Chronic Disease (Chronic Diseases)

Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care. (Dictionary of Health Services Management, 2d ed)
Also Known As:
Chronic Diseases; Chronic Illnesses; Disease, Chronic; Chronic Illness; Chronically Ill; Diseases, Chronic; Illness, Chronic; Illnesses, Chronic
Networked: 9079 relevant articles (342 outcomes, 803 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Anemia
3. Cardiovascular Diseases (Cardiovascular Disease)
4. Infection
5. Rheumatoid Arthritis


1. Ferrucci, Luigi: 29 articles (01/2015 - 02/2003)
2. Bandinelli, Stefania: 19 articles (01/2015 - 01/2006)
3. Guralnik, Jack M: 18 articles (01/2015 - 02/2003)
4. Semba, Richard D: 16 articles (07/2012 - 03/2002)
5. Holick, Michael F: 14 articles (01/2014 - 03/2004)
6. Aggarwal, Bharat B: 13 articles (10/2014 - 01/2007)
7. Kristal, Alan R: 10 articles (05/2014 - 01/2003)
8. Fried, Linda P: 10 articles (06/2012 - 06/2005)
9. Bruera, Eduardo: 9 articles (09/2015 - 02/2004)
10. Weiss, Günter: 9 articles (09/2014 - 06/2002)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Chronic Disease:
1. IronIBA
2. AntioxidantsIBA
3. polyphenolsIBA
4. Biological Markers (Surrogate Marker)IBA
11/01/2007 - "Similarly, many studies have demonstrated a significant protection against chronic diseases from a global healthy lifestyle (HL) pattern which includes not only dietary habits but also physical activity and abstinence from smoking, whereas few data regarding the influence of a HL pattern on circulating biomarkers are available. "
06/01/2011 - "  and  Discussion The issues addressed include: (1) development of collaborative care in the context of oncology (e.g., timing of the intervention, tailoring of the intervention, ethical issues regarding randomization of patients, and changes in medical treatment over the course of the study); (2) use of a website by chronically ill populations (e.g., design and access to the website, development of the website and intervention, ethical issues associated with website development, website usage, and unanticipated costs associated with website development); (3) evaluation of the efficacy of intervention (e.g., patient preferences, proxy raters, changes in medical treatment, and inclusion of biomarkers as endpoints); and (4) analyses and interpretation of the intervention (e.g., confounding factors, dose and active ingredients, and risks and benefits of collaborative care interventions in chronically ill patients). "
01/01/2014 - "Decreased consumption of sugar-sweetened beverages improved selected biomarkers of chronic disease risk among US adults: 1999 to 2010."
05/01/2015 - "The purpose of this study was to examine the association of objectively measured lifestyle light-intensity physical activity (LLPA) and moderate-to-vigorous physical activity (MVPA) with various biological markers and chronic diseases among a nationally representative sample of U.S. "
04/01/2015 - "The aim of our study was to establish whether current reference intervals for immune parameters and chemical biomarkers are valid for older individuals including those with chronic diseases, so-called frail elderly. "
5. Vitamin DFDA LinkGeneric
6. Vitamin EFDA LinkGeneric
7. Carotenoids (Carotene)IBA
8. FlavonoidsIBA
9. Carbon MonoxideIBA
10. VitaminsIBA

Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Palliative Care (Palliative Medicine)
3. Highly Active Antiretroviral Therapy (HAART)
4. Long-Term Care
5. Transplants (Transplant)