|2.||Heart Diseases (Heart Disease)
|4.||Esophageal Neoplasms (Esophageal Cancer)
|5.||Pleural Effusion (Pleural Effusions)
|1.||Itkin, Maxim: 5 articles (07/2013 - 03/2011)|
|2.||Ryu, Jay H: 4 articles (10/2015 - 02/2003)|
|3.||Taveira-DaSilva, Angelo M: 4 articles (01/2015 - 12/2005)|
|4.||Moss, Joel: 4 articles (01/2015 - 12/2005)|
|5.||Sahn, Steven A: 4 articles (01/2008 - 02/2003)|
|6.||Alten, Jeffrey A: 3 articles (07/2015 - 05/2014)|
|7.||Nichols, Francis C: 3 articles (01/2015 - 07/2005)|
|8.||Seyama, Kuniaki: 3 articles (09/2013 - 08/2008)|
|9.||McAnulty, Jonathan F: 3 articles (12/2011 - 09/2005)|
|10.||Date, Hiroshi: 3 articles (09/2010 - 08/2008)|
|1.||Octreotide (Sandostatin)FDA LinkGeneric
06/01/2015 - "We concluded that octreotide is effective in the management of moderate to large volume chylothorax. "
06/01/2015 - "Twelve case reports found octreotide effective in reduction of the volume and arrest of chylothorax. "
06/01/2015 - "Sixteen of 19 papers found octreotide to be effective in the treatment of chylothorax. "
07/01/2006 - "Several case reports and series have shown that octreotide is safe and probably effective in both children and adults with chylothorax of different origins. "
01/01/2010 - "There are cases and case series indicating that octreotide use in chylothorax seems to be safe and effective. "
|2.||Somatostatin (Somatotropin Release-Inhibiting Factor)IBA
04/01/2011 - "Further observations are needed before somatostatin can be recommended as a standard first-line treatment procedure for chylothorax in infants."
03/01/2002 - "Somatostatin seems effective in the management of chylothorax, although its mechanism of action is unclear. "
09/01/2005 - "Somatostatin can be a safe and effective option in the treatment of both primary and secondary neonatal chylothorax refractory to conservative treatment."
01/01/2012 - "This is the first paediatric report of the use of somatostatin analogues to manage chylothorax in Generalised Lymphatic Dysplasia and we conclude that they represent a potentially useful treatment modality. "
01/01/2012 - "Use of somatostatin analogues to treat chylothorax in a child with Generalised Lymphatic Dysplasia."
10/01/1993 - "Application of OK-432, even in such a small dose as 1.5 KE, appeared very useful for the treatment of postoperative chylothorax."
05/01/2012 - "Intrapleural instillation of OK-432 has recently been used to successfully treat neonatal and fetal chylothorax. "
04/01/2012 - "Intrapleural injection of OK-432 as the primary in-utero treatment for fetal chylothorax."
01/01/2012 - "Forty-nine (62.8%) fetuses had a normal karyotype and were recognized to have fetal chylothorax; of these, 45 underwent intrapleural injection of 0.1KE OK-432 per side per treatment. "
05/01/2007 - "Use of OK-432 is a promising therapy for selected fetuses with persistent chylothorax early in the second trimester."
11/01/1999 - "Four spontaneous chylothorax cases were treated by VATS and talc pleurodesis with immediate positive results. "
06/01/2007 - "Talc pleurodesis in the treatment of chylothorax following mitral valve replacement."
12/01/2006 - "Initial conservative treatment failed twice and the chylothorax was successfully treated through sequential bilateral videothoracoscopy with an interval of 6 days between the two interventions and pleurodesis with spray talc."
12/01/2006 - "[Bilateral Chylothorax after delivery: an infrequent case treated with videothoracoscopic talc pleurodesis]."
