|1.||Bhatia, Madhav: 22 articles (11/2015 - 10/2002)|
|2.||Konturek, S J: 22 articles (09/2008 - 01/2000)|
|3.||Zhou, Zong-Guang: 19 articles (01/2014 - 10/2002)|
|4.||Tomaszewska, R: 19 articles (10/2010 - 01/2000)|
|5.||Kim, Hyeyoung: 18 articles (12/2014 - 10/2002)|
|6.||Cuzzocrea, Salvatore: 18 articles (07/2012 - 05/2002)|
|7.||Mazzon, Emanuela: 16 articles (07/2012 - 05/2002)|
|8.||Bae, Gi-Sang: 15 articles (10/2015 - 10/2008)|
|9.||Song, Ho-Joon: 15 articles (10/2015 - 10/2008)|
|10.||Park, Sung-Joo: 15 articles (10/2015 - 10/2008)|
08/01/1991 - "Acute edematous pancreatitis was induced in rats by iv infusion of caerulein (CR) in a supramaximal dose of 7.5 x 10(-6)g x kg-1 x hr-1 during 6 hr. The most important finding of our study was the marked decrease of protein and nonprotein thiol content in pancreatic tissue of rats with CR-induced acute pancreatitis (AP). "
08/01/1998 - "The aim of this study was to test the hypothesis that apoptosis can protect against experimental pancreatitis and induction of apoptosis by an extract of Artemisia asiatica (DA-9601) is beneficial in cerulein-induced pancreatis in rats. "
10/01/2002 - "Inhibition of pancreatic ERK1/2 in vivo affords significant protection against inflammatory sequelae following cerulein-induced acute pancreatitis."
01/01/1991 - "Treatment with this agent significantly ameliorates cerulein-induced acute pancreatitis in rats. "
01/01/2003 - "Pretreatment with A2 receptors agonist seems to be protective against the damage to the pancreas during the course of caerulein-induced acute pancreatitis in rats. "
03/01/1995 - "There was less macroscopic pancreatic edema (P < 0.01) in the cerulein + TGH group than in the cerulein + saline group. "
05/01/1990 - "Pancreatic edema formation was also reduced significantly at 3.5 and 9 h after the first caerulein i.p. "
02/01/1989 - "After 3.5 h cerulein, an interstitial edema and a beginning accumulation of granulocytes in the pancreatic gland is observed. "
03/01/1986 - "Light microscopy of the pancreas in ceruletide-induced AP rats revealed marked acinar cell vacuolization and intense interstitial edema. "
05/01/1992 - "Intravenous infusion of 10 micrograms/kg.h cerulein inhibited external secretion of the pancreas from one hour and caused macroscopic edema at 3 hours. "
|3.||Exocrine Pancreatic Insufficiency
07/01/1995 - "The decrease of plasma amino acid levels in response to cerulein does not reflect pancreatic function and does not permit the diagnosis of pancreatic insufficiency."
07/01/1995 - "Cerulein-induced changes in plasma amino acid concentrations are not a valid test for pancreatic insufficiency."
01/01/1987 - "Cerulein induces hyperplasia of the pancreas in a rat model of chronic pancreatic insufficiency."
10/01/2001 - "Exocrine pancreatic insufficiency was graded, according to the results of the secretin-caerulein test, into mild, moderate and severe. "
10/01/1998 - "In coeliac disease it has been demonstrated that the indirect pancreatic function tests detect a greater percentage of subjects with exocrine pancreatic insufficiency than the secretin-caerulein test. "
03/01/2011 - "The aim of this study was to characterize lung injury in caerulein-induced AP. "
03/15/2006 - "Rats with AP-associated lung injury were induced by multiple doses of caerulein, which was demonstrated in the previous studies. "
05/01/2012 - "We therefore aimed to characterize lung injury in a clinically-relevant 'two-hit' rat model of caerulein-induced AP combined with intratracheal endotoxin. "
11/15/2011 - "Acute inhibition of NEP contributes to increased SP levels in caerulein-induced AP, which leads to augmented inflammatory responses in the pancreas and associated lung injury."
03/01/2011 - "Caerulein-induced AP results in minor lung injury, which is not sufficient to allow protein permeability and substantially alter respiratory mechanics."
03/01/2014 - "fruit extract ameliorates inflammation in the pancreas of rats subjected to alcohol and cerulein administration."
09/01/2015 - "Orthotopic inflammation-related pancreatic carcinogenesis in a wild-type mouse induced by combined application of caerulein and dimethylbenzanthracene."
02/01/2015 - "FYDR mice were exposed to cerulein, a potent inducer of pancreatic inflammation. "
06/30/2014 - "In normal mice, cerulein-mediated inflammation induced a decrease in PD2/Paf1 expression, which was later restored upon recovery of the pancreatic parenchyma. "
01/01/2014 - "This attenuated the severity of pancreatic inflammation, especially after cerulein plus LPS treatment. "
|3.||Protease Inhibitors (Protease Inhibitor)
|4.||Lipase (Acid Lipase)
|5.||Taurocholic Acid (Sodium Taurocholate)
|7.||Pancreatic Elastase (Elastase)
|3.||Induced Hyperthermia (Thermotherapy)