|1.||Fukushima, Shoji: 6 articles (06/2006 - 01/2002)|
|2.||Wanibuchi, Hideki: 6 articles (06/2006 - 01/2002)|
|3.||Endo, Ginji: 4 articles (04/2015 - 08/2002)|
|4.||Morimura, Keiichirou: 4 articles (06/2006 - 01/2002)|
|5.||Kato, Koichi: 3 articles (04/2015 - 08/2005)|
|6.||Yamanaka, Kenzo: 3 articles (04/2015 - 08/2005)|
|7.||Waalkes, Michael P: 3 articles (03/2012 - 02/2006)|
|8.||Naranmandura, Hua: 3 articles (09/2011 - 08/2007)|
|9.||An, Yan: 3 articles (11/2008 - 08/2005)|
|10.||Yoshida, