|1.||Miyakoshi, Yuichi: 1 article (09/2006)|
|2.||Toyama, Yoshimitsu: 1 article (09/2006)|
|3.||Ikehata, Masateru: 1 article (09/2006)|
|4.||Shimizu, Hidesuke: 1 article (09/2006)|
|5.||Yoshioka, Hayato: 1 article (09/2006)|
|6.||Suzuki, Yuji: 1 article (09/2006)|
|7.||Morimoto, Ken: 1 article (12/2003)|
|8.||Koh, Masae: 1 article (12/2003)|
|9.||Begleiter, A: 1 article (11/2000)|
|10.||Hatake, K: 1 article (07/2000)|
02/01/1984 - "Based on these effects of antibody on tumor cell growth, sequential administration of antibody followed by an anticancer drug (carboquone) was proven to be the most effective immunochemotherapeutic schedule for tumor bearing rats, showing 25-33% long-term survival in comparison with any other controls."
05/01/1982 - "The effect of carboquone (CQ) by intraperitoneal administration on the development of urinary bladder tumors in Wistar strain male rats induced by N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) was studied. "
05/01/1982 - "[Effect of carboquone (esquinone) on the development of urinary bladder tumors in rats induced by N-butyl-N-(4-hydroxybutyl) nitrosamine]."
03/01/1982 - "[Effect of carboquone in complete regression of mouse mammary cancer MM-46]."
11/01/1974 - "[Absorption, distribution, excretion and metabolism of carbazilquinone; a new anti-tumor agent, in mice (author's transl)]."
|2.||Urinary Bladder Neoplasms (Bladder Cancer)
01/01/1981 - "On the results of tests performed to establish the drug concentration required to achive a 50% inhibition of cell survival, carbazilquinone was chosen for the prevention of recurrences of bladder cancer. "
07/01/1979 - "Prophylactic effects of periodic intravesical Carboquone were also indicated in 7 of 8 patients who had experienced recurring superficial bladder tumors."
05/01/1977 - "[Chemotherapy of bladder neoplasms--instillation of carboquone into the bladder]."
01/01/1985 - "Responses of bladder cancer in ACI rats to combination therapy with an immunomodulator, PSK, and an alkylating agent, carboquone, are reported. "
01/01/1981 - "Anticancer drug sensitivity in vitro in the bladder cancer cell line, KK-47 and prophylactic use of carbazilquinone and urokinase in bladder cancer."
|3.||Colorectal Neoplasms (Colorectal Cancer)
08/01/1991 - "Sarcoma-180 cells and human colorectal tumor cells under in vitro hypoxic conditions are more sensitive to mitomycin C and carboquone."
08/01/1991 - "The effects of oxygen concentration on the chemosensitivity of mouse sarcoma-180 (S-180) cells and human colorectal cancer tissues to mitomycin C (MMC) or carboquone (CQ) were determined in vitro, since evidence had been obtained that these drugs are more effective in HeLa cells. "
05/01/1998 - "The results of the chemosensitivity assay are as follows: 5-FU seems to be the most beneficial for primary colorectal cancer; carboquone (CQ), etoposide (VP-16), 5-FU, and mitomycin-C (MMC) for nodal metastasis; CQ, cisplatin (CDDP), 5-FU, adriamycin (ADR) and VP-16 for malignant effusion; and VP-16, CDDP and CQ for liver metastasis. "
05/01/1986 - "Among 9 chemotherapeutic drugs tested, ara-C, 5-fluorouracil, and mitomycin C showed the high percentages of positive sensitivity for gastric cancer, whereas actinomycin D, carboquone, and nimustine hydrochloride were sensitive in case of colorectal cancer. "
04/01/1986 - "Among 9 chemotherapeutic agents tested, ara-C, 5-fluorouracil, and mitomycin C had higher percentages of positive sensitivity for stomach cancer, whereas actinomycin D, carboquone, and ACNU had a more pronounced effect on colorectal cancer. "
|4.||Stomach Neoplasms (Stomach Cancer)
03/01/1982 - "However, it was as sensitive to Carboquone as high-sensitive gastric cancer cell lines. "
09/01/1987 - "A randomized controlled study was carried out on curatively resected gastric cancer patients in a cooperative study involving 16 institutions in order to evaluate the effect of an alternative long-term adjuvant immunochemotherapy using Esquinon (CQ) and Krestin (PSK). "
02/01/1986 - "[Clinical results of a randomized controlled trial on the effect of adjuvant immunochemotherapy using Esquinon and Krestin in patients with curatively resected gastric cancer. "
08/01/1988 - "[Clinical study of combination chemotherapy using carboquone, cisplatin, UFT and OK-432 in 7 cases of advanced gastric cancers and a relapsed gastric cancer]."
08/01/1988 - "In 8 cases of advanced and/or relapsed gastric cancer (7 cases advanced, 1 case relapsed), we undertook combination chemotherapy with systemic administration of cisplatin and celiac arterial infusion of carboquone intermittently under continuous administration of OK-432 i.m. "
03/01/1982 - "Therapeutic index of the Carboquone in the undifferentiated carcinoma was high. "
12/01/1979 - "Antitumor effect of thermodifferential chemotherapy with carboquone on Ehrlich carcinoma."
01/01/1982 - "IV. Enhancement of antitumor activity of carboquone against Ehrlich ascites carcinoma by encapsulation."
01/01/1991 - "A total of 103 patients with advanced gastric carcinoma were randomized after curative surgery to receive an alternate administration of carbazilquinone (CQ) and PSK (Krestin) or carbazilquinone alone. "
01/01/1991 - "Alternating immunochemotherapy of advanced gastric carcinoma: a randomized comparison of carbazilquinone and PSK to carbazilquinone in patients with curative gastric resection."
|1.||Drug Therapy (Chemotherapy)
|4.||Combination Drug Therapy (Combination Chemotherapy)
|5.||Heterologous Transplantation (Xenotransplantation)