Carbocyanines

06/01/2004 - "This study suggested that carbocyanine labeled LDL could be used for optical imaging of tumors overexpressing LDLr."
03/01/2023 - "Along with bright fluorescence in the near-IR range, heptamethine carbocyanine dyes possess affinity to cancer cells. "
10/01/2019 - "Further, diethylthiatri carbocyanine iodide attached [email protected] NPs exhibited intense surface-enhanced Raman scattering signals and were used for Raman imaging of MCF7 cells and Raman biosensing in MCF7 tumor-bearing mice. "
06/01/2016 - "By developing and applying a carbocyanine-dye-compatible clearing protocol for observation of cells in deep tissues, we showed that U87 and U373 GBM cells rapidly aggregated into tumor masses in the ventricles and midbrain hemispheres of the zebrafish embryo brain, and invaded the central nervous system, often using the ventricular system and the central canal of the spinal cord. "
10/30/2014 - "Heptamethine carbocyanine dye-mediated near-infrared imaging of canine and human cancers through the HIF-1α/OATPs signaling axis."

02/17/2020 - "Mediated Imaging and Improved Targeting of Farnesylthiosalicylic Acid Delivery for Pancreatic Cancer via Conjugation with Near-Infrared Fluorescence Heptamethine Carbocyanine Dye."

02/01/2015 - "Near‑infrared fluorescence imaging of prostate cancer using heptamethine carbocyanine dyes."
01/01/2014 - "Detection of live circulating tumor cells by a class of near-infrared heptamethine carbocyanine dyes in patients with localized and metastatic prostate cancer."
01/01/2021 - "G10, a tumor‑targeting representative conjugate of heptamethine carbocyanine dye and an inhibitor of MAOA, was shown to exert potent cytotoxic effects, comparable to those of doxorubicin, against prostate cancer cell lines, as well as moderate MAOA inhibitory activity. "
01/01/2020 - "Application of novel pH sensitive isoniazid-heptamethine carbocyanine dye conjugates against prostate cancer cells."
10/30/2014 - "This study explored the specific uptake and retention of a NIR heptamethine carbocyanine MHI-148 dye by canine cancer cells and tissues and human prostate cancer (PCa) specimens and also the dye uptake mechanisms. "

07/01/2007 - "The aim of this study was to test a novel modified single chain anti-ED-B antibody (scFv) conjugated for near infrared fluorescence imaging (NIRF) with tetrasulfonated carbocyanine-maleimide (TSC-scFv) and to examine the association of ED-B with the presence of macrophages in a murine model of atherosclerosis. "

09/26/2007 - "Using DTMRI, immunohistochemistry, and carbocyanine dye tract-tracing studies, we analyzed the Probst bundles in both Netrin1 and deleted in colorectal cancer (DCC) mutant mice. "