Cerebral Arterial Diseases

Pathological conditions of intracranial ARTERIES supplying the CEREBRUM. These diseases often are due to abnormalities or pathological processes in the ANTERIOR CEREBRAL ARTERY; MIDDLE CEREBRAL ARTERY; and POSTERIOR CEREBRAL ARTERY.

Also Known As:

Arterial Diseases, Cerebral; Arterial Disease, Cerebral; Artery Disease, Cerebral; Artery Diseases, Cerebral; Cerebral Arterial Disease; Cerebral Artery Disease; Disease, Cerebral Arterial; Disease, Cerebral Artery; Diseases, Cerebral Arterial; Diseases, Cerebral Artery; Cerebral Artery Diseases

Networked: 27 relevant articles (0 outcomes, 4 trials/studies)

Disease Context: Research Results

Related Diseases

1.	Stroke (Strokes)
2.	Neoplasms (Cancer)
3.	Hypercapnia
4.	Brain Ischemia (Cerebral Ischemia)
5.	Thrombosis (Thrombus)

Experts

1.	Yamauchi, Hiroshi: 2 articles (01/2019 - 01/2015)
2.	Hoshino, Takao: 1 article (07/2022)
3.	Ishizuka, Kentaro: 1 article (07/2022)
4.	Kitagawa, Kazuo: 1 article (07/2022)
5.	Seki, Misa: 1 article (07/2022)
6.	Toi, Sono: 1 article (07/2022)
7.	Kim, Jong S: 1 article (05/2021)
8.	Chen, Hui-Ya: 1 article (12/2019)
9.	Chiang, Shang-Lin: 1 article (12/2019)
10.	Chiu, Ya-Lan: 1 article (12/2019)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Cerebral Arterial Diseases:

1.	Janus Kinase 2IBA 12/01/2023 - "The aim of the present study was to clarify the association between the Janus kinase 2 (JAK2) V617F mutation and large cerebral artery disease (LCAD) in patients with myeloproliferative neoplasms (MPNs). "
2.	Vasodilator Agents (Vasodilators)IBA 07/02/2012 - "The study aims to investigate the effect of cerebral ischemia or hypoperfusion in the evaluation of neural activity with blood-oxygen-level dependent (BOLD) functional magnetic resonance imaging (fMRI), and to examine whether the severity of the compromised hemodynamic status in patients with major cerebral artery diseases could, conversely, be assessed with the use of neural activity as endogenous vasodilator. "
3.	LipidsIBA 05/01/2021 - "However, it should be kept in mind that the role of blood lipids as a risk factor and benefit of lipid-lowering therapy are different among patients with different levels of cerebral arterial diseases. " 05/01/2021 - "More studies are needed to elucidate the appropriate lipid-modifying strategies in patients with stroke with different levels of cerebral artery disease." 05/01/2021 - "Role of Blood Lipid Levels and Lipid-Lowering Therapy in Stroke Patients with Different Levels of Cerebral Artery Diseases: Reconsidering Recent Stroke Guidelines."
4.	Acetazolamide (Diamox)FDA LinkGeneric 11/01/1996 - "The aim of this study was to compare the effect of vasodilative stimuli for the measurement of cerebrovascular reactivity obtained by acetazolamide and hypercapnia in patients with chronic occlusive major cerebral artery disease. "
5.	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 12/01/2002 - "Patients with PAD should be considered to have significant coronary and cerebral arterial disease that requires aggressive risk factor management, including the prescription of antiplatelet drugs, to lower the subsequent risk of myocardial infarction, stroke, and death. " 01/01/2014 - "In conclusion, hinokitiol, an antagonist of collagen GP VI may represent a novel antiplatelet drug for the prevention of thrombi associated with coronary and cerebral artery diseases."
6.	HMGB1 Protein (HMG1)IBA 12/10/2015 - "In this review, we highlight the role of extracellular HMGB1 as a proinflammatory mediator as well as a DAMP in coronary artery disease, cerebral artery disease, peripheral artery disease, and PH. A key focus for future researches on HMGB1 location, structure, modification, and signaling will reveal HMGB1's multiple functions and discover a targeted therapy that can eliminate HMGB1-mediated inflammation without interfering with adaptive immune responses."
7.	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 12/01/2002 - "These pleiotropic properties of statins affect important molecules in vascular biology and help preserve endothelial function in acute and chronic inflammatory states of the cardiovascular system, including coronary and cerebral artery diseases, diabetes, and atherosclerosis. "
8.	Antiphospholipid AntibodiesIBA 10/01/1994 - "The antiphospholipid antibody syndrome may have been responsible for the occlusion of the middle cerebral artery, in this patient and we think that testing for serum antiphospholipid antibodies is important in occlusive cerebral artery disease, especially in moyamoya disease or when moyamoya-like vessels are present."
9.	SodiumIBA 03/01/1995 - "Moreover, a high sodium diet accelerated cerebral arterial disease even when no increases in BP could be detected. "
10.	PapaverineIBA 04/01/1986 - "The patient had taken papaverine for 6 yr for cerebral arterial disease. "

Therapies and Procedures

1.	Therapeutics 01/01/2015 - "Evidence for Cerebral Hemodynamic Measurement-based Therapy in Symptomatic Major Cerebral Artery Disease." 05/01/2021 - "However, it should be kept in mind that the role of blood lipids as a risk factor and benefit of lipid-lowering therapy are different among patients with different levels of cerebral arterial diseases. " 05/01/2021 - "Role of Blood Lipid Levels and Lipid-Lowering Therapy in Stroke Patients with Different Levels of Cerebral Artery Diseases: Reconsidering Recent Stroke Guidelines." 01/01/2015 - "Hypertension is a major risk factor for stroke, and antihypertensive therapy provides general benefit to patients with symptomatic atherosclerotic major cerebral artery disease. " 12/10/2015 - "In this review, we highlight the role of extracellular HMGB1 as a proinflammatory mediator as well as a DAMP in coronary artery disease, cerebral artery disease, peripheral artery disease, and PH. A key focus for future researches on HMGB1 location, structure, modification, and signaling will reveal HMGB1's multiple functions and discover a targeted therapy that can eliminate HMGB1-mediated inflammation without interfering with adaptive immune responses."
2.	Cerebral Revascularization 01/01/2016 - "Superficial temporal artery-middle cerebral artery (STA-MCA) bypass [1,2] is an important and effective type of surgical revascularization that is widely used in the treatment of ischemic cerebral artery disease. " 04/01/2015 - "Extracranial-to-intracranial (EC-IC) arterial bypass is a technically demanding procedure used to treat complex cerebral artery diseases. " 12/01/1985 - "Two hypertensive children with renovascular disease, neurological symptoms, and severe cerebral arterial disease were treated by extracranial-intracranial arterial bypass surgery with improvement of symptoms and easier control of blood pressure. "
3.	Hemofiltration 11/30/1984 - "[Hemofiltration in peripheral and cerebral arterial diseases]."
4.	Contraception (Birth Control) 08/03/1970 - "Jacobs, attending neurosurgeon at the Hackensack Hospital in New Jersey, reported an association between cerebral arterial disease and oral contraception in 3 women at the American College of Angiology meeting in New York City. "
5.	Cardiopulmonary Bypass (Heart-Lung Bypass) 05/01/1991 - "The causes of the cerebral infarction were considered to be the embolism of atheromatous debris from the ascending aorta (3 cases), the cerebral hypoperfusion due to cerebral arterial disease and hypotension during cardiopulmonary bypass (1 cases), and the embolism of the left atrial thrombus formed during repeated supraventricular tachyarrhythmias (1 case). "