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Sterol O-Acyltransferase

An enzyme that catalyzes the formation of cholesterol esters by the direct transfer of the fatty acid group from a fatty acyl CoA derivative. This enzyme has been found in the adrenal gland, gonads, liver, intestinal mucosa, and aorta of many mammalian species. EC 2.3.1.26.
Also Known As:
Cholesterol Esterifying Enzyme; Acyl CoA Cholesterol Acyltransferase; Acyltransferase, Acyl-CoA-Cholesterol; Acyltransferase, Cholesterol; Enzyme, Cholesterol Esterifying; Esterifying Enzyme, Cholesterol; O-Acyltransferase, Sterol; Sterol O Acyltransferase; Acyl-CoA-Cholesterol Acyltransferase; Cholesterol Acyltransferase; Acyl-CoA:cholesterol O-acyltransferase
Networked: 152 relevant articles (6 outcomes, 9 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Rudel, Lawrence L: 8 articles (06/2012 - 08/2002)
2. Chang, Ta-Yuan: 7 articles (07/2015 - 01/2002)
3. Aragane, K: 6 articles (09/2001 - 01/2000)
4. Kusunoki, J: 6 articles (09/2001 - 01/2000)
5. Chang, Catherine C Y: 5 articles (07/2015 - 01/2002)
6. Fujinami, K: 5 articles (09/2001 - 01/2000)
7. Kojima, K: 5 articles (09/2001 - 01/2000)
8. Sakashita, Naomi: 4 articles (10/2015 - 11/2003)
9. Tomoda, Hiroshi: 4 articles (12/2011 - 09/2007)
10. Miyazaki, Akira: 4 articles (03/2006 - 09/2003)

Related Diseases

1. Atherosclerosis
2. Hypertriglyceridemia
3. Hypercholesterolemia
4. Hyperlipidemias (Hyperlipidemia)
5. Lecithin Acyltransferase Deficiency (Lecithin:Cholesterol Acyltransferase Deficiency)

Related Drugs and Biologics

1. Lipoproteins (Lipoprotein)
2. Lipase (Acid Lipase)
3. Lipoprotein Lipase (Diacylglycerol Lipase)
4. Acyl Coenzyme A (Acyl CoA)
5. Cholesterol
6. LDL Receptors (LDL Receptor)
7. Phosphatidylcholine-Sterol O-Acyltransferase (Lecithin Cholesterol Acyltransferase)
8. Pre-beta High-Density Lipoproteins
9. Apolipoprotein C-III
10. LDL-Receptor Related Protein 1 (LDL-Receptor Related Protein)

Related Therapies and Procedures

1. Splenectomy
2. Hemoperfusion