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Chlorambucil (Leukeran)

A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
Also Known As:
Leukeran; 4-(Bis(2-chloroethyl)amino)benzenebutanoic Acid; Amboclorin; CB-1348; Chloraminophene; Chlorbutin; Lympholysin; N,N-Di-(2-chloroethyl)-p-aminophenylbutyric Acid; NSC-3088; CB 1348; CB1348; NSC 3088; NSC3088; Benzenebutanoic acid, 4-(bis(2-chloroethyl)amino)-
Networked: 1430 relevant articles (167 outcomes, 214 trials/studies)

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Drug Context: Research Results

Experts

1. Robak, Tadeusz: 17 articles (01/2022 - 03/2002)
2. Tedeschi, Alessandra: 12 articles (01/2022 - 12/2015)
3. Kipps, Thomas J: 10 articles (01/2022 - 04/2015)
4. Bairey, Osnat: 9 articles (01/2022 - 12/2015)
5. Hillmen, Peter: 9 articles (01/2022 - 12/2007)
6. Moreno, Carol: 9 articles (01/2022 - 01/2018)
7. Flinn, Ian W: 8 articles (01/2022 - 05/2006)
8. Ghia, Paolo: 8 articles (01/2022 - 12/2015)
9. Singh, N D Pradeep: 8 articles (07/2020 - 06/2013)
10. Laurenti, Luca: 7 articles (12/2022 - 01/2013)

Related Diseases

1. B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia)
2. Nephrotic Syndrome (Syndrome, Nephrotic)
3. Neoplasms (Cancer)
4. Membranous Glomerulonephritis (Membranous Nephropathy)
5. Lymphoma (Lymphomas)

Related Drugs and Biologics

1. Cyclophosphamide (Cytoxan)
2. Prednisone (Sone)
3. Steroids
4. Rituximab (Mabthera)
5. Prednisolone (Predate)
6. Methylprednisolone
7. fludarabine
8. obinutuzumab
9. Alkylating Agents
10. Vincristine (Oncovin)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Combination Drug Therapy (Combination Chemotherapy)
4. Radiotherapy
5. Aftercare (After-Treatment)