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Carpal Tunnel Syndrome

Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)
Also Known As:
Amyotrophy, Thenar, Of Carpal Origin; Median Neuropathy, Carpal Tunnel; Carpal Tunnel Syndromes; Syndrome, Carpal Tunnel; Syndromes, Carpal Tunnel; Compression Neuropathy, Carpal Tunnel; Entrapment Neuropathy, Carpal Tunnel
Networked: 1945 relevant articles (183 outcomes, 402 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Pain (Aches)
2. Tendinopathy (Tendonitis)
3. Osteoarthritis
4. Low Back Pain (Lumbago)
5. Tennis Elbow (Elbow, Tennis)

Experts

1. Amadio, Peter C: 19 articles (08/2021 - 11/2004)
2. Wu, Yung-Tsan: 15 articles (06/2022 - 01/2016)
3. Li, Tsung-Ying: 13 articles (06/2022 - 01/2016)
4. Chen, Liang-Cheng: 12 articles (01/2022 - 01/2016)
5. Zhao, Chunfeng: 12 articles (03/2021 - 11/2004)
6. Raeissadat, Seyed Ahmad: 10 articles (01/2020 - 01/2013)
7. Chou, Yu-Ching: 9 articles (01/2022 - 01/2016)
8. Fernández-de-Las-Peñas, César: 9 articles (01/2022 - 11/2010)
9. Ly-Pen, Domingo: 9 articles (01/2022 - 02/2005)
10. An, Kai-Nan: 9 articles (02/2015 - 11/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Carpal Tunnel Syndrome:
1. Adrenal Cortex Hormones (Corticosteroids)IBA
2. SteroidsIBA
3. Lidocaine (Xylocaine)FDA LinkGeneric
4. Vitamin B 6IBA
5. Gabapentin (Neurontin)FDA LinkGeneric
6. Glucose (Dextrose)FDA LinkGeneric
7. Thioctic Acid (Lipoic Acid)IBA
8. salicylhydroxamic acid (SHAM)IBA
9. MethylprednisoloneFDA LinkGeneric
10. Analgesics (Analgesic Drugs)IBA

Therapies and Procedures

1. Splints (Splint)
2. Conservative Treatment
3. Injections
4. Decompression
5. Therapeutics