|1.||Kain, Kevin C: 5 articles (02/2007 - 01/2003)|
|2.||Overbosch, D: 3 articles (09/2002 - 02/2000)|
|3.||Chulay, J D: 3 articles (07/2001 - 11/2000)|
|4.||Lalloo, David G: 2 articles (05/2013 - 02/2007)|
|5.||Schlagenhauf, Patricia: 2 articles (03/2013 - 01/2009)|
|6.||Jick, Susan S: 2 articles (03/2013 - 01/2004)|
|7.||Meier, Christoph R: 2 articles (03/2013 - 01/2004)|
|8.||Dinter, Domagoj: 2 articles (01/2013 - 11/2010)|
|9.||Gajski, Goran: 2 articles (01/2013 - 11/2010)|
|10.||Garaj-Vrhovac, Vera: 2 articles (01/2013 - 11/2010)|
01/01/1988 - "This regimen was the most effective in preventing malaria attacks in the previous 12 months, even though over half those on proguanil alone were taking an inadequate dose. "
08/15/2015 - "Protective efficacy against malaria, compared with daily proguanil, was 61% (95% confidence interval, 3%-84%) for MQAS and 36% (40%-70%) for SPAQ. "
05/01/1997 - "None of the 11 patients treated with proguanil were cured of malaria and their phenotype status did not affect the treatment outcome. "
01/01/1992 - "The study shows the importance of malaria in an endemic area among expatriates despite the observance of chemoprophylactics regimens including proguanil."
01/01/1948 - "Trials of Causal Prophylaxis of Malaria with Paludrine."
|2.||Falciparum Malaria (Plasmodium falciparum Malaria)
05/01/2002 - "Polyclonal Plasmodium falciparum malaria in travelers and selection of antifolate mutations after proguanil prophylaxis."
12/01/1997 - "The antifolate proguanil is commonly used in the prophylaxis and treatment of Plasmodium falciparum malaria. "
05/01/1997 - "Disposition of proguanil in Thai patients with uncomplicated falciparum malaria."
03/01/1988 - "The data were suggestive that proguanil may have some causal prophylactic effect against falciparum malaria. "
03/01/1988 - "Among 85 children taking proguanil for 524 human-weeks, there were 17 cases of falciparum malaria and 11 cases of vivax. "
04/01/1999 - "To study this, 95 subjects with uncomplicated Plasmodium falciparum or Plasmodium vivax infections in Vanuatu received proguanil treatment for 3 days (adult relative dose of 300-500 mg/day) and were followed up for 28 days. "
06/01/1999 - "vivax infections, received proguanil treatment for 3 days in daily doses corresponding to adult doses of 300-500 mg. Capillary blood samples were collected on filter paper for determining both human CYP2C19 mutations by polymerase chain reaction and mutation-specific restriction enzyme digestion and blood concentrations of proguanil and its metabolites by high-performance liquid chromatography. "
06/18/1949 - "Proguanil prophylaxis and inter-current infection."
03/01/1949 - "Development of resistance to chlorguanide (paludrine) during treatment of infections with Plasmodium cynomolgi."
01/15/1949 - "Paludrine in prophylaxis and treatment of malarial infections caused by a West African strain of P. "
03/01/1949 - "The suppressive action of paludrine in benign tertian (vivax) malaria."
05/01/1948 - "The therapeutic effectiveness of large doses of paludrine in acute attacks of sporozoite-induced vivax malaria, Chesson strain."
01/01/1947 - "The suppressive and schizonticidal value of paludrine (100 mg.) in vivax malaria."
01/01/1986 - "In this geographical location, where malaria transmission is now light, a combination of strict personal antimosquito measures plus proguanil 200 mg daily produced effective, safe protection, with only a single case of vivax malaria occurring. "
04/01/1999 - "The results suggest that the parent compound proguanil has significant intrinsic efficacy against falciparum and vivax malaria independent of the metabolite cycloguanil."
08/24/1974 - "After the remission of symptoms and reduction in spleen size while on proguanil therapy four patients with the tropical splenomegaly syndrome defaulted from treatment. "
12/01/1998 - "All patients had splenomegaly greater than 10 cm. They were given proguanil 100 mg/day for a minimum of 6 months. "
03/01/1995 - "Massive splenomegaly responsive to proguanil and with features of hairy cell leukaemia."
08/24/1974 - "Relapses after withdrawal of proguanil treatment in tropical splenomegaly syndrome."
12/01/1970 - "Long-term proguanil therapy in idiopathic tropical splenomegaly."
|6.||Antimalarials (Antimalarial Agents)
|3.||Ambulatory Care (Outpatient Care)
|4.||Drug Therapy (Chemotherapy)