Chromomycins
A complex of several closely related glycosidic antibiotics from Streptomyces griseus. The major component, CHROMOMYCIN A3, is used as a fluorescent stain of DNA where it attaches and inhibits RNA synthesis. It is also used as an antineoplastic agent, especially for solid tumors.
Also Known As:
Chromomycin
Networked: 19
relevant articles (1 outcomes,
2 trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Experts
1. | Ménézo, Yves:
1 article
(01/2021)
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2. | Afiyatulov, Shamil Sh:
1 article
(04/2017)
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3. | Dmitrenok, Pavel S:
1 article
(04/2017)
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4. | Ermakova, Svetlana P:
1 article
(04/2017)
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5. | Kalinovskaya, Nataliya L:
1 article
(04/2017)
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6. | Kalinovsky, Anatoly I:
1 article
(04/2017)
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7. | Romanenko, Lyudmila A:
1 article
(04/2017)
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8. | Espindola, Ana Paula D M:
1 article
(09/2011)
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9. | Hu, Youcai:
1 article
(09/2011)
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10. | MacMillan, John B:
1 article
(09/2011)
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Related Diseases
1. | Delayed Hypersensitivity (Hypersensitivity, Type IV)
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2. | Chromoblastomycosis (Chromomycosis)
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3. | Neoplasms (Cancer)
04/01/2017
- " This is the first study reporting the inhibitory effects of chromomycin analogs 1-5 on the colony formation of the investigated cancer cell lines. " 11/01/2006
- " Mithramycin and chromomycins are the most representative members of the family, mithramycin being used as a chemotherapeutic agent for the treatment of several cancer diseases. " 03/01/1996
- " Mithramycin, chromomycin, and olivomycin belong to the aureolic acid family of clinically important anti-tumor agents. " 08/01/1977
- " Combination chemotherapy for solid tumors using 5-fluorouracil, chromomycin-A, and prednisolone." 01/01/1976
- " Transfer RNA nucleotidyl transferase from Ehrlich tumor cells was inhibited by proflavine sulfate and ethidium bromide but not by actinomycin D, chromomycin, rifamycin SV, rifampin, daunomycin, or alpha-amanitin. "
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4. | Carcinoma (Carcinomatosis)
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5. | Triploidy
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Related Drugs and Biologics
Related Therapies and Procedures