Cephamycins

Naturally occurring family of beta-lactam cephalosporin-type antibiotics having a 7-methoxy group and possessing marked resistance to the action of beta-lactamases from gram-positive and gram-negative organisms.

Also Known As:

Networked: 82 relevant articles (6 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Lyras, Dena: 2 articles (01/2020 - 12/2019)
2.	McGowan, Sheena: 2 articles (01/2020 - 12/2019)
3.	Liu, Jien-Wei: 2 articles (01/2019 - 09/2011)
4.	Lepeule, Raphaël: 2 articles (12/2018 - 03/2012)
5.	Su, Lin-Hui: 2 articles (09/2011 - 04/2007)
6.	Fan, Zhenxin: 1 article (01/2022)
7.	Feng, Jinyi: 1 article (01/2022)
8.	He, Miao: 1 article (01/2022)
9.	Lan, Weiqi: 1 article (01/2022)
10.	Lan, Yue: 1 article (01/2022)

Related Diseases

1.	Infections 07/01/1995 - "However, cephamycins should be used with caution to treat infections caused by ESBL-producing K. " 11/01/1990 - "Role of new cephamycins in the management of obstetric and gynecologic infections." 11/01/1990 - "Criteria for administering cephamycin therapy were established, as were guidelines for evaluating the progress of the infection. " 10/01/1986 - "Efficacy of CTT, a new cephamycin antibiotic, was studied in 50 cases (39 cases of prophylactic use for postoperative infections and 11 cases of several different infections). " 09/01/2015 - "The most promising candidates for invasive infections so far are β-lactam/β-lactamase inhibitor combinations and cephamycins. "
2.	Urinary Tract Infections (Urinary Tract Infection) 04/01/2007 - "Forty-six cephamycin-resistant Escherichia coli isolates from patients diagnosed with community-acquired urinary tract infection were selected in order to study their resistance mechanism. " 09/01/1997 - "An Escherichia coli strain resistant to a broad spectrum of beta-lactams, including cephamycins, was isolated from a patient suffering from urinary tract infection. " 03/01/2012 - "We investigated the efficiency of the cephamycin cefoxitin as an alternative to carbapenems for the treatment of urinary tract infections (UTIs) due to Escherichia coli producing CTX-M-type extended-spectrum β-lactamases. " 11/01/1985 - "Its efficacy in urinary tract infections is at least as good as cefoxitin, although in this and some other clinical areas its activity relative to that of other cephamycins and cephalosporins remains to be assessed. " 01/01/1985 - "Effects of MT-141, a new cephamycin antibiotic, on acute urinary tract infections."
3.	Sepsis (Septicemia) 01/01/2020 - "Although cephamycins (cefmetazole; CMZ) have been shown to be effective against mild cases of ESBL-E infection, data on their use for severe ESBL-E infections with sepsis or septic shock remain scarce. " 01/01/2020 - "Successful de-escalation antibiotic therapy using cephamycins for sepsis caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae bacteremia: A sequential 25-case series." 03/01/1981 - "Clinical trials of cefoxitin, a new cephamycin antibiotic were carried out on 17 infantile patients with infections (respiratory tract infection 15, meningitis 1 and sepsis 1). " 12/01/2021 - "Here, we present a pentaplex, real-time PCR-based assay that can quickly identify the most common beta-lactamase genes (Klebsiella pneumoniae carbapenemase (KPC); New Delhi metallo-beta-lactamase (NDM); cefotaximase-Munich (CTX-M); cephamycin AmpC beta-lactamases (CMY); and Oxacillinase-48 (OXA-48)) from pathogens derived directly from the blood of patients presenting with bacterial septicemia.Aim" 01/01/2018 - "A systematic literature search using PubMed and MEDLINE databases (January 1, 2012, to June 30, 2017) was performed using key MESH terms: ESBL or extended-spectrum β-lactamases and bacteremia or bloodstream infection with piperacillin/tazobactam, ciprofloxacin, levofloxacin, cefepime, cephamycins, carbapenem, doripenem, meropenem, and ertapenem. "
4.	Bacteremia 01/01/2016 - "Although cephamycins such as cefoxitin, cefmetazole or cefotetan are effective against ESBL-producers in vitro, there are few clinical data demonstrating effects against bacteremia caused by these organisms. " 01/01/2020 - "Successful de-escalation antibiotic therapy using cephamycins for sepsis caused by extended-spectrum beta-lactamase-producing Enterobacteriaceae bacteremia: A sequential 25-case series." 01/01/2018 - "A systematic literature search using PubMed and MEDLINE databases (January 1, 2012, to June 30, 2017) was performed using key MESH terms: ESBL or extended-spectrum β-lactamases and bacteremia or bloodstream infection with piperacillin/tazobactam, ciprofloxacin, levofloxacin, cefepime, cephamycins, carbapenem, doripenem, meropenem, and ertapenem. "
5.	Communicable Diseases (Infectious Diseases) 06/01/1983 - "The tissue specimens were taken to evaluate the efficacy of cefotetan (CTT), a new cephamycin antibiotic, for otorhinolaryngological infectious diseases. " 03/01/1988 - "Cefotetan (CTT), a newly-developed cephamycin antibiotic, has been used widely for the treatment of various infectious diseases because of its excellent antibacterial potency and dynamic transport in vivo. " 05/01/1983 - "T-1982 (cefbuperazone), a new cephamycin antibiotic with broad spectrum against Gram-positive, negative aerobic and anaerobic organisms, was clinically and bacteriologically evaluated on the gynecologic infectious diseases. "

Related Drugs and Biologics

1.	Anti-Bacterial Agents (Antibiotics)
2.	Cefmetazole (Cefmetazole Sodium)
3.	Cefotetan (Cefotan)
4.	Cefoxitin (Cefoxitin Sodium)
5.	cefminox
6.	Moxalactam (Latamoxef)
7.	Cefotaxime (Kendrick)
8.	Cephalosporins (Cephalosporin Antibiotics)
9.	Carbapenems (Carbapenem Antibiotics)
10.	beta-Lactams

Related Therapies and Procedures

1.	Injections
2.	Therapeutics
3.	Intravenous Injections
4.	Hysterectomy