Carbon Monoxide

Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed)

Also Known As:

Networked: 5734 relevant articles (168 outcomes, 521 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Otterbein, Leo E: 42 articles (01/2021 - 11/2002)
2.	Choi, Augustine M K: 38 articles (12/2020 - 11/2002)
3.	Motterlini, Roberto: 28 articles (01/2022 - 07/2003)
4.	Ryter, Stefan W: 27 articles (11/2020 - 11/2003)
5.	Hampson, Neil B: 26 articles (12/2019 - 03/2002)
6.	Nakao, Atsunori: 24 articles (01/2022 - 10/2003)
7.	Weaver, Lindell K: 23 articles (01/2022 - 02/2002)
8.	Nielsen, Vance G: 22 articles (01/2018 - 07/2009)
9.	Wells, Athol U: 18 articles (12/2021 - 02/2004)
10.	Goebel, Ulrich: 15 articles (01/2020 - 06/2008)

Related Diseases

1.	Poisoning 01/01/2002 - "Since the changeover in the gas used in domestic appliances, the prevalence of acute carbon monoxide (CO) poisoning has been dramatically reduced. " 01/01/2018 - "Recent public health strategies have contributed towards a significant reduction in the incidence of carbon monoxide (CO) poisonings. " 01/01/2005 - "While the overall death rate from unintentional carbon monoxide (CO) poisoning has decreased in the United States due to improved automobile emissions controls and a decline in CO poisonings from motor vehicles, exposures have not changed from some sources of CO. " 10/15/2016 - "This study was designed to determine the protective effects of methane-rich saline (MRS) on acute carbon monoxide (CO) poisoning. " 06/01/2018 - "Delayed onset of neuropsychiatric symptoms after apparent recovery from acute carbon monoxide (CO) poisoning has been described as delayed neuropsychiatric sequelae (DNS). "
2.	Inflammation (Inflammations) 01/01/2010 - "Recent studies have suggested that exogenously administered carbon monoxide (CO) is beneficial for resolution of acute inflammation. " 11/14/2022 - "Carbon monoxide (CO) is a bioactive molecule with high potential as it shows promising efficacy for regulating inflammation. " 01/01/2021 - "Carbon monoxide-releasing molecule (CORM)-3 is a water-soluble exogenous carbon monoxide that exerts protective effects against inflammation-induced pyroptosis. " 01/01/2016 - "Low concentrations of exogenous carbon monoxide (CO) have been reported to be useful for the treatment of various disorders related to inflammation and oxidative stress. " 01/01/2012 - "Several reports have described the role of carbon monoxide (CO) in protection against chronic intestinal inflammation. "
3.	Reperfusion Injury 01/01/2019 - "Carbon monoxide (CO) releasing molecule (CORM)-3, a water-soluble CORM, has protective effects against inflammatory and ischemia/reperfusion injury. " 01/01/2017 - "Carbon monoxide (CO) exerts protective effects on hepatic ischemia/reperfusion injury (IRI), but the underlying molecular mechanisms are not fully understood. " 01/01/2021 - "through the use of low levels of carbon monoxide (CO), has promise in preventing ischemia-reperfusion injury and cell death. " 11/01/2009 - "Liver graft exposure to carbon monoxide during cold storage protects sinusoidal endothelial cells and ameliorates reperfusion injury in rats." 11/01/2021 - "Measurements of the fraction of carbon monoxide in exhaled gas (FECO) confirm levels recorded during previous studies driven to evaluate FECO as a potential marker of ischemia reperfusion injuries. "
4.	Hypoxia (Hypoxemia) 01/01/2012 - "These patients have a characteristic lung function profile, with unexpected subnormal dynamic and static lung volumes, contrasting with a significant reduction of carbon monoxide transfer (DL(co)) and exercise hypoxemia. " 12/01/2010 - "These patients have a characteristic lung function profile, with dynamic and static lung volumes apparently normal or minimally altered, contrasting with a significant reduction of carbon monoxide transfer (DLco) and exercise hypoxemia. " 01/01/2022 - "A total of 65 subjects participated in this study: 30 subjects were exposed to poikilocapnic hypoxia, 14 were exposed to isocapnic hypoxia, and 21 were exposed to carbon monoxide (CO). " 01/01/2021 - "Mechanistic studies showed that carbon monoxide stabilized HIF-1α in Hmox1-/- fibroblasts in response to hypoxia. " 03/01/2001 - "This study was designed to investigate whether exposure to carbon monoxide (CO) could alter the ischemic tolerance induced by chronic hypoxia. "
5.	Chronic Obstructive Pulmonary Disease (COPD) 12/01/1977 - "Breathing 100 ppm of carbon monoxide for 1 hour caused a significant reduction in exercise performance in patients with chronic obstructive pulmonary disease." 11/01/2016 - "COPD patients with severe diffusion defect in carbon monoxide diffusing capacity predict a better outcome for pulmonary rehabilitation." 01/01/2021 - " studies were identified by searching the terms "diffusing capacity" OR "diffusing capacity for carbon monoxide" or "DLCO" AND "COPD" AND "assessment" in Pubmed, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, Scopus, and Web of Science databases. " 11/01/2016 - "The aim of this study was to compare the effects of pulmonary rehabilitation (PR) on six-minute walk test (6mWT) between chronic obstructive pulmonary disease (COPD) patients with moderate or severe carbon monoxide diffusion defects. " 12/15/2014 - "We conducted a time-series study in Hong Kong to estimate the association of short-term exposure to ambient carbon monoxide with emergency hospitalizations for COPD. "

Related Drugs and Biologics

1.	Oxygen (Dioxygen)
2.	Heme Oxygenase (Decyclizing) (Heme Oxygenase)
3.	Bilirubin
4.	Iron
5.	Enzymes
6.	Biliverdine (Biliverdin)
7.	Heme (Haem)
8.	Lipopolysaccharides
9.	Nitric Oxide (Nitrogen Monoxide)
10.	Carboxyhemoglobin

Related Therapies and Procedures

1.	Therapeutics
2.	Resuscitation
3.	Hyperbaric Oxygenation
4.	Drug Therapy (Chemotherapy)
5.	Aftercare (After-Treatment)