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Chagas Cardiomyopathy

A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
Also Known As:
Chagas' Cardiomyopathy; Cardiomyopathy, Chagas'; Cardiovascular Trypanosomiasis; Cardiomyopathy, Chagas; Myocarditis, Chagas; Trypanosomiasis, Cardiovascular
Networked: 245 relevant articles (12 outcomes, 41 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Heart Failure
2. Trypanosomiasis
3. Chagas Disease (American Trypanosomiasis)
4. Disease Progression
5. Heart Diseases (Heart Disease)

Experts

1. Morillo, Carlos A: 13 articles (08/2021 - 06/2006)
2. Rassi, Anis: 8 articles (06/2022 - 07/2008)
3. Mady, Charles: 8 articles (05/2015 - 01/2006)
4. Schmidt, André: 7 articles (06/2022 - 05/2015)
5. Echeverría, Luis E: 7 articles (02/2022 - 01/2017)
6. Schimke, Ingolf: 7 articles (01/2016 - 02/2010)
7. Wallukat, Gerd: 7 articles (01/2016 - 02/2010)
8. Cunha-Neto, Edecio: 7 articles (05/2015 - 08/2005)
9. Bestetti, Reinaldo B: 7 articles (01/2014 - 11/2004)
10. Rojas, Lyda Z: 6 articles (02/2022 - 01/2017)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Chagas Cardiomyopathy:
1. benzonidazole (benznidazole)IBA
2. Granulocyte Colony-Stimulating Factor (G-CSF)IBA
3. IvabradineIBA
4. HLA Antigens (Human Leukocyte Antigens)IBA
5. Biomarkers (Surrogate Marker)IBA
6. Amiodarone (Amiodarona)FDA LinkGeneric
7. Carvedilol (Coreg)FDA LinkGeneric
8. AutoantibodiesIBA
9. Matrix Metalloproteinases (MMPs)IBA
10. Digoxin (Digitek)FDA LinkGeneric

Therapies and Procedures

1. Therapeutics
2. Heart Transplantation (Grafting, Heart)
3. Cardiac Resynchronization Therapy
4. Drug Therapy (Chemotherapy)
5. Implantable Defibrillators (Implantable Cardioverter-Defibrillator)