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Carbocysteine (S-Carboxymethylcysteine)

A compound formed when iodoacetic acid reacts with sulfhydryl groups in proteins. It has been used as an anti-infective nasal spray with mucolytic and expectorant action.
Also Known As:
S-Carboxymethylcysteine; 3-(Carboxymethylthio)alanine; Carbocysteine, L-Isomer; Mucodine; Mucodyne; Mukodin; Rhinathiol; S-(Carboxymethyl)-L-cysteine; Thiodril; Carbocysteine, L Isomer; L-Isomer Carbocysteine; S Carboxymethylcysteine; Carboxymethylcysteine; Cysteine, S-(carboxymethyl)-
Networked: 73 relevant articles (14 outcomes, 20 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Steventon, Glyn B: 4 articles (02/2010 - 12/2004)
2. Di Vincenzo, Serena: 3 articles (03/2014 - 11/2013)
3. Gjomarkaj, Mark: 3 articles (03/2014 - 11/2013)
4. Ferraro, Maria: 3 articles (03/2014 - 11/2013)
5. Gerbino, Stefania: 3 articles (03/2014 - 11/2013)
6. Lanata, Luigi: 3 articles (03/2014 - 11/2013)
7. Pace, Elisabetta: 3 articles (03/2014 - 11/2013)
8. Chalumeau, Martin: 3 articles (01/2013 - 01/2009)
9. Mitchell, Stephen C: 3 articles (02/2010 - 11/2006)
10. Duijvestijn, Yvonne C M: 2 articles (01/2013 - 01/2009)

Related Diseases

1. Chronic Obstructive Pulmonary Disease (COPD)
2. Otitis Media with Effusion
3. Obstructive Lung Diseases (Obstructive Lung Disease)
4. Sinusitis
01/01/1997 - "S-carboxymethylcysteine (S-CMC) has been shown to directly enhance the ciliary activity of the chronic sinusitis mucosa. "
09/01/1993 - "Effect of S-carboxymethylcysteine on ciliary activity in chronic sinusitis."
08/01/1985 - "[Effects of carbocysteine on experimental chronic sinusitis caused by long-term exposure to SO2]."
01/01/1997 - "Since s-carboxymethylcysteine (S-CMC) can directly enhance the ciliary activity in the maxillary sinus mucosa of patients with chronic sinusitis in the absence of significant organic changes of ciliated cells, the nebulization therapy using this medicine might be more effective in the treatment of chronic sinusitis than oral administration of the medicine. "
09/01/1992 - "Ancillary therapies of sinusitis could be directed toward (1) preventing viral upper respiratory tract infections (immunizations, virucidal-impregnated tissues, and proper hand-washing techniques); (2) blocking rhinoviral replication and suppressing mediator release with supraphysiologic nasal hyperthermia, although contradictory studies exist with regard to efficacy; (3) promoting sinus and nasal ventilation with both topical and oral alpha-agonists and exercise; (4) improving mucociliary clearance by reducing mucus viscosity and elasticity with saline solution irrigation, mucoregulators (N-acetylcysteine, S-carboxymethylcysteine, and iodinated glycerol), and ciliary stimulants (adenosine triphosphate); and (5) suppressing/modulating cellular inflammation (eosinophilic, basophilic, and neutrophilic) with topical nasal corticosteroid sprays and mediator antagonists. "
5. Lung Diseases (Lung Disease)

Related Drugs and Biologics

1. sobrerol
2. Lysine (L-Lysine)
3. Clarithromycin (Biaxin)
4. Ambroxol (Mucosolvan)
5. carbocysteine-lysine
6. Carbocysteine (S-Carboxymethylcysteine)
7. Acetylcysteine (Siran)
8. Phenylephrine (Neo-Synephrine)
9. Pseudoephedrine
10. Triprolidine (Actidil)

Related Therapies and Procedures

1. Oral Administration
2. Aftercare (After-Treatment)