Chromogenic Compounds

Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).

Also Known As:

Networked: 120 relevant articles (5 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Gruba, Natalia: 4 articles (10/2022 - 03/2021)
2.	Lesner, Adam: 4 articles (10/2022 - 03/2021)
3.	Stachurski, Lech: 3 articles (09/2022 - 03/2021)
4.	Schönherr, Holger: 2 articles (09/2015 - 07/2014)
5.	Neimane, Dagnija: 2 articles (02/2005 - 08/2002)
6.	Sobel, Burton E: 2 articles (02/2005 - 08/2002)
7.	Aradom, Elsa: 1 article (10/2022)
8.	Chowdary, Pratima: 1 article (10/2022)
9.	Garcia, Cecilia: 1 article (10/2022)
10.	Musarara, Molly: 1 article (10/2022)

Related Diseases

1.	Urinary Tract Infections (Urinary Tract Infection) 12/01/2007 - "Examples of target pathogens include Staphylococcus aureus, Streptococcus agalactiae, Salmonella spp. and Candida spp. The inclusion of multiple chromogenic substrates into culture media facilitates the differentiation of polymicrobial cultures, thus allowing for the development of improved media for diagnosis of urinary tract infections and media for the enhanced discrimination of yeasts. " 05/01/1985 - "The development of a distinctive yellow color after the addition of chromogenic substrate to the Limulus amoebocyte lysate-urine reaction mixture was used to measure greater than or equal to 10(5) gram-negative bacteria per ml. A total of 324 urine specimens were assayed, with 68 gram-negative urinary tract infections identified as defined by quantitative urine colony counts of greater than or equal to 10(5) bacteria per ml. Of these, 68 and 67 of 68 were detected by the chromogenic Limulus amoebocyte lysate assay at urine dilutions of 1:10 and 1:20, respectively. "
2.	Gaucher Disease (Gaucher's Disease) 03/26/1982 - "An improved procedure for diagnosis of Gaucher disease using cultured skin fibroblasts and the chromogenic substrate, 2-hexadecanoylamino-4-nitrophenyl-beta-D-glucopyranoside." 03/26/1982 - "It is therefore the chromogenic substrate of choice for determining a glucocerebrosidase deficiency." 03/14/1980 - "Diagnosis of adult Gaucher disease: use of a new chromogenic substrate, 2-hexadecanoylamino-4-nitrophenyl-beta-D-glucopyranoside, in cultured skin fibroblasts."
3.	Urethritis 03/01/1983 - "Thus, use of a chromogenic substrate greatly improved the utility and speed of the LAL assay for evaluating men with exudative urethritis while not affecting the accuracy of the test." 03/01/1983 - "A chromogenic substrate was used with Limulus amoebocyte lysate (LAL) and compared by parallel testing with the traditional gelation LAL method for the rapid evaluation of exudative urethritis in 125 male patients. " 03/01/1983 - "Rapid evaluation of gonococcal and nongonococcal urethritis in men with Limulus amoebocyte lysate and a chromogenic substrate."
4.	Alcoholic Liver Diseases (Alcoholic Liver Disease) 12/31/1993 - "By means of immunoinhibition by specific salivary monoclonal antibodies in combination with a chromogenic substrate, assays of serum amylase were performed in control subjects, in chronic alcohol misusers in relapse or remission and in patients with alcoholic liver disease (ALD). "
5.	Adenocarcinoma 01/01/1988 - "In 14 patients with adenocarcinoma of the colon or rectum (Duke stages A to D), positive results for neuraminidase were obtained with the isolated leukocytes at pH 6. These were tested by a cytochemical method using a chromogenic substrate for neuraminidase. "

Related Drugs and Biologics

1.	Neuraminidase (Sialidase)
2.	Culture Media
3.	Monoclonal Antibodies
4.	Amylases
5.	Enzymes
6.	Thrombin
7.	Immunosorbents
8.	valyl-leucyl-lysine 4-nitroanilide
9.	Thromboplastin (Tissue Factor)
10.	Protein C

Related Therapies and Procedures

1.	Central Venous Catheters
2.	Therapeutics
3.	Mastectomy (Mammectomy)
4.	Subcutaneous Injections