|3.||Wounds and Injuries (Trauma)
|1.||Hirano, Shigeru: 25 articles (07/2014 - 01/2003)|
|2.||Mustoe, Thomas A: 24 articles (03/2015 - 03/2002)|
|3.||Ferguson, Mark W J: 24 articles (04/2012 - 02/2003)|
|4.||Longaker, Michael T: 23 articles (04/2014 - 01/2002)|
|5.||Li, Ren-Ke: 21 articles (01/2015 - 09/2003)|
|6.||Bax, Jeroen J: 20 articles (10/2014 - 06/2004)|
|7.||Tredget, Edward E: 19 articles (12/2015 - 09/2002)|
|8.||Bayat, Ardeshir: 19 articles (09/2015 - 02/2003)|
|9.||Alster, Tina S: 19 articles (10/2012 - 01/2002)|
|10.||Ogawa, Rei: 18 articles (03/2015 - 03/2003)|
11/01/2009 - "Focusing on quantitation of deposited collagen, the Scar-in-a-Jar was most effective in assessing novel inhibitors that may have multiple targets, such as microRNA29c, found to be a promising antifibrotic agent. "
02/01/2015 - "Moderately resected hearts had 15±2% of the wall infiltrated by a collagen scar; significantly greater scar infiltration (23±4%) was observed in hearts with large resections. "
09/01/2013 - "The collagen implant significantly improved the bioelectrical characteristics, gross appearance and tissue alignment of the healed, treated tendons, compared to the healed, control scars. "
06/07/2011 - "In both repair groups there was a significant reduction in collagen staining between 6 and 12 weeks, suggestive of scar remodelling. "
07/01/2004 - "ECG showed a significant improvement in the quality of scar formation both in terms of maturity and orientation of the collagen fibers. "
06/01/2009 - "The results showed statistically significant correlations for each pair in this clinical scar scale (p<0.01), with the best correlation found between scar cosmetic outcome and scar colour. "
08/01/1998 - "Without producing scars or permanent pigmentary changes a very good cosmetic result has been achieved and stigmatisation and psychic burden of this patient has been relieved."
09/01/1997 - "The Z-plasty is an excellent procedure for both lengthening contracted scars and/or changing the direction of scars for improved cosmetic effect. "
01/01/2015 - "Significantly improved cosmetic outcomes were observed among certain studies using the visual analogue scale (experimental group: median score 8.25 [range 6 to 10]) versus control group: median score 6.38 [range 2 to 9]; P<0.001) and the Stony Brook Scar Evaluation Scale (experimental group score: 6.7 versus control group score: 4.17; P<0.001) assessments. "
10/01/2014 - "On follow-up, the measured MIT scar was significantly shorter (2.22 vs 3.98 cm; P < .00001), which resulted in significantly improved cosmetic satisfaction ratings (9.56 vs 8.66; P = .03). "
01/01/2013 - "In treatment studies, silicone gel sheeting produced a statistically significant reduction in scar thickness (mean difference (MD) -2.00, 95% CI -2.14 to -1.85) and colour amelioration (RR 3.49, 95% CI 1.97 to 6.15) but again these studies were highly susceptible to bias. "
05/01/2002 - "In most cases reconstruction with Skin-Expander and silicone implants meets the patients' desires: low-risk operation, fewer additional scars, and similar and improved breasts on both sides."
05/01/2006 - "All parameters in the Vancouver Scar Scale improved in both groups, although patients treated with the soft silicone dressing showed greater and more rapid improvements compared with the non-treated patients, while their assessments of the condition of the scar were more favourable. "
06/01/1999 - "Both the silicone gel cushion and the silicone gel sheeting treatments were effective in decreasing scar volume, 53.0% and 36.3%, respectively. "
10/01/1993 - "The silicone gel sheets resulted in moderate improvement in scar thickness, scar color and was noted to be effective to some degree in all tested. "
04/01/2013 - "Nerve co-morbidity, scar problems, soft-tissue complications and compartmental syndrome were not problems in the study population despite the type of treatment. "
10/01/2010 - "Using experimental paradigms that enabled functional distinction between the resident and infiltrating cells, our most recent studies further corroborated our repair perception, showing that (a) infiltrating monocyte-derived macrophages are recruited following injury and localize to the margins of the lesion, unlike the activated resident microglia that are not compartmentalized, and (b) activated resident microglia and infiltrating monocyte-derived macrophages perform distinct roles; recruited blood-derived macrophages display an (IL-10-dependent) anti-inflammatory phenotype when they become co-localized with the glial scar. "
03/01/2005 - "The highest (60)Co activity concentrations in this study were detected at Drigg Barn Scar. "
09/01/2015 - "Both COSII markers were converted into co-dominant SCAR markers. "
09/01/2015 - "We developed highly reliable co-dominant SCAR markers linked to the Frl gene. "
12/01/2009 - "The nonablative 1,550-nm erbium-doped fractional photothermolysis system (FPS) has been effectively used for scar treatments, but it seems that several sessions of treatment must be delivered to achieve satisfactory improvement. "
