Intracranial Arteriosclerosis (Cerebral Atherosclerosis)

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242 relevant articles (5 outcomes, 27 trials/studies) found for this Disease

Description: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA, (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.

Also Known As:

Cerebral Atherosclerosis; Cerebral Arteriosclerosis; Intracranial Atherosclerosis; Arterioscleroses, Cerebral; Arterioscleroses, Intracranial; Arteriosclerosis, Cerebral; Arteriosclerosis, Intracranial; Atheroscleroses, Cerebral; Atheroscleroses, Intracranial; Atherosclerosis, Cerebral; Atherosclerosis, Intracranial; Cerebral Arterioscleroses; Cerebral Atheroscleroses; Intracranial Arterioscleroses; Intracranial Atheroscleroses

Relationship Network

Disease Context: Research Results

Nervous System Diseases: 3406

Central Nervous System Diseases: 929

Brain Diseases: 1117

Cerebrovascular Disorders: 530

Intracranial Arterial Diseases: 5

Intracranial Arteriosclerosis: 242

Vascular Dementia: 891

Cardiovascular Diseases: 18449

Vascular Diseases: 7172

Arterial Occlusive Diseases: 1077

Arteriosclerosis: 2754

Intracranial Arteriosclerosis: 242

Vascular Dementia: 891

Cerebrovascular Disorders: 530

Intracranial Arterial Diseases: 5

Intracranial Arteriosclerosis: 242

Vascular Dementia: 891

Related Diseases

1.	Syndrome
2.	Intermittent Claudication
3.	Stroke (Strokes)
4.	Pathologic Constriction (Stenosis)
5.	Hypertension (High Blood Pressure)
66 Diseases and 84 more articles analyzed in the Research Interface, order at left...

Experts

1.	Higashida, Randall T: 4 articles (06/2006 - 01/2004)
2.	Meyers, Philip M: 3 articles (06/2006 - 01/2004)
3.	Barr, John D: 2 articles (10/2005 - 10/2005)
4.	Society of Interventional Radiology: 2 articles (10/2005 - 10/2005)
5.	American Society of Interventional and Therapeutic Neuroradiology: 2 articles (10/2005 - 10/2005)
6.	Duckwiler, Gary R: 2 articles (10/2005 - 10/2005)
7.	American Society of Neuroradiology: 2 articles (10/2005 - 10/2005)
8.	Wojak, Joan C: 2 articles (10/2005 - 10/2005)
9.	Sacks, David: 2 articles (10/2005 - 10/2005)
10.	Tian, J: 2 articles (05/2004 - 02/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Intracranial Arteriosclerosis:

