|1.||Supuran, Claudiu T: 232 articles (12/2015 - 02/2003)|
|2.||Scozzafava, Andrea: 93 articles (04/2015 - 03/2003)|
|3.||Vullo, Daniela: 73 articles (10/2015 - 03/2003)|
|4.||Pastorekova, Silvia: 51 articles (07/2015 - 03/2003)|
|5.||Pastorek, Jaromir: 48 articles (04/2015 - 02/2003)|
|6.||Harris, Adrian L: 40 articles (10/2015 - 08/2002)|
|7.||Winum, Jean-Yves: 39 articles (09/2015 - 05/2003)|
|8.||Innocenti, Alessio: 38 articles (09/2012 - 10/2004)|
|9.||Parkkila, Seppo: 34 articles (05/2015 - 12/2002)|
|10.||Oosterwijk, Egbert: 30 articles (08/2015 - 09/2003)|
07/01/2007 - "Due to characteristic physicochemical properties of sulphonamide (Inhibition of Carbonic Anhydrase), they are clinically effective against glaucoma. "
01/01/2014 - "Inhibition of carbonic anhydrase (CA, EC 220.127.116.11) has pharmacologic applications in the treatment of glaucoma, a disease affecting a large number of people and characterized by an elevated intraocular pressure (IOP). "
07/01/2008 - "In all patients, the IOP increase was sustained across several visits, requiring control with topical glaucoma therapy, and in two cases the addition of a systemic carbonic anhydrase inhibitor. "
10/01/2007 - "Inhibition of carbonic anhydrase in the eye is an important treatment modality for reducing the intraocular pressure in glaucoma. "
10/07/2004 - "Sulfonamide carbonic anhydrase (CA) inhibitors are widely employed in the diagnosis and treatment of diverse diseases such as glaucoma and different neuromuscular disorders. "
|2.||Open-Angle Glaucoma (Glaucoma, Open Angle)
12/01/1999 - "[Ocular pulse amplitude, intraocular pressure and beta blocker/carbonic anhydrase inhibition in combined therapy of primary open-angle glaucoma]."
07/01/1998 - "Topical carbonic anhydrase inhibition increases ocular pulse amplitude in high tension primary open angle glaucoma."
01/01/1998 - "Clinical use of a topical carbonic anhydrase inhibitor in patients affected by chronic simple glaucoma."
10/01/1991 - "For several decades a tantalizing goal for the treatment of primary open-angle glaucoma has been the development of a topically active carbonic anhydrase inhibitor. "
01/15/1989 - "We tested the effect on intraocular pressure of three commonly used oral carbonic anhydrase inhibitor preparations in a controlled, randomized, comparative study on patients with primary open-angle glaucoma. "
01/01/2015 - "A topical cocktail of strong steroid, NSAID, and carbonic anhydrase inhibitor drops are effective for managing cystoid macular edema. "
01/01/2015 - "To report the combination cocktail of strong steroid, non-steroidal anti-inflammatory drug (NSAID), and carbonic anhydrase inhibitor drops for treatment of cystoid macular edema. "
01/01/2015 - "Strong topical steroid, NSAID, and carbonic anhydrase inhibitor cocktail for treatment of cystoid macular edema."
01/01/2013 - "The purpose of this study was to evaluate prospectively the efficacy of a topical carbonic anhydrase inhibitor in macular edema after vitrectomy. "
01/01/2015 - "Focal photocoagulation interrupts vascular leakage in diabetic macular edema, and allows the retinal pigment epithelium to withdraw fluid that thickens the retina; this mechanism could be enhanced by dorzolamida, a topical carbonic anhydrase inhibitor. "
07/01/2013 - "To study the expression of carbonic anhydrase IX (CAIX), PAX2 and PAX8 in different types of renal epithelial tumor and their association with clinicopathologic characteristics. "
02/01/2011 - "Numerous studies over the past decade involving the cancer-specific carbonic anhydrase IX have re-kindled an interest in pH disruption-based therapies. "
03/01/2010 - "Prognostic relevance of carbonic anhydrase-IX in high-risk, early-stage cervical cancer: a Gynecologic Oncology Group study."
04/01/2009 - "The carbonic anhydrase isoenzyme CA IX was selected for further studies due to its expression on the surface of many types of hypoxic tumors. "
11/01/2007 - "Carbonic anhydrase (CA) IX is a very interesting subject for study due to its overexpression in cancer and its expression in very few normal tissues. "
|5.||Renal Cell Carcinoma (Grawitz Tumor)
05/01/2014 - "The PET tracer, (124)I-cG250, directed against carbonic anhydrase IX (CAIX) shows promise for presurgical diagnosis of clear-cell renal cell carcinoma (ccRCC) (Divgi et al. in Lancet Oncol 8:304-310, 2007; Divgi et al. in J Clin Oncol 31:187-194, 2013). "
04/01/2015 - "High expression of carbonic anhydrase IX (CA IX) has been reported in clear cell renal cell carcinoma (ccRCC); few studies have reported CA IX expression in other tumours with predominantly clear cell morphology. "
12/01/2014 - "In a clinical study in advanced renal cell carcinoma (RCC) patients with CAR T cells specific for carbonic anhydrase IX (CAIX), we observed toxicities that (most likely) indicated in vivo function of CAR T cells as well as low T cell persistence and clinical response rates. "
10/01/2012 - "This study aimed to evaluate the usefulness of carbonic anhydrase IX (CA-IX) expression in clear cell renal cell carcinoma (CCRCC) using two different techniques to detect protein expression. "
01/01/2012 - "High immunohistochemical expression of carbonic anhydrase IX (CAIX) is found in clear cell renal cell carcinoma (ccRCC), but no studies have assessed CAIX in metastatic ccRCC (mccRCC) of the lung. "
|4.||Protein Isoforms (Isoforms)
|8.||Carbonic Anhydrase Inhibitors