04/01/2004 - "This case describes a patient with non-Hodgkins Iymphoma who developed recurrent bilateral chylothorax requiring repeated pleural aspirations and eventually talc pleurodesis which failed."
|5.||Sirolimus (Rapamycin)FDA Link
09/01/2013 - "The remaining 7 patients had chylous effusion at the start of sirolimus treatment; the chylothorax resolved completely within 1-5 months of treatment in 6 of these cases. "
06/01/2015 - "We conclude that sirolimus should be considered in the management of pLAM-related chylothorax, perhaps before surgical intervention. "
06/01/2015 - "Discontinuation of sirolimus for abdominal surgery led to recurrence of the chylothorax. "
06/01/2015 - "Commencement of sirolimus 2 mg daily (2 mg alternating days had failed) led to resolution of chylothorax after 20 days. "
10/01/2013 - "Although mammalian target of rapamycin inhibitors were major drugs for lymphoangioleimyomatosis, we believed that the chylothorax was associated with EVL. "
|6.||Fibrin Tissue Adhesive (Fibrin Sealant)IBA
07/01/2003 - "Fibrin glue has been shown to be effective in improving postoperative chylothorax following various thoracic procedures and in reducing lymphorrhea after axillary dissection. "
09/01/1998 - "[Postoperative chylothorax treated with fibrin glue and absorbent mesh: a case report]."
01/01/1998 - "Chylothorax therapy utilizing fibrin glue and liver and kidney biopsy may be performed."
09/01/1994 - "Control of the chylothorax was achieved by a parietal pleurectomy and application of fibrin glue (Tisseel). "
04/01/1994 - "In this report, the authors discuss their recent experience with fibrin glue in the management of a 600-g premature neonate who had a postoperative chylothorax. "
|7.||Ethiodized Oil (Ethiodol)FDA Link
05/01/2004 - "Diagnostic Lipiodol lymphography was required before the chylothorax was cured. "
02/01/2015 - "Thoracic Duct Embolization with Lipiodol for Chylothorax due to Thoracic Endovascular Aortic Repair with Debranching Procedure."
01/01/2015 - "In this article, we describe the successful treatment of a case of intractable chylothorax by lipiodol lymphography. "
01/01/2015 - "Management of Aortic Replacement-Induced Chylothorax by Lipiodol Lymphography."
11/01/2013 - "Lipiodol lymphangiography may be an effective therapeutic method for treating conventionally untreatable chylothorax. "
|8.||Thyroxine (Levothyroxine)FDA LinkGeneric
02/01/2003 - "This study was performed to characterize the clinical course and identify appropriate management options for chylothorax occurring in patients with LAM. "
02/01/2003 - "Chylothorax occurring in patients with LAM has a variable clinical course. "
02/01/2003 - "Eight of 79 patients (10.1%) with LAM had chylothorax. "
02/01/2003 - "Identification and retrospective review of available medical records on patients with LAM and chylothorax. "
02/01/2003 - "Optimal management of chylothorax, a well-recognized complication of LAM, in these patients has not been defined. "
|10.||tranilast (N 5')IBA
10/01/2011 - "Normal dogs (n = 5) and dogs with chylothorax (n = 8). "
03/01/2006 - "Total protein content and cell count were measured in the aspirates, which were compared with chylothorax cases (n = 5) requiring fetal shunt placement. "
01/01/2015 - "Chylothorax could be scintigraphically confirmed in n = 9, chylous ascites in n = 5 scintigraphies, and excluded in n = 10 patients. "
10/01/2011 - "Nine patients experienced postoperative complications: persistent air leak (n = 5, 13.9%), chylothorax requiring surgical intervention (n = 4, 11%), and adult respiratory distress syndrome (n = 1, 3.9%). "
04/01/2009 - "Pedal lymphangiography was performed in 9 patients (6 men and 3 women; mean age, 59 years) who were unlikely to be cured only by conservative treatment - a low-fat medium-chain triglyceride diet, total parenteral nutrition and insertion of a drainage tube - and in whom chylothorax (n = 5), chylous ascites (n = 2) and lymphatic fistulae (n = 2) were refractory to conservative treatment. "
11/01/2010 - "Ligation of cisterna chyli may represent a safe and effective ultimate treatment in children with persistent chylothorax."
