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Cerebroside-Sulfatase (Arylsulfatase A)

An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8.
Also Known As:
Arylsulfatase A; Cerebroside Sulfatase; Sulfatase, Sulfatidate; Sulfatidate Sulfatase; Cerebroside-3-sulfate 3-sulfohydrolase
Networked: 324 relevant articles (7 outcomes, 15 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Gieselmann, Volkmar: 27 articles (09/2015 - 01/2003)
2. Gieselmann, V: 14 articles (02/2010 - 03/2000)
3. Matzner, Ulrich: 11 articles (09/2015 - 01/2005)
4. Eckhardt, Matthias: 8 articles (09/2015 - 06/2006)
5. Fogh, Jens: 7 articles (06/2012 - 05/2005)
6. Lüllmann-Rauch, R: 7 articles (01/2006 - 05/2001)
7. D'Hooge, Rudi: 6 articles (07/2015 - 09/2007)
8. Lüllmann-Rauch, Renate: 6 articles (09/2011 - 05/2005)
9. Matzner, U: 6 articles (01/2006 - 05/2000)
10. Stroobants, Stijn: 5 articles (07/2015 - 06/2008)

Related Diseases

1. Metachromatic Leukodystrophy (Sulfatide Lipidosis)
2. Neoplasms (Cancer)
3. Nervous System Diseases (Neurological Disorders)
4. Mucopolysaccharidosis VI (Syndrome, Maroteaux-Lamy)
5. Memory Disorders (Memory Loss)

Related Drugs and Biologics

1. Sulfoglycosphingolipids (Sulfatides)
2. Enzymes
3. Lysergic Acid Diethylamide (LSD)
4. DEAE-Cellulose
5. Complementary DNA (cDNA)
6. N-Acetylgalactosamine-4-Sulfatase (Arylsulfatase B)
7. Arylsulfatases
8. beta-Galactosidase (Lactaid)
9. Molecular Chaperones (Chaperone, Molecular)
10. Interleukin-8 (Interleukin 8)

Related Therapies and Procedures

1. Enzyme Replacement Therapy
2. Transplants (Transplant)
3. Tissue Therapy (Cell Therapy)
4. Intravenous Injections
5. Denervation