Cantharidin (Cantharides)

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285 relevant articles (12 outcomes, 32 trials/studies) found for this Bio-Agent

Description: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.

Also Known As:

Cantharides; Cantharidine; 4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)-

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Efferth, Thomas: 3 articles (01/2007 - 03/2005)
2.	Kahl, Stefan: 2 articles (01/2007 - 03/2005)
3.	Bauer, Rudolf: 2 articles (01/2007 - 03/2005)
4.	Rauh, Rolf: 2 articles (01/2007 - 03/2005)
5.	Kaina, Bernd: 2 articles (01/2007 - 03/2005)
6.	Wong, Raymond Siu Ming: 2 articles (05/2006 - 01/2006)
7.	Chui, Chung Hin: 2 articles (05/2006 - 01/2006)
8.	Lam, Wing Sze: 2 articles (05/2006 - 01/2006)
9.	Lau, Fung Yi: 2 articles (05/2006 - 01/2006)
10.	Cheng, Gregory Yin Ming: 2 articles (05/2006 - 01/2006)

Related Diseases

1.	Warts (Wart) 01/01/2009 - "CONCLUSION: Cantharidin is safe and effective when applied to flat warts without occlusion for 4-6 hours every 3 weeks till clear." 01/01/2009 - "BACKGROUND: Topical cantharidin has been reported to be effective and safe in the treatment of cutaneous warts but it has not previously been used for the treatment of facial flat warts. " 07/01/1960 - "-six per cent of digital warts and 33 per cent of periungual warts cleared after a single application of cantharidin. " 01/01/2009 - "Cantharidin treatment for recalcitrant facial flat warts: a preliminary study." 01/01/2009 - "OBJECTIVE: To evaluate the efficacy and safety of topical cantharidin in the treatment of recalcitrant facial flat warts. " Order ALL the reference details at left...
2.	Blister (Bulla) 07/01/2003 - "We report the blister induction technique and resolution time in ten volunteers enrolled in a pharmacokinetic study using the cantharidin-induced inflammatory blister technique." 01/01/2002 - "The cantharidin blister method was used to study the permeability of capillary vessels. " 06/01/1988 - "The mode of action of cantharidin, the natural vesicant of blister beetles, is examined by radioligand binding studies with mouse tissues. " 01/01/1969 - "3. Enzyme studies of the blister substance in cantharidin blisters]" 01/01/1962 - "[Chemical studies on blister contents in bullous diseases and in cantharidin blisters.]" Order ALL the reference details at left...
3.	Molluscum Contagiosum 03/01/2009 - "CONCLUSIONS: The results contribute to the data supporting cantharidin as a safe and effective treatment of molluscum contagiosum. " 08/01/1979 - "Cantharidin in either a 0.9% or 0.7% solution is a safe and effective office treatment for molluscum contagiosum. " 07/01/2009 - "Cantharidin is cited often in the dermatology and pediatric literature as a valuable treatment option for molluscum contagiosum (MC). " 07/01/2009 - "Cantharidin use among pediatric dermatologists in the treatment of molluscum contagiosum." 10/01/2001 - "Cantharidin therapy for molluscum contagiosum in children." Order ALL the reference details at left...
4.	Pain (Aches) 08/01/2009 - "Topical cantharidin applications are used for the treatment of severe chronic lumbar pain in traditional European medicine (TEM). " 07/01/2009 - "Ninety-two percent of respondents reported satisfaction with cantharidin's efficacy, but 79% reported side effects, with discomfort/pain and blistering being the most common. " 04/01/2006 - "The multimodal CAM treatment resulted in a rapid clinical and x-ray resolution of pneumonia, and cantharidin treatment effectively relieved pain. " 08/01/2009 - "CONCLUSION: In this first study on the efficacy of cantharidin blisters, a clinically relevant pain-relieving short-term effect on LSS was observed. " 08/01/2009 - "We tested the pain-relieving effect of lumbar cantharidin blisters in a non-randomised controlled pilot study. " Order ALL the reference details at left...
5.	Poisoning 10/28/1978 - "Whereas all 5 patients recovered completely, some deaths due to cantharidin poisoning have been reported in the literature. " 03/15/2009 - "However, considerable individual variation in the cantharidin concentration was observed and values of more than 6 mg of this compound per beetle were measured pointing to the high risk of severe and even fatal poisoning when ingesting these insects." 10/01/2001 - "A comprehensive discussion of the origins, folk uses, current FDA status, current dermatologic uses, and effects of cantharidin poisoning has been compiled herein. " 01/01/1998 - "Cantharidin poisoning of emu chicks by ingestion of Pyrota insulata." 10/15/1997 - "In fatal poisonings, gross lesions may be minimal or inapparent, and diagnosis must be confirmed by chemical detection of cantharidin in urine, blood, or stomach or cecal contents." Order ALL the reference details at left...

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8.	Iodized Oil (Lipiodol)
9.	Interleukin-2 (IL2)
10.	Interferons

Related Therapies and Procedures

1.	Cryotherapy (Therapy, Cold)
2.	Cardiopulmonary Bypass (Heart-Lung Bypass)
3.	Chinese Traditional Medicine (Traditional Chinese Medicine)
4.	Drug Therapy (Chemotherapy)
5.	Curettage

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