06/01/2013 - "In cases of refractory postoperative chylothorax, surgical therapy such as thoracic duct ligation should be considered when discharge from the drainage tube is >30 ml/kg/day or chylothorax is not improved within 10 days."
12/01/2013 - "In this study, we describe the technique of transabdominal mass ligation of the thoracic duct as an elective, simple and safe method for the prevention of postoperative chylothorax. "
01/01/2012 - "We conclude that for patients undergoing oesophagectomy, although there are conflicting results from retrospective studies, prospective randomised controlled trial evidence points to prophylactic ligation of the thoracic duct as an effective measure to reduce the incidence of post-operative chylothorax."
01/01/2012 - "Of the four remaining retrospective studies, one showed an increase in chylothorax rate following ligation whilst three showed a reduction in the incidence of chylothorax (although in only one of these three studies was this decrease statistically significantly). "
12/01/1996 - "Complete and permanent remission of the chylothorax was achieved within only ten days following talcum pleurodesis, alimentary measures and induction of systemic steroid therapy. "
01/01/2012 - "To assess the use and efficacy of in-utero pleurodesis for experimental treatment of bilateral fetal chylothorax. "
02/01/2014 - "In the present study, we investigated the effectiveness of a conservative approach (diet or pleurodesis) to the management of chylothorax. "
10/01/2015 - "One patient (8%) had a chylothorax and 7 (58%) had recurrent pneumothoraces, 4 (33%) of which required pleurodesis. "
10/01/2015 - "Five patients were treated with chemical pleurodesis of persistent chylothorax. "
12/01/2001 - "Thoracoscopy is a safe and effective procedure for the treatment of chylothorax complicating esophagectomy. "
02/01/2015 - "Chylothorax after esophagectomy cured by intranodal lymphangiography: a case report."
05/01/2015 - "There was no significant difference in the incidence of chylothorax following transhiatal, 3/35 = 8.57 % or transthoracic esophagectomy 1/10 = 10 % (p = 0.898). "
05/01/2015 - "Chylothorax is an uncommon complication of esophagectomy. "
05/01/2015 - "Patients with a BMI < 25 are more likely to develop chylothorax after esophagectomy. "
09/01/1994 - "Thoracotomy with parietal pleurectomy on the side of the effusion is usually effective in controlling the chylothorax. "
05/01/2015 - "Chylothorax [6/251 (2.4%)] and RLNI [6/251 (2.4%)] were significantly more common in the RVATS group than in the open thoracotomy and standard VATS groups. "
07/01/2013 - "A case needed re-thoracotomy due to medical treatment failure for chylothorax. "
04/01/2012 - "Early and delayed chylothorax can be managed efficiently by a thoracoscopic approach replicating the sealing techniques used in thoracotomy."
01/01/2011 - "Left chylothorax exacerbated because of the complication of right thoracotomy. "
|5.||Chest Tubes (Chest Tube)
06/01/1999 - "Clinical manifestations at birth, such as respiratory distress, tachypnea and chylothorax were successfully relieved by the insertion of chest tube and medical therapy. "
10/01/2000 - "After several thoracocentesis chylothorax was developed which was cured by permanent chest tube drainage."
05/01/1991 - "On the basis of this experience, we suggest a step-by-step approach: (1) insertion of chest tube after 3 to 4 pleural punctures; (2) 1-week trial of MCT diet, with intravenous support to correct protein losses; (3) TPN if chylothorax increases or persists with large volumes; (4) Doppler echocardiography or phlebography to rule out obstruction of major thoracic veins; and (5) insertion of TPN line in inferior vena cava in case of such obstruction; and (6) direct surgical approach to the thoracic duct after 4 weeks of unsuccessful nonoperative treatment.(ABSTRACT TRUNCATED AT 250 WORDS)"
09/01/2015 - "Persistent chylothorax was successfully resolved in 65 patients (65 of 70; 93%) within 15 days (2-79 days) after the first or second TDML; 5 patients died with a chest-tube(s) in situ. "
01/01/2015 - "All prior cases of tension chylothorax were managed operatively with decompressive chest tube placement followed by open thoracic duct repair. "