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Ceftazidime (Fortum)

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Semisynthetic, broad-spectrum antibacterial derived from CEPHALORIDINE and used especially for Pseudomonas and other gram-negative infections in debilitated patients.

Also Known As:

Fortum; Tazidime; Fortaz; GR-20263; LY-139381; GR 20263; GR20263; LY 139381; LY139381; Pyridinium, 1-((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acetyl)amino)-2-carboxy-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-en-3-yl)methyl)-, inner salt, pentahydrate, (6R-(6alpha,7beta(Z)))-

Networked: 1362 relevant articles (245 outcomes, 265 trials/studies) for this Drug, Comments

Relationship Network

Drug Context: Research Results

Experts

1.	Nicolau, David P: 6 articles (05/2007 - 06/2004)
2.	Currie, Bart J: 4 articles (08/2007 - 05/2004)
3.	Cheng, Allen C: 4 articles (08/2007 - 05/2004)
4.	Kuti, Joseph L: 4 articles (05/2007 - 07/2005)
5.	Ciofu, Oana: 3 articles (04/2010 - 12/2002)
6.	Rosenthal, Victor D: 3 articles (03/2010 - 04/2006)
7.	Rouby, Jean-Jacques: 3 articles (10/2009 - 05/2005)
8.	Peacock, Sharon J: 3 articles (08/2007 - 10/2005)
9.	Chierakul, Wirongrong: 3 articles (08/2007 - 10/2005)
10.	Chaowagul, Wipada: 3 articles (08/2007 - 10/2005)

Related Diseases

1.	Infection 07/01/1994 - "Ceftazidime is a beta-lactam antibiotic highly effective against Pseudomonas aeruginosa infection. " 06/01/1990 - "In conclusion: ceftazidime + vancomycine combination is a very effective treatment of infection in the neutropenic children: 88% success. " 03/01/1990 - "We conclude that there has been an overall improvement in the diagnosis and treatment of MEO and that monotherapy with ceftazidime shows promise against this potentially fatal pseudomonal infection." 11/30/1989 - "Overall, intravenous/oral ciprofloxin therapy appears to be as safe and effective as intravenous ceftazidime therapy in the treatment of a variety of infections due to susceptible aerobic gram-negative organisms." 05/01/2010 - "Ceftazidime, a third-generation cephalosporin, is widely used for the treatment of Pseudomonas aeruginosa infections. " Order ALL the reference details at left...
2.	Pneumonia (Pneumonitis) 08/01/1985 - "An experimental Klebsiella pneumoniae pneumonia in rats was used to study the influence of continuous or of intermittent (8-hr intervals) administration of ceftazidime on therapeutic efficacy. " 06/01/2000 - "Both intermittent and continuous ceftazidime regimens were equally effective for the treatment of nosocomial pneumonia caused by less virulent bacteria." 08/01/1985 - "Therapeutic efficacy of continuous versus intermittent administration of ceftazidime in an experimental Klebsiella pneumoniae pneumonia in rats." 02/01/2009 - "[Study on the blood concentration and clinical efficacy of ceftazidime, a cephem antibiotic at dose of one gram q.i.d, for adult hospital-acquired pneumonia patients]" 06/01/2001 - "A prospective, randomized pilot study was undertaken to compare the efficacy of continuous versus intermittent ceftazidime in ICU patients with nosocomial pneumonia. " Order ALL the reference details at left...
3.	Neoplasms (Cancer) 01/01/2003 - "CONCLUSIONS: Ultra short-term antimicrobial prophylaxis with ceftazidime is safe and effective in patients undergoing surgery for gynecologic cancer." 12/01/2002 - "Continuous infusion of ceftazidime in the empiric treatment of febrile neutropenic children with cancer." 07/01/1986 - "CV appears to be superior to KGC or ceftazidime alone in the management of febrile granulocytopenic cancer patients." 04/01/1985 - "We administered 2 g of ceftazidime intravenously every 8 h to cancer patients for the empiric therapy of febrile episodes. " 08/01/1983 - "Multiple-dose pharmacokinetics of ceftazidime in cancer patients." Order ALL the reference details at left...
4.	Fever (Fevers) 09/01/1999 - "Ceftazidime in combination with a glycopeptide antibiotic provides an effective and safe first-line therapy for patients with neutropenic fever following PBSC-supported high-dose therapy." 10/26/1988 - "In a preliminary study of 21 febrile episodes in neutropenic patients ceftazidime used as empirical treatment in doses of 3 grams per day succeeded in controlling fever in 74 per cent of the cases. " 01/01/2006 - "Twenty-five (66%) patients responded with clinical improvement and complete resolution of fever within 48 h after initiation of ceftazidime therapy. " 07/01/2002 - "Ceftazidime-resistant Enterobacter aerogenes was isolated from blood cultures of three patients with fever. " 02/01/2002 - "Fever responded to treatment with Ceftazidime. " Order ALL the reference details at left...
5.	Cystic Fibrosis (Mucoviscidosis) 12/01/2000 - "Continuous infusion of ceftazidime with a portable pump is as effective as thrice-a-day bolus in cystic fibrosis children." 05/01/1986 - "Ceftazidime appears to be effective and safe, alone or associated with an aminoglycoside, in the treatment of acute exacerbation in cystic fibrosis. " 09/01/2009 - "The present multicenter, randomized crossover study compared the safety and efficacy of continuous infusion with those of short infusions of ceftazidime in patients with cystic fibrosis. " 07/01/1988 - "Influence of the glomerular filtration rate on renal clearance of ceftazidime in cystic fibrosis." 08/01/1983 - "The pharmacokinetics and clinical efficacy of ceftazidime, a cephalosporin with activity against Pseudomonas aeruginosa, were studied in children with cystic fibrosis. " Order ALL the reference details at left...

Related Drugs and Biologics

1.	Amikacin (A.M.K)
2.	cefepime (Maxipime)
3.	Ciprofloxacin (Cipro)
4.	Tobramycin (Nebcin)
5.	meropenem (Merrem)
6.	Vancomycin
7.	Imipenem
8.	Anti-Bacterial Agents (Antibiotics)
9.	Gentamicins (Gentamicin)
10.	Ceftriaxone (Ceftriaxon)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Peritoneal Dialysis
3.	Aftercare (After-Treatment)
4.	Injections
5.	Vitrectomy

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