
Prophylactic efficacy of cinoxacin in recurrent urinary tract infection: biologic effects on the vaginal and fecal flora.
"
03/01/1976 - "
Efficacy of cinoxacin in urinary tract infections.
"
09/01/1982 - "
Initial studies demonstrate that cinoxacin has substantial efficacy as a prophylactic agent for those women who experience recurrent, symptomatic urinary tract infections.
"
01/01/1982 - "
The results of this study show that cinoxacin is a useful drug for the treatment of urinary tract infection due to susceptible organisms.
"
06/01/1988 - "
Prevention of recurrent urinary tract infections in premenopausal women by post-coital administration of cinoxacin.
"
2.
Reinfection
11/01/1982 - "
The results of this study have shown that cinoxacin was significantly more effective than placebo in preventing urinary tract infection in patients with a history of frequent recurrent infections.
"
01/01/1982 - "
In one patient in the cinoxacin group, the pathogen was not eradicated, and two patients who received nitrofurantoin had a reinfection with a new pathogen.
"
04/01/1987 - "
[Comparative evaluation of cinoxacin, cotrimoxazole and pipemidic acid in recurrent infections of the lower urinary tract in long-term therapy].
"
3.
Infections
11/01/1982 - "
One patient in the cinoxacin group and eight patients in the placebo group developed an infection during the study.
"
11/15/1988 - "
[Treatment of postoperative urinary infections in obstetrics and gynecology with cinoxacin].
"
04/01/1988 - "
Cinoxacin is easily managed, produces no side effects and can be administered orally, all of which makes it a drug of first choice in the treatment of prophylaxis of lower urinary infections.
"
04/01/1988 - "
The results obtained in 15 patients with infections of the lower urinary tract given 500 mg cinoxacin in two daily doses for 10 days are reported.
"
04/01/1988 - "
[Cinoxacin in infections of the lower urinary tract].
"
4.
Pyelonephritis
12/01/1982 - "
The efficacy of cinoxacin in the treatment of pyelonephritis, compared with these proven agents, has been examined in only small numbers of patients, and cinoxacin is more expensive than these agents.
"
10/01/1974 - "
Cinoxacin: effectiveness against experimental pyelonephritis in rats.
"
10/01/1974 - "
The antimicrobial activity of cinoxacin, 1-ethyl-4(1H)-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid, previously reported as compound 64716, was determined and compared with other antimicrobial agents at a dosage of 12 mg/kg once daily in a descending pyelonephritis rat model with Escherichia coli and Proteus mirabilis as infecting organisms.
"
5.
Urologic Diseases (Urinary Tract Disease)
08/01/1980 - "
It is concluded that cinoxacin will be useful in the treatment of urinary tract disease because of the high urinary antibacterial activity produced.
"
Related Drugs and Biologics
1.
Norfloxacin
2.
Oxolinic Acid
3.
Ciprofloxacin (Cipro)
4.
Nitrofurantoin (Macrodantin)
5.
Anti-Bacterial Agents (Antibiotics)
6.
Anti-Infective Agents (Microbicides)
7.
Ofloxacin (Ofloxacine)
8.
Pipemidic Acid (Palin)
9.
Excitatory Amino Acid Antagonists
10.
Dizocilpine Maleate (Dizocilpine)
Related Therapies and Procedures
1.
Therapeutics
2.
Aftercare (After-Treatment)