Chilblains (Chilblain)

02/01/1989 - "At a dose of 20 mg to 60 mg daily, nifedipine significantly reduced the time to clearance of existing lesions and prevented the development of new chilblains. "
02/01/1989 - "A pilot study, a double-blind placebo-controlled randomised study and a long term open trial have indicated that nifedipine is effective in the treatment of perniosis. "
01/01/2016 - "In our study, nifedipine was not superior to placebo for treating chronic chilblains. "
02/01/1989 - "The treatment of chilblains with nifedipine: the results of a pilot study, a double-blind placebo-controlled randomized study and a long-term open trial."
01/01/2016 - "A total of 32 patients with chronic chilblains were randomly assigned to nifedipine (30 mg controlled release twice a day) or placebo. "

03/01/2001 - "In two patients, the index lesion was lupus pernio, which significantly improved with infliximab. "
08/01/2015 - "Refractory highly disfiguring lupus pernio: a dramatic and prolonged response to infliximab."
11/01/2008 - "Short course of infliximab for disfiguring lupus pernio."
03/01/2012 - "He was diagnosed of chilblain lupus induced by infliximab, this agent was withdrawn and initiated treatment for chilblains with improvement of lesions. "
01/01/2004 - "Infliximab therapy for sarcoidosis (lupus pernio)."

07/01/2002 - "Lupus pernio is a skin manifestation of sarcoidosis that does not remit spontaneously, and was used as a marker of efficacy of thalidomide for sarcoidosis. "
10/01/2006 - "The efficacy of thalidomide treatment in sarcoidosis with lupus pernio is thought to be due to inhibition of tumour necrosis factor (TNF)-alpha. "

03/01/2005 - "Acupuncture plus massage is superior to dong chuang plaster in therapeutic effect on chilblains."
03/01/2005 - "To compare therapeutic effects of acupuncture plus massage and medicine on chilblains. "

01/01/2022 - "We report the good results obtained in 12 patients with chilblain lesions and the use of oral cinnarizine, a piperazine derivative with many pharmacological properties among whom antihistaminic and calcium channel blocking activities."

10/01/2006 - "The efficacy of thalidomide treatment in sarcoidosis with lupus pernio is thought to be due to inhibition of tumour necrosis factor (TNF)-alpha. "

10/01/2013 - "We present a case of lupus pernio which showed rapid improvement with topical steroids and has yet not developed any systemic involvement even after 6 years of regular follow up. "

10/01/2010 - "To determine outcomes of patients with perniosis treated with hydroxychloroquine. "
10/01/2010 - "Successful treatment of perniosis with hydroxychloroquine."
10/01/2010 - "Hydroxychloroquine is a relatively safe, well tolerated alternative therapy for the treatment of perniosis and should be considered as part of the initial management. "
10/01/2010 - "In this retrospective study, patients with a diagnosis of perniosis treated with hydroxychloroquine were analyzed for dosage required, subjective improvement in signs and symptoms, and adverse drug reactions. "

12/01/2008 - "Pentoxyfylline was shown to be an effective and safe drug for treatment of perniosis, and superior to oral plus topical glucocorticoids p<0.05."

05/01/2003 - "To compare the efficacy of diltiazem with that of nifedipine, and to determine the efficacy of nifedipine in lower doses, 36 chilblains cases were studied. "
05/01/2003 - "Diltiazem vs. nifedipine in chilblains: a clinical trial."

10/01/2010 - "The current medical therapies for perniosis are diverse. "
08/01/2008 - "SLE therapeutics have good effects on SLE-typical symptoms but not on chilblains themselves. "
07/08/1999 - "2: Spring perniosis, therapy and prevention]."
03/01/1968 - "[Association of ionizing radiations and ultrasonics in the therapy of chilblains]."
04/02/1954 - "[Internal therapy of chronic eczemas and of chilblains]."

02/01/2014 - "Improvement in lupus pernio with the successive use of pulsed dye laser and nonablative fractional resurfacing."
01/01/1999 - "We describe a patient with lupus pernio affecting her nose, which showed a dramatic improvement following treatment with the pulse dye laser (PDL). "
01/01/1999 - "The successful treatment of lupus pernio with the flashlamp pulsed dye laser."
01/01/1992 - "We describe a case of nasal lupus pernio successfully managed with the flashlamp pulsed dye laser."
01/01/1992 - "Treatment of lupus pernio with the flashlamp pulsed dye laser."

03/01/2005 - "[Clinical observation on 136 cases of chilblains treated by acupuncture combined with massage]."
03/01/2005 - "Acupuncture plus massage is superior to dong chuang plaster in therapeutic effect on chilblains."
03/01/2005 - "To compare therapeutic effects of acupuncture plus massage and medicine on chilblains. "

02/01/2009 - "We have conducted a study to assess the effect of oral administration of 2000 IU vitamin D3 per day on patients suffering from chronic chilblains. "
02/01/2009 - "Oral administration of 2000 IU vitamin D3 per day is not better than placebo in the treatment of patients with chronic chilblains."

06/01/2014 - "Laser-speckle contrast imaging: a novel method for assessment of cutaneous blood flow in perniosis."
01/01/2006 - "Laser remodelling of nodular nasal lupus pernio."
01/01/2005 - "Effective laser treatment in a case of lupus pernio."