1.	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 05/01/1999 - "The use of aspirin in these patients cannot be based on direct evidence, but only on analogy with coronary and cerebral atherosclerosis, where it has documented efficacy" 06/01/2008 - "Based on the results of the Warfarin-Aspirin Symptomatic Intracranial Disease study, the risk of ipsilateral stroke at 1.8 years is between 13 and 14% in patients with symptomatic intracranial atherosclerosis" 11/01/2006 - "Based on the results of the Warfarin-Aspirin Symptomatic Intracranial Disease study, the risk of ipsilateral stroke at 1.8 years is between 13 and 14% in patients with symptomatic intracranial atherosclerosis" 01/01/2005 - "For those patients with symptomatic intracranial atherosclerosis, the prognosis is poor; and the recent Warfarin-Aspirin Symptomatic Intracranial Stenosis (WASID) trial results have demonstrated the high risk of warfarin without clear benefit" 01/01/2004 - "The recently NIH-funded Warfarin-Aspirin Symptomatic Intracranial Disease (WASID) trial will compare warfarin with aspirin for stroke prevention in patients with intracranial atherosclerosis" Get all the results and reference details, order at left...
2.	EndostatinsIBA 01/01/2005 - "CONCLUSIONS: A predominance of the inhibitor endostatin within the endogenous angiogenic response is associated with a greater extent and risk of recurrence of symptomatic intracranial atherosclerosis, suggesting that angiogenesis may be beneficial in this condition." 01/01/2005 - "Angiogenesis in symptomatic intracranial atherosclerosis: predominance of the inhibitor endostatin is related to a greater extent and risk of recurrence." 01/01/2005 - "We aimed to investigate the relationship between the pro-angiogenic vascular endothelial growth factor (VEGF) and the anti-angiogenic endostatin, and the extent and risk of recurrence of symptomatic intracranial atherosclerosis" 01/01/2005 - "Diabetes mellitus (OR, 6.04; CI, 1.1 to 32.2; P=0.03) and a higher endostatin/VEGF ratio (OR, 15.7; CI, 2.2 to 112.3; P=0.006) were independently associated with a greater extent of intracranial atherosclerosis" 01/01/2005 - "Studies performed by our group in patients with symptomatic intracranial large-artery atherosclerosis have shown that: (1) C-reactive protein predicts its progression and recurrence, suggesting that inflammation may play a deleterious role in this condition; (2) a high level of the anti-angiogenic endostatin is also associated with a progressive and recurrent intracranial atherosclerosis, which might support a beneficial role for angiogenesis in this group of patients; and (3) elevated lipoprotein(a) concentration and diabetes mellitus characterize those patients with a higher number of intracranial stenoses." Get all the results and reference details, order at left...
3.	PapaverineIBA 06/01/1970 - "Management of chronic brain syndrome secondary to cerebral arteriosclerosis, with special reference to papaverine hydrochloride." 11/01/1978 - "A preliminary analysis of the effect of long-term therapy with oral papaverine has been made in 11 patients with chronic cerebral ischemia due to cerebral arteriosclerosis" Get all the results and reference details, order at left...
4.	Taurine FDA Link 10/01/1999 - "The first publications regarding clinical use of taurine were Italian reports claiming therapeutic efficacy in angina, intermittent claudication and symptomatic cerebral arteriosclerosis" Get all the results and reference details, order at left...
5.	Warfarin (Coumadin)FDA LinkGeneric 06/01/2008 - "Based on the results of the Warfarin-Aspirin Symptomatic Intracranial Disease study, the risk of ipsilateral stroke at 1.8 years is between 13 and 14% in patients with symptomatic intracranial atherosclerosis" 11/01/2006 - "Based on the results of the Warfarin-Aspirin Symptomatic Intracranial Disease study, the risk of ipsilateral stroke at 1.8 years is between 13 and 14% in patients with symptomatic intracranial atherosclerosis" 01/01/2005 - "For those patients with symptomatic intracranial atherosclerosis, the prognosis is poor; and the recent Warfarin-Aspirin Symptomatic Intracranial Stenosis (WASID) trial results have demonstrated the high risk of warfarin without clear benefit" 01/01/2004 - "The recently NIH-funded Warfarin-Aspirin Symptomatic Intracranial Disease (WASID) trial will compare warfarin with aspirin for stroke prevention in patients with intracranial atherosclerosis" Get all the results and reference details, order at left...
6.	glucuronyl glucosamine glycan sulfate (Vessel)IBA 04/01/2006 - "Although several small studies have attempted to address this issue, a comprehensive review regarding the natural history of intracranial atherosclerosis in a vessel-specific manner is lacking" 04/01/2006 - "To this end, we critically review the literature investigating medical management of patients with intracranial atherosclerosis, segregating our findings by vessel" 04/01/2003 - "These differences may play a role in the responses to MV-SMC in the evolution of CAA and other microangiopathies (cerebral arteriosclerosis/lipohyalinosis) and provide insight into mechanisms of degeneration of these cells within vessel walls." 02/01/1979 - "Thus, many potential variables including ocular disease, vessel wall properties, intracranial atherosclerosis and collateral flow may affect the results" 05/01/1969 - "Pattern of vessel involvement in cerebral atherosclerosis" Get all the results and reference details, order at left...
7.	CholesterolIBA 09/02/1963 - "ELECTRON MICROSCOPIC STUDIES ON CHOLESTEROL-INDUCED CEREBRAL ATHEROSCLEROSIS IN COCKERELS." 05/01/2001 - "No significant correlation was seen between severity of cerebral atherosclerosis and age, systolic blood pressure (BP), serum total cholesterol, or triglyceride concentration" 09/01/1991 - "The development and initial lesion sites of cerebral atherosclerosis were studied in hypertensive rabbits fed 0.5 g/day cholesterol in their diet" 01/01/1981 - "Mortality in men 40 to 59 years old from coronary and cerebral arteriosclerosis with varying cholesterol and triglyceride levels in the blood]" 05/01/1980 - "The serum cholesterol level correlated better with the severity of aortic than cerebral atherosclerosis." Get all the results and reference details, order at left...
8.	Retinaldehyde (Retinal)IBA 07/01/1963 - "PATHOPHYSIOLOGICAL STUDY OF RETINAL CIRCULATION AND DIAGNOSIS OF RETINAL BLOOD VESSEL FUNCTION IN HYPERTENSION AND CEREBRAL ARTERIOSCLEROSIS" 07/01/1963 - "PATHOPHYSIOLOGICAL STUDY OF RETINAL CIRCULATION AND DIAGNOSIS OF RETINAL BLOOD VESSEL FUNCTION IN HYPERTENSION AND CEREBRAL ARTERIOSCLEROSIS" 03/15/1979 - "Vincamine in cerebral arteriosclerosis: therapeutic effects evaluated clinically and by retinal fluoro-angiography]" Get all the results and reference details, order at left...
9.	Apolipoproteins E (ApoE)IBA 08/01/2008 - "The APOE epsilon4+ genotype did not predict the risk of IS but was associated with severity of subclinical intracranial atherosclerosis in men on the autopsy study" 05/01/1995 - "The aim of this study was to investigate the degree of coronary and cerebral atherosclerosis in a neuropathologically verified series of AD patients with different apoE genotypes" 08/01/2008 - "The APOE epsilon4+ genotype did not associate with IS, but was related to more severe intracranial atherosclerosis score in men (5.4 vs 4.6, P=0.044)" 08/01/2008 - "We investigated a possible link between IS or the severity of intracranial atherosclerosis and the APOE promoter polymorphisms -219G/T and +113G/C, involved in regulating APOE transcription" Get all the results and reference details, order at left...
10.	Aminophylline (Carine)FDA LinkGeneric 01/01/1960 - "Studies on the effect of euphyllin on cranial rheogram in patients with cerebral atherosclerosis" 11/01/1968 - "A clinico-physiologic analysis of the effects of euphyllin and magnesium collars on patients with incipient cerebral atherosclerosis and a study of the role of these factors in complex sanatorium-climatic therapy]" Get all the results and reference details, order at left...
176 Drugs and Important Bio-Agents and 213 more articles analyzed in the Research Interface, order at left...

