Chlorphenamidine (Chlordimeform)

09/01/1980 - "Previous studies demonstrated that the formamidine pesticide chlordimeform (CDM) reversibly inhibited prostaglandin biosynthesis and prevented the late (PG-mediated) phase of carrageenin-induced hind paw edema. "

04/01/2012 - "72 cases of acute severe chlorphenamidine poisoning patients were divided into I and II groups by the principle of a 1:1 sampling according to the order of admission. "
06/01/2003 - "400 patients with severe oral chlorphenamidine poisoning were randomly divided into two groups. "
04/01/1985 - "[Nursing of patients with chlordimeform poisoning]."
05/24/1991 - "[Acute hemorrhagic cystitis following chlordimeform poisoning ]."
04/01/2012 - "Scopolamine has the excellent treatment effect on acute severe chlorphenamidine poisoning patients and protec their hearts, livers, and kidneys. "

01/01/1980 - "Chlordimeform and 2-methyl-4-chloroaniline, a major metabolite of chlordimeform, cause severe hemorrhagic cystitis in humans. "
03/13/1978 - "Bladder biopsy specimens from three affected persons showed severe hemorrhagic cystitis; chlordimeform and 2-methyl-4-chloroaniline, a metabolite of chlordimeform, were present in urine specimens collected three days after exposure. "
05/24/1991 - "[Acute hemorrhagic cystitis following chlordimeform poisoning ]."

01/01/1989 - "The high dosage of chlordimeform and both dosages of lidocaine enhanced the rate of kindling development (mean sessions to stage 5 seizures = 8.6 +/- 1.16, 10.15 +/- 1.04 and 8.5 +/- 0.95, respectively) relative to controls (mean = 14.59 +/- 1.36). "
05/01/1988 - "Electrical kindling of the amygdala and hippocampus was used to evaluate the effects of two formamidines, chlordimeform (CDF) and amitraz (AMZ), upon seizures susceptibility in the rat. "

03/13/1978 - "Nine of 22 workers who packaged the insecticide chlordimeform in a separate shed became severely ill with abdominal pain, dysuria, urgency to void, or hematuria. "