HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Neoplastic Cell Transformation

Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
Also Known As:
Cell Transformation, Neoplastic; Transformation, Neoplastic Cell; Tumorigenic Transformation; Cell Neoplastic Transformation; Cell Neoplastic Transformations; Cell Transformations, Neoplastic; Neoplastic Cell Transformations; Neoplastic Transformations, Cell; Transformation, Cell Neoplastic; Transformation, Tumorigenic; Transformations, Cell Neoplastic; Transformations, Neoplastic Cell; Transformations, Tumorigenic; Tumorigenic Transformations; Neoplastic Transformation, Cell
Networked: 283 relevant articles (2 outcomes, 30 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Carcinoma (Carcinomatosis)
3. Carcinogenesis
4. Skin Neoplasms (Skin Cancer)
5. Chromosomal Instability (Chromosome Stability)

Experts

1. Dong, Zigang: 17 articles (03/2016 - 06/2004)
2. Bode, Ann M: 13 articles (03/2016 - 06/2004)
3. Choi, Hong Seok: 11 articles (10/2018 - 06/2004)
4. Lee, Ki Won: 10 articles (05/2016 - 09/2007)
5. Lee, Hyong Joo: 9 articles (05/2016 - 09/2007)
6. Cho, Yong-Yeon: 8 articles (10/2015 - 06/2004)
7. Heo, Yong-Seok: 6 articles (03/2016 - 11/2007)
8. Kang, Nam Joo: 6 articles (07/2011 - 09/2007)
9. Fusco, Alfredo: 5 articles (01/2019 - 12/2007)
10. Shim, Jung-Hyun: 5 articles (03/2017 - 01/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Neoplastic Cell Transformation:
1. fucoidanIBA
2. Caspase 9IBA
3. Proteins (Proteins, Gene)FDA Link
4. DNA (Deoxyribonucleic Acid)IBA
5. Epidermal Growth Factor (EGF)IBA
6. CarcinogensIBA
7. Phosphotransferases (Kinase)IBA
8. Protein Isoforms (Isoforms)IBA
9. Transcription Factor AP-1 (Transcription Factor AP 1)IBA
10. Oncogene Proteins (Oncogene Protein)IBA

Therapies and Procedures

1. Therapeutics
01/01/2021 - "In addition to the known effects on neoplastic cell transformation, the IL17 cytokine family uniquely affects fibroblasts, representing a suitable candidate target for combinatorial immune-based therapies in PDA."
07/15/2014 - "Herein, we reviewed the recent progress in our understanding of (1) how an "oncogenic nexus" of CIP2A participates in the tumorigenic transformation of cells and (2) how we can prospect/view the clinical relevance of CIP2A in the context of cancer therapy. "
04/01/2003 - "A deeper understanding of the molecular biology of cell growth and proliferation, as well as of neoplastic cell transformation, has led to advances in several areas, including the use of hormones and antihormones as adjuvant therapy; inhibition of tumour growth and metastasis by inhibitors of matrix metalloproteases and angiogenesis, and by small molecules, such as retinoids, which interfere with progression through the cell cycle; immunotherapy with monoclonal antibodies; disruption of intracellular signal transduction with farnesyltransferase inhibitors; and, finally, gene therapy with specifically designed vaccines."
05/01/2000 - "A more profound understanding of the molecular biology of cell growth and proliferation, as well as of neoplastic cell transformation, has led to advances in several areas, including the use of somatostatin analogues and antiandrogens as adjuvant therapy; inhibition of tumour growth and metastasis by inhibitors of matrix metalloproteinases and angiogenesis, and by small molecules such as retinoids, which interfere with progression through the cell cycle; immunotherapy with monoclonal antibodies; disruption of intracellular signal transduction with farnesyltransferase inhibitors; and finally gene therapy with specifically designed vaccines."
2. Immunotherapy
3. Chemoprevention
4. Mammaplasty (Breast Reconstruction)
5. Radiotherapy