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Caffeine (No Doz)

A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
Also Known As:
No Doz; Vivarin; 1,3,7-Trimethylxanthine; Caffedrine; Coffeinum N; Coffeinum Purrum; Dexitac; Durvitan; Percoffedrinol N; Percutaféine; Quick-Pep; Quick Pep; QuickPep; 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-
Networked: 7695 relevant articles (539 outcomes, 1390 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Wang, Hui: 33 articles (07/2022 - 01/2012)
2. Cunha, Rodrigo A: 25 articles (01/2021 - 04/2003)
3. Tsuchiya, Hiroyuki: 22 articles (02/2020 - 11/2002)
4. Chen, Jiang-Fan: 21 articles (11/2020 - 09/2002)
5. Conney, Allan H: 21 articles (01/2013 - 01/2002)
6. Doyle, Lex W: 20 articles (12/2020 - 05/2006)
7. Balkin, Thomas J: 19 articles (01/2022 - 01/2002)
8. Schwarzschild, Michael A: 19 articles (01/2021 - 09/2002)
9. Bairam, Aida: 18 articles (10/2019 - 04/2006)
10. Chen, Liaobin: 17 articles (07/2022 - 01/2012)

Related Diseases

1. Migraine Disorders (Migraine)
2. Apnea
3. Fatigue
4. Contracture
5. Pain (Aches)

Related Drugs and Biologics

1. Acetaminophen (Paracetamol)
2. Coffee
3. Analgesics (Analgesic Drugs)
4. Aspirin (Acetylsalicylic Acid)
5. Ergotamine (Ergotamine Tartrate)
6. Sumatriptan (Imigran)
7. Halothane (Fluothane)
8. Ibuprofen (Motrin)
9. Tea
10. Ephedrine

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Oral Administration
4. Bed Rest (Bedrest)
5. Artificial Respiration (Mechanical Ventilation)