|1.||Bul'bulian, M A: 3 articles (01/2002 - 01/2000)|
|2.||Melnick, R L: 3 articles (06/2001 - 05/2000)|
|3.||Himmelstein, M W: 2 articles (10/2014 - 06/2001)|
|4.||Himmelstein, Matthew W: 2 articles (02/2013 - 05/2004)|
|5.||Buchanich, Jeanine M: 2 articles (03/2007 - 03/2007)|
|6.||Phillips, Margaret L: 2 articles (03/2007 - 03/2007)|
|7.||Marsh, Gary M: 2 articles (03/2007 - 03/2007)|
|8.||Youk, Ada O: 2 articles (03/2007 - 03/2007)|
|9.||Cunningham, Michael: 2 articles (03/2007 - 03/2007)|
|10.||Hall, Thomas A: 2 articles (03/2007 - 03/2007)|
09/01/1989 - "In a previous report by the authors, positive results in both case-control study mouse lung tumor induction short-term test of chloroprene for carcinogenicity was conducted to determine whether chloroprene monomer itself could induce tumor. "
04/01/1999 - "The present study was designed to characterize genetic alterations in the K- and H-ras proto-oncogenes in chloroprene-induced lung and HG neoplasms. "
06/01/1989 - "In the present study a short-term test for the induction of mouse lung tumor by chloroprene was conducted to confirm whether chloroprene monomer itself can induce tumors. "
10/01/2014 - "A constrained maximum likelihood approach to evaluate the impact of dose metric on cancer risk assessment: application to β-chloroprene."
02/01/2013 - "Transcriptional BMD values for the pathway were more similar to differences in tumor response than were estimated target tissue dose surrogates based on the total amount of chloroprene metabolized per unit mass of lung tissue per day. "
|2.||Liver Neoplasms (Liver Cancer)
01/01/1998 - "The study defined a "dose-effect" correlation between exposure to chloroprene and death with liver cancer."
01/01/2002 - "The findings are reliably higher risk of morbidity and mortality with hepatic cancer, dose--effect dependence between chloroprene exposure and occurrence of and mortality with hepatic cancer."
06/01/2001 - "Our results did not confirm the excess of risk of liver cancer discovered during other cohort studies aiming to evaluate the role of chloroprene. "
01/01/2001 - "Increased mortality with liver cancer and lympholeucosis was revealed among workers contacting chloroprene."
01/01/2000 - "A direct "dose-effective" correlation was established between liver cancer risk and length of record for occupational exposure to chloroprene. "
|3.||Chromosome Aberrations (Chromosome Abnormalities)
12/01/1977 - "Likewise, several studies have indicated significant excesses of chromosomal aberrations as well as adverse effects on reproductive function following male exposure to chloroprene. "
03/01/1988 - "and below, chloroprene neither induced a significant increase in chromosomal aberrations (CA), sister chromatid exchanges (SCE) or micronucleated erythrocytes, nor significantly altered the rate of erythropoiesis or of bone marrow cellular proliferation kinetics. "
01/01/1990 - "In one study, we observed unusual dose-response in lymphocyte chromosome aberration frequencies after exposure of mice to low doses of a chemical mixture (benzene, chloroprene, epichlorohydrin, and xylene). "
|4.||Lung Neoplasms (Lung Cancer)
01/01/1978 - "A study was undertaken to determine whether exposure to chloroprene increases the risk of lung cancer. "
04/01/1999 - "K-ras mutations were detected in 80% of chloroprene-induced lung neoplasms (37/46) compared with only 30% in spontaneous lung neoplasms (25/82). "
01/01/1978 - "However, the absence of excess lung cancer mortality in other high exposure occupational groups indicates that chloroprene exposure does not increase the risk of lung cancer."
01/01/1972 - "[Lung cancer morbidity among persons working with chloroprene]."
03/20/2007 - "1,3-Butadiene and chloroprene are multisite carcinogens in B6C3F1 mice with the strongest tumor response being the induction of lung neoplasms in females. "
|5.||Skin Neoplasms (Skin Cancer)
|1.||Vinyl Chloride (Chloroethylene)
|10.||Estradiol Congeners (Synthetic Estrogens)