Campylobacter Infections (Campylobacter Infection)

02/01/2023 - "Our results show that campylobacteriosis was found prevalent among broilers in North Lebanon, making them potential carriers of Campylobacter spp. Future studies should include antibiotic susceptibility testing to check the susceptibility pattern of isolates."
01/01/2022 - "The treatment approach of Campylobacter infection must consider the sensitivity profile of antibiotics as indicated in the study. "
06/30/2021 - "Given the anti-pathogenic and immune-modulatory properties of AC in this study, a short-term application of this non-toxic drug constitutes a promising antibiotics-independent option for the treatment of human campylobacteriosis."
03/11/2021 - "This resistance pattern of Campylobacter found in this study is critically alarming owing to the insusceptibility to the aforementioned antibiotics commonly used as the drugs of choice for campylobacteriosis treatment. "
01/01/2021 - "The results of this study suggest that practitioners should ask about puppy exposure when treating patients with Campylobacter infection, especially when they do not improve with routine antibiotics, and that the commercial dog industry should take action to help prevent the spread of extensively drug-resistant C jejuni from pet store puppies to people."

01/01/2019 - "The rapid dissemination of the macrolide resistance gene erm(B) will likely compromise the efficacy of macrolides as the treatment of choice for campylobacteriosis. "
01/01/2023 - "Nearly a third of the isolates possessed antimicrobial resistance genes, including the ermA resistance gene, potentially conferring resistance to macrolides, the treatment of choice for severe human campylobacteriosis. "
09/02/2022 - "High rates of resistance to classes of antimicrobials critically important for treating Campylobacter infections in humans; fluroquinolones and macrolides, affirm the need for stronger regulatory control of antimicrobials and enhanced antimicrobial stewardship in chicken production."
12/01/2020 - "This novel mechanism of macrolide resistance is a major concern both for human and animal health and warrants close surveillance as macrolides are often the drug of choice for treating campylobacteriosis. "
12/01/2020 - "However, there was no resistance to the macrolides tested which are recommended for the treatment of human campylobacteriosis. "

07/30/2021 - "Since clinical features of human campylobacteriosis are more complicated than the avians, we explored the potential of Hcp as a T6SS targeted vaccine in a murine model as a more reliable and reproducible experimental host to study vaccine-induced immune-protection against C. "
06/01/2011 - "Results suggested that vaccine B or an autogenous product may be effective in controlling ovine campylobacteriosis caused by this emergent abortifacient strain. "
10/01/2012 - "Important considerations will be illustrated using a vaccination trial of a new campylobacter vaccine candidate developed to reduce the numbers of campylobacter in chickens and consequently the numbers of human campylobacteriosis cases. "
11/15/2009 - "Campylobacter jejuni strain CG8421: a refined model for the study of Campylobacteriosis and evaluation of Campylobacter vaccines in human subjects."
11/30/2023 - "In this present issue of the Biomedical Journal insights into pediatric campylobacteriosis are granted, and a potential path to developing a parenteral vaccine against enterotoxigenic E. "

01/01/2009 - "Overall, erythromycin, which is the drug of choice for treatment of Campylobacter infections in humans, is effective in vitro against 97% of chicken isolates in Grenada."
06/01/1984 - "Double-blind placebo-controlled trial of erythromycin in the treatment of clinical campylobacter infection."
02/01/2019 - "coli from humans were resistant also to erythromycin, leaving few options for treatment of severe Campylobacter infections. "
02/01/2019 - "Thus, erythromycin may be considered as the first choice for treatment of Campylobacter infections in this geographical region when indicated."
01/01/2019 - "Apart from three isolates that demonstrated intermediate resistance, all of the isolates were susceptible to erythromycin, which is the drug of choice for treating Campylobacter infections."

01/01/2020 - "Results of recent studies suggested carvacrol (4-isopropyl-2-methylphenol) as potential candidate molecule for the treatment of campylobacteriosis in humans and for the prevention of Campylobacter colonization in farm animals. "
01/01/2023 - "In conclusion, our preclinical placebo-controlled intervention study provides evidence that therapeutic carvacrol application constitutes a promising option to alleviate campylobacteriosis in the infected vertebrate host."
01/01/2023 - "To test the disease-alleviating effects of oral carvacrol treatment in acute murine campylobacteriosis, IL-10-/- mice harboring a human gut microbiota were perorally infected with C. "
01/01/2023 - "Therapeutic Oral Application of Carvacrol Alleviates Acute Campylobacteriosis in Mice Harboring a Human Gut Microbiota."
01/01/2020 - "jejuni loads and alleviated symptoms observed in the here applied clinical murine model for human campylobacteriosis highlight the application of carvacrol as a promising novel option for both, the treatment of campylobacteriosis and hence, for prevention of post-infectious sequelae in humans, and for the reduction of C. "

09/17/2019 - "Moreover, this study revealed virulent properties of Campylobacter isolated from such food products and high resistance rates to fluoroquinolones, which may represent difficulties in campylobacteriosis treatment."
04/15/2004 - "This study provides additional evidence that poultry is an important source of domestically acquired fluoroquinolone-resistant Campylobacter infection. "
12/01/2022 - "The continued emergence of Campylobacter jejuni strains resistant to fluoroquinolones (FQs) has posed a significant threat to global public health, leading frequently to undesirable outcomes of human campylobacteriosis treatment. "
11/11/2022 - "Fluoroquinolones are often used to treat complicated human campylobacteriosis and strains of Campylobacter spp. resistant to these drugs are emerging along the food chain. "
01/01/2021 - "Fluoroquinolones are often the drug of choice for treatment of campylobacteriosis; however, resistance to these drugs can develop rapidly, complicating treatment protocols. "