01/01/2000 - "Three patients with erbium resurfacing had scarring present. "
03/01/2008 - "A novel 1,550-nm erbium-doped laser (Fraxel, Reliant Technologies Inc.) has been shown to be effective in the treatment of photodamaged skin and scars with minimal postoperative recovery; however, studies evaluating its side effects and complication rates have been limited. "
03/01/2007 - "A novel treatment using a 1,550-nm erbium-doped fiber laser to induce fractional photothermolysis of treated skin has been used to resurface photodamaged skin but has not been studied previously in patients with atrophic scars to determine its effectiveness for this condition. "
10/01/2001 - "However, recent studies have shown the efficacy of the erbium laser in removing delicate and moderate scars. "
|6.||Mitomycin (Mitomycin-C)FDA LinkGeneric
04/01/2007 - "Mitomycin C (MMC) acts as a potent fibroblastic inhibitor, and topical application of MMC is effective in preventing scar formation. "
12/01/2005 - "In this very limited number of cases, we found that the intraoperative use of mitomycin C appeared to have been helpful in preventing scarring in both congenital and secondary fibrotic atresias of the external auditory canal. "
08/25/2010 - "There is increasing evidence that topical application of mitomycin-C can be beneficial in reducing epidural scar adhesion. "
03/01/2005 - "Use of topical mitomycin C in the ear may be beneficial in reducing scar and granulation tissue formation. "
12/01/2004 - "After the recognition that topical application of Mitomycin-C (MMC) inhibits fibroblast proliferation and is effective in preventing scar formation, many studies have been carried out on this subject outside the scope of urology. "
|7.||Succimer (Dimercaptosuccinic Acid)FDA Link
04/01/1999 - "The English language medical literature was reviewed to determine the strength of the published evidence for the assertion that dimercaptosuccinic acid scintigraphy (DMSA) is superior to ultrasound (US) in the detection of established renal scarring in children. "
07/01/2014 - "The aim of our study was to compare the efficacy of unenhanced magnetic resonance urography (MRU) and Tc-99(m) dimercaptosuccinic acid (Tc-DMSA) scintigraphy to dectect renal scars. "
11/01/2012 - "Dimercaptosuccinic acid imaging is the 'gold standard' for the detection of cortical defects and diagnosis of scarring of the kidneys. "
05/01/2009 - "DMSA scintigraphy was regarded as the gold standard for the diagnosis of renal scarring. "
08/01/2007 - "Accuracy of ultrasonic detection of renal scarring in different centres using DMSA as the gold standard."
|8.||Fluorouracil (Carac)FDA LinkGeneric
03/01/1997 - "A significant reduction (P = 0.0001) in the amount of scarring was noted in eyes treated with 5-FU. "
01/01/2009 - "Intralesional fluorouracil is a safe and effective means of controlling problem scars in terms of both recurrence and symptom control. "
07/01/2015 - "After being treated by ethosomes containing 5-FU (D=60±10 nm), the fibroblast and collagenous fiber distributed sparsely in the deep scar tissue. "
01/01/2014 - "In addition, the value of the Scar Elevation Index (SEI) of 5-FU EGs group in the rabbit ear scar model was lower than that of 5-FU Phosphate Buffered Saline gel and Control groups. "
01/01/2014 - "Monotherapy with 5-FU did not change the scar formation in the back (p = 0.317). "
01/01/2010 - "The new gold standard for myocardial viability assessment is late gadolinium enhancement-cardiovascular magnetic resonance (LGE-CMR); this technique has demonstrated that the transmural extent of scar predicts segmental functional recovery. "
07/01/2015 - "Super-resolution reconstruction of late gadolinium-enhanced MRI for improved myocardial scar assessment."
02/01/2015 - "Late gadolinium enhancement cardiac magnetic resonance (LGE-CMR) imaging is the gold standard for myocardial scar evaluation. "
05/01/2014 - "The addition of first-pass stress perfusion and late gadolinium enhancement (scar) further improved diagnostic confidence (sensitivity 82.4%, specificity 95.8%, positive predictive value 93.3%, negative predictive value 88.5%, and diagnostic accuracy 90.2%). "
01/01/2014 - "Subsequently a clinical protocol was developed, to assess the feasibility of scar tissue detection with native T(1ρ)-mapping in patients (n = 21) with chronic MI, and correlated with gold standard late gadolinium enhancement (LGE) CMR. "
07/01/2015 - "Fractionated carbon dioxide (CO2) can treat hypopigmented scars. "
01/01/2012 - "Endoscopy-assisted cubital tunnel release under carbon dioxide insufflation demonstrated similar results compared with conventional open surgeries, besides, it may avoid problems such as long incision, painful scarring, and have additional advantages of providing an extended endoscopic view, which is safe and mini-invasive with favorable results in a 12-month follow-up."
