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Calcitonin (Calcitonin, Eel)

A peptide hormone that lowers calcium concentration in the blood. In humans, it is released by thyroid cells and acts to decrease the formation and absorptive activity of osteoclasts. Its role in regulating plasma calcium is much greater in children and in certain diseases than in normal adults.
Also Known As:
Calcitonin, Eel; Calcitonin(1-32); Calcitrin; Ciba 47175-BA; Eel Calcitonin; Ciba 47175 BA; Ciba 47175BA; Thyrocalcitonin
Networked: 5497 relevant articles (253 outcomes, 546 trials/studies)

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Drug Context: Research Results

Experts

1. Dralle, Henning: 26 articles (01/2021 - 01/2002)
2. Machens, Andreas: 19 articles (01/2021 - 04/2005)
3. Elisei, Rossella: 18 articles (01/2022 - 01/2004)
4. Giovanella, Luca: 16 articles (11/2021 - 05/2009)
5. Dralle, H: 15 articles (12/2020 - 01/2000)
6. Miyauchi, Akira: 14 articles (01/2020 - 06/2003)
7. Niederle, Bruno: 14 articles (01/2020 - 04/2002)
8. Raue, Friedhelm: 13 articles (10/2021 - 01/2007)
9. Romei, Cristina: 12 articles (01/2021 - 01/2004)
10. Schlumberger, Martin: 12 articles (10/2019 - 01/2002)

Related Diseases

1. Osteoporosis
2. Pain (Aches)
3. Hypercalcemia (Milk Alkali Syndrome)
4. Neoplasms (Cancer)
10/01/2007 - "After Ad5-CEA-NIS-mediated NIS gene transfer in TT cell xenografts administration of a therapeutic dose of 111 MBq (3 mCi) of (131)I resulted in a significant reduction of tumor growth associated with significantly lower calcitonin serum levels in treated mice as well as improved survival. "
01/01/1990 - "Progress in the knowledge of the disease has recently been obtained in the following ways: the IRMA assay of mature calcitonin, the disease marker, has permitted earlier diagnosis of familial cases and recurrence; the locus assignment of the gene on chromosome 10 now enables a valid discrimination in certain families of gene carriers; collaborative clinical, biological, pathological, therapeutic and epidemiological research on a nation-wide scale has had a beneficial effect on patients, with improvement in diagnosis of the familial forms, in disease prognosis, in cancer detection at an infraclinical stage, and in the regrouping and distribution of families in France."
01/01/2019 - "During the study periods, the incidence increased from 0.18 to 0.25: 100,000 per year, preoperative diagnostics improved with increased use of calcitonin, ultrasound, and fine-needle cytology (p = 0.010, p < 0,001, and p = 0.001), patients were diagnosed at an earlier tumor stage (p = 0.004), and more patients were cured (p = 0.002). "
12/01/2010 - "Calcitonin determination is available, more reproducible than other specific pancreatic endocrine markers and could be effective for diagnosis and follow-up of such foregut-derived endocrine neoplasia."
12/01/1986 - "Survival results are improved if malignancy is diagnosed early from the results of plasma immunoreactive calcitonin (iCT) measurement. "
5. Neoplasm Metastasis (Metastasis)

Related Drugs and Biologics

1. Diphosphonates (Bisphosphonates)
2. Calcium
3. Steroids
4. Pamidronate (Aredia)
5. Alendronate (Alendronate Sodium)
6. Analgesics (Analgesic Drugs)
7. Glucocorticoids
8. Parathyroid Hormone (Parathormone)
9. Estrogens (Estrogen)
10. Adrenal Cortex Hormones (Corticosteroids)

Related Therapies and Procedures

1. Therapeutics
2. Thyroidectomy
3. Hormone Replacement Therapy (Therapy, Hormone Replacement)
4. Estrogen Replacement Therapy
5. Aftercare (After-Treatment)