Therapies and Procedures

1.	Angioplasty (Angioplasties) 10/01/2005 - "Intracranial angioplasty & stenting for cerebral atherosclerosis: a position statement of the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, and the American Society of Neuroradiology." 10/01/2005 - "Intracranial angioplasty & stenting for cerebral atherosclerosis: a position statement of the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, and the American Society of Neuroradiology." 12/23/2003 - "Angioplasty for intracranial atherosclerosis: is the treatment worse than the disease?" 08/01/2002 - "Stent-assisted angioplasty for intracranial atherosclerosis in the elective patient has proven effective, with an acceptable low rate of morbidity and mortality." 09/01/2008 - "BACKGROUND AND PURPOSE: We sought to compare the clinical outcomes between primary angioplasty and stent placement for symptomatic intracranial atherosclerosis" Get all the results and reference details, order at left...
2.	Stents 01/01/2005 - "Advances in stent design, endovascular wires, and catheters and balloons are allowing endovascular surgeons to safely treat intracranial atherosclerosis" 08/01/2002 - "Stent-assisted angioplasty for intracranial atherosclerosis in the elective patient has proven effective, with an acceptable low rate of morbidity and mortality." 09/01/2008 - "BACKGROUND AND PURPOSE: We sought to compare the clinical outcomes between primary angioplasty and stent placement for symptomatic intracranial atherosclerosis" 10/01/2007 - "Four patients underwent angioplasty and stenting of medically refractory symptomatic intracranial atherosclerosis with the new Wingspan stent system" 01/01/2004 - "Intracranial angioplasty and stent placement for cerebral atherosclerosis." Get all the results and reference details, order at left...
3.	Baths 05/01/1973 - "Changes in the functional state of the nervous and cardiovascular systems in cerebral arteriosclerosis under the effect of baths in an open therapeutic swimming pool]" 09/01/1983 - "Effect of carbon dioxide baths on the hemodynamics in the carotid and vertebrobasilar regions of the brain in patients with cerebral atherosclerosis (rheoencephalographic data)]" 07/01/1976 - "Comparative study of the effect of radon baths of different concentration on the bioelectric activity of the brain and cerebral hemodynamics in patients with cerebral arteriosclerosis with transient disorders of cerebrovascular circulation]" 05/01/1973 - "Mechanism of action of nitrogen baths on brain hemodynamics in cerebral arteriosclerosis (based on rheoencephalographic and mathematical modeling data)]" 03/01/1978 - "Effect of chloride sodium iodobromine baths on the dynamics of the clinical and functional indices in cerebral arteriosclerosis patients]" Get all the results and reference details, order at left...
4.	Electronarcosis (Electrosleep) 04/01/1983 - "Electrosleep in the combined sanatorium and health resort treatment of cerebral arteriosclerosis patients]" 01/01/1969 - "Reactions of the cerebral cortex in patients with incipient cerebral atherosclerosis to the effects of electrosleep and Bourguignon's galvanization (based on electroencephalographic data)]" 01/01/1969 - "Significance of electronarcosis in sanatorium treatment of patients with cerebral arteriosclerosis]" 09/01/1982 - "Effectiveness of the sanatorium and health resort treatment, including massage of the collar area and electrosleep, of early cerebral arteriosclerosis patients with a history of transient cerebral circulatory disorder]" Get all the results and reference details, order at left...
5.	Home Nursing (Nursing, Home) 01/01/1974 - "A double-blind evaluation of 'Hydergine' and placebo in the treatment of patients with organic brain syndrome and cerebral arteriosclerosis in a nursing home." 04/29/2007 - "In our case the disorder was diagnosed in a 69 years old patient, taking clopidogrel, living in a nursing home, with history of hypertension, general arteriosclerosis, cerebral infarction, who was admitted to our department because of melaena and hematemesis" Get all the results and reference details, order at left...
18 Therapies and Procedures and 40 more articles analyzed in the Research Interface, order at left...

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