01/01/2022 - "The study results indicate that there is an immediate need to monitor Campylobacter spp. in small communities of Canada and, particularly, to improve the DWDS in First Nations communities to minimize the risk of Campylobacter infection from drinking water sources. "
06/01/2017 - "The estimated waterborne disability-adjusted life year (DALY) burden for campylobacteriosis (2,004; 95% UI: 0-5,831) was 7-fold greater than other study pathogens and exceeded the WHO guidelines for drinking water quality (1 × 10-6 DALY per person per year) by 90-fold. "
02/01/1998 - "This study is first to employ molecular methods to assess the possible role of contaminated drinking water in the transmission of campylobacter infection within a dairy herd."
10/01/2023 - "Water suppliers in New Zealand have been preparing the water safety plans (WSPs) since 2005; large drinking water-associated outbreaks of campylobacteriosis occurred in Darfield in 2012 and in Havelock North in 2016. "
12/02/2022 - "A 2016 drinking water-related campylobacteriosis outbreak in Aotearoa New Zealand made much of an entire town sick leading to reforms colloquially called "Three Waters", which aims to improve the management and delivery of waste, storm and drinking water systems. "

08/01/2015 - "Quinolones have long been used as the first-line treatment for Campylobacter infections. "
06/01/2009 - "In this study, there was no evidence of more-severe or prolonged illness in participants with quinolone-resistant Campylobacter infection, nor was there evidence of any adverse medium-term consequences. "
08/12/2009 - "There is no evidence of more severe or prolonged illness in people with quinolone-resistant Campylobacter infection, nor evidence of any adverse medium-term consequences."
06/01/2009 - "This suggests that the clinical significance of quinolone resistance in Campylobacter infection may have been overestimated."
06/01/2009 - "Quinolone resistance has emerged as an increasing problem among persons with Campylobacter infection over the past decade, but the clinical consequences are unclear. "

01/01/2018 - "Rifaximin Fails to Prevent Campylobacteriosis in the Human Challenge Model: A Randomized, Double-Blind, Placebo-Controlled Trial."
01/01/2018 - "There was no difference (P = 1.0) in the frequency of campylobacteriosis in those receiving rifaximin (86.7%) or placebo (84.6%). "
01/01/2018 - "Rifaximin did not prevent campylobacteriosis in this controlled human infection model. "
02/01/2002 - "However, with the emergence of resistance, particularly in Campylobacter infection, other agents are required; interest has focused on azithromycin and rifaximin."
01/01/2021 - "The prophylactic efficacy of a twice-daily, 550 mg dose of the antibiotic rifaximin demonstrated no efficacy against campylobacteriosis in a controlled human infection model (CHIM); however, samples from the CHIM study were utilized to assess how the human gut microbiome responds to C. "

06/01/2012 - "To avoid an impact of antimicrobial drug-resistant Campylobacter spp. on the efficacy of antimicrobial treatment for human campylobacteriosis, prudent use of antimicrobial agents is a requisite. "
03/01/2022 - "Monitoring the resistance to antimicrobial agents used to treat Campylobacter infections is important in determining empiric antimicrobial treatment."
01/01/2018 - "Emerging resistance to the antimicrobial agents of choice for treatment of thermophilic Campylobacter infections is becoming a serious threat to public health. "
06/01/2012 - "The use of antimicrobial agents should be accompanied by various approaches such as prevention of Campylobacter colonization in broiler flocks with the aim of lowering the occurrence of Campylobacter infection in humans."
07/01/1996 - "These antimicrobial agents were recommended in the treatment of the campylobacterioses according to the susceptibility testing results of each isolated strain. "

01/01/2018 - "This study, including the database might be exploited for future research and the identification of effective therapeutics against campylobacteriosis. "
06/01/1988 - "Clinical trials will indicate if this compound can be used in the therapy of severe Campylobacter infections."
08/12/2016 - "During the ongoing symptomatic therapy the patient becomes gradually symptom-free 6 weeks later, resulting a total duration of symptoms caused by campylobacteriosis of 13 weeks. "
01/01/2016 - "Campylobacter infections may lead to serious conditions, including septicemia or other invasive forms of the disease, which require rapid and accurate laboratory diagnosis and subsequently appropriate antimicrobial therapy. "
11/25/2015 - "Campylobacter infections may lead to serious conditions, including septicemia or other invasive forms of the disease, which require rapid and accurate laboratory diagnosis and subsequently appropriate antimicrobial therapy. "

04/10/2000 - "Previous studies suggesting that the persistence of thermotolerant Campylobacter in water, especially as a viable but non-cultivable form (VNC), was involved in human campylobacteriosis, the capacities of survival and resuscitation of a significant collection of 85 strains in aqueous microcosms were investigated. "

09/01/1998 - "Management of enteric Campylobacter infection, therefore, is not complex and for most cases simply involves an appropriate rehydration strategy. "
01/01/2020 - "Currently, there are no vaccines approved to prevent campylobacteriosis, and rehydration is the main form of therapy. "
01/01/2017 - "Current treatment for campylobacteriosis includes rehydration and in some cases, antibiotic therapy. "

01/01/2020 - "In this review article, we will describe Campylobacter-associated disease spectrums and current treatment options, discuss the state of antibiotic resistance and alternative therapies, and provide an evaluation of various approaches that are being developed to control Campylobacter infections in animal reservoirs and the human host."
04/01/2011 - "Further investigation of this plant species may provide an alternative medicine for Campylobacter infection and an effective food additive to prevent the infection."

08/01/2000 - "Other clinical manifestations associated with Campylobacter infection included cellulitis, perinatal sepsis, peritonitis, vascular catheter-related infection, and primary bacteremia. "