03/01/2009 - "This brief report will share information about the use and safety of inflating the bladder with carbon dioxide to delineate the margins during laparoscopic dissections near the bladder in patients who have scarring, adhesions, or challenging anatomy. "
08/01/1985 - "Three affected patients have been treated with carbon dioxide "laserbrasion," which has resulted in a long-lasting improvement without scarring or recurrence. "
11/01/2010 - "Ablative 10,600-nm carbon dioxide fractional laser systems (CO₂ FS) have been used successfully for the treatment of various types of scars. "
01/01/2015 - "A number of treatments are available for red residual lesions but thanks to its effect on erythematous and vascular lesions, PDL has been shown to provide the most reproducibly good results and is the laser method of choice for this type of scar. "
05/01/2011 - "Every lesion (10/10) that initially measured <2 mm resolved completely after laser treatment with minimal scarring noted at the treatment site based on histology. "
10/01/2009 - "In our patients, using this sequential laser device achieved an almost complete clearance of the VM with no scarring."
04/01/2006 - "All patients showed complete remission after 1.59 (1-5) laser sessions and no scarring was observed. "
07/01/2001 - "Excellent results, however, can be achieved with this laser, up to 50% or more overall clinical improvement, in patients with milder photodamage and scarring (Glogau classes I and II). "
03/01/1995 - "Non-surgical and surgical procedures have been developed to correct this situation, the Abbe-Wharton-McIndoe operation is one with the best results, but it has the disadvantage that the scar produced in the place where the skin graft is taken has an awful appearance. "
06/01/2001 - "The preliminary results with this protocol in a group of 12 children have shown better quality scars, more harmonious maxillary arches, an excellent occlusion of the deciduous dentition, and preservation of the positive results obtained with the periosteal tibial graft."
01/01/1992 - "The good results of primary wound healing, the absence of horizontal scars and the possibility of mobilisation of epithelium from the cleft region to cover the transplant with mucosa from the alveolar process are the advantages of this procedure."
06/01/2010 - "Thus, the molecular risk score reflects active injury and is superior to either scarring or function in predicting graft failure."
06/01/1998 - "The prelesioned peripheral nerve graft is more effective than the untreated graft in suppressing astrocytic scar formation and in supporting the outgrowth of regenerating axons in the dorsal funiculus of rat spinal cord."
10/01/1997 - "Recently, the pulsed Er:YAG laser has been shown to be a highly effective treatment for several kinds of pitted facial scars. "
08/01/2009 - "Although treatment of one patient with the Q-switched ruby laser therapy failed, the remaining patients responded well and had good to excellent skin texture without hypertrophic scarring. "
10/01/1996 - "We report our experiences with two patients whose traumatic tattoos resolved completely without any scarring after ruby laser therapy. "
01/01/2014 - "The combined PDL/Nd:YAG laser significantly improved the appearance of the scars. "
10/01/2013 - "The fractional Er:YAG laser device significantly improved postsurgical scar lines in each patient without significant adverse effects. "
01/01/2013 - "Fractional CO2 laser treatment has led to marked improvement in scars, and fat transfer, or fat grafting, has also recently proven very useful in regenerative medicine. "
11/01/2007 - "Due to its painless nature, rapid healing, low rate of complications and recurrence, and minimal risk of scarring, CO2 laser is an effective treatment for the management of profuse anogenital condylomas in children. "
12/01/1999 - "Significant immediate and prolonged clinical improvement in skin tone, texture, and appearance of CO2 laser-irradiated scars was seen in all patients. "
03/01/2000 - "The CO2 laser proved to be a very useful instrument for bloodless tissue-protective surgery without conspicuous scar formation."
03/01/2015 - "In this trial involving various types of scars, the efficacy of ablative fractional CO2 laser could not be confirmed. "
01/01/1989 - "A study of skin suture following elliptical excision of tattoos from the upper limb shows that when the dermis is supported by a subcuticular non-absorbable suture for 6 months there is (a) a highly significant and numerically considerable (37.5%) reduction of scar stretching over that following conventional interrupted skin suture and (b) a significant reduction of scar width (15.7%) when compared with the same material used as a subcuticular suture for 3 weeks. "
09/01/2004 - "The use of a deep 6/0 polydioxanon (PDS) suture significantly decreased the incidence of scar widening (p < 0.005).The columellar incision can be used safely in the Arab population regardless of their thick, dark, and oily skin. "
01/01/2003 - "Several advantages were observed: shorter operative time, formation of a protective barrier, simplified incision care, no need for suture removal, and improved scar outcome. "
03/01/2003 - "The purpose of this experimental study was to evaluate the efficacy of five synthetic absorbable suture materials in intestinal anastomoses in rats together with their interference with the normal physiopathological cicatrization process. "
03/01/2011 - "The cutaneous lesions were cured leaving behind scars by secondary suture after times of epluchage, and the fine nodular shadows over lungs disappeared finally. "