|1.||Reichmann, Heinz: 3 articles (06/2011 - 08/2006)|
|2.||Gille, Gabriele: 3 articles (06/2011 - 08/2006)|
|3.||Cook, James M: 2 articles (10/2015 - 11/2010)|
|4.||Lehmann, Jochen: 2 articles (08/2015 - 11/2006)|
|5.||Enzensperger, Christoph: 2 articles (08/2015 - 06/2010)|
|6.||Haghdoost-Yazdi, Hashem: 2 articles (09/2012 - 12/2010)|
|7.||Faraji, Ayda: 2 articles (09/2012 - 12/2010)|
|8.||Polanski, Witold: 2 articles (06/2011 - 06/2010)|
|9.||Rommelspacher, Hans: 2 articles (11/2006 - 08/2006)|
|10.||God, Ralf: 2 articles (07/2006 - 05/2002)|
01/01/2007 - "From the behavioral pharmacology of beta-carbolines to seizures, anxiety, and memory."
11/25/1991 - "Thus, myoclonic seizures seem to be the most appropriate index for evaluating the convulsant action of beta-carbolines in genetic experiments."
11/25/1991 - "Comparisons between patterns of convulsions induced by two beta-carbolines in 10 inbred strains of mice."
09/01/1987 - "Bidirectional effects of beta-carbolines in rats with spontaneous petit mal-like seizures."
11/01/1983 - "One such group of compounds, the beta-carbolines, cause convulsions, produce an anxiety-like syndrome in primates, and reduce sleep. "
|2.||Parkinson Disease (Parkinson's Disease)
09/01/2012 - "β-Carbolines (BCs) are considered to be endogenous toxins and have been proposed as possible causative candidates inducing Parkinson's disease (PD). "
12/01/2006 - "beta-Carbolines structurally related to the selective dopaminergic neurotoxin 1-methyl-4- phenylpyridinium (MPP(+)) may contribute to dopaminergic neurodegeneration in Parkinson's disease. "
08/01/2006 - "beta-Carbolines are potential endogenous and exogenous neurotoxicants that may contribute to the pathogenesis of Parkinson's disease. "
02/01/2004 - "The role of long-term exposure to food-related beta-carbolines and a retention of these compounds in pigment-containing neurons in the induction of idiopathic Parkinson's disease should be further considered."
01/01/2003 - "The endogeneous formation of highly chlorinated tetrahydro-beta-carbolines as a possible causative mechanism in idiopathic Parkinson's disease."
|3.||Alcoholism (Alcohol Abuse)
01/01/1982 - "A GC-MS study on the occurrence of two tetrahydro-beta-carbolines implicated in alcoholism."
10/28/2015 - "Synthesis of aza and carbocyclic β-carbolines for the treatment of alcohol abuse. "
03/26/2004 - "The proposed method will be useful for detecting the in vivo concentration changes of beta-carbolines associated with alcohol abuse, smoking behavior and neuropsychiatric disorder."
11/01/2010 - "A series of 3,6-disubstituted β-carbolines was synthesized and evaluated for their in vitro affinities at α(x)β(3)γ(2) GABA(A)/benzodiazepine receptor subtypes by radioligand binding assays in search of α(1) subtype selective ligands to treat alcohol abuse. "
03/01/1996 - "Tetrahydro-beta-carbolines, formed from aldehydes and tryptamine, have been suggested as potential biochemical markers for alcoholism. "
|4.||Alzheimer Disease (Alzheimer's Disease)
05/01/1988 - "beta-Carbolines for Alzheimer's disease?--more evidence, a test of efficacy and some precautions."
01/01/1988 - "Treatment strategies for senile dementia: antagonist beta-carbolines."
11/15/2006 - "In the course of studies directed toward the discovery of novel acetyl- and butyrylcholinesterase (AChE and BChE) inhibitors for the treatment of Alzheimer's disease, we focused on beta-carbolines (BCs). "
04/01/2011 - "Synthesis of carbon-11-labeled bivalent β-carbolines as new PET agents for imaging of cholinesterase in Alzheimer's disease."
01/01/2015 - "Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease."
01/01/2001 - "In this study, structural significance among these carbolines was investigated in relation to the types of cell death, apoptosis and necrosis, using human neuroblastoma SH-SY5Y cells. "
11/01/1997 - "The natural beta-carbolines facilitate inositol phosphate accumulation by activating small G-proteins in human neuroblastoma cells (SH-SY5Y)."
|1.||methyl 6,7- dimethoxy- 4- ethyl- beta- carboline- 3- carboxylate
|2.||beta-carboline-3-carboxylic acid methyl ester
|6.||Kainic Acid (Kainate)
|8.||Anticonvulsants (Antiepileptic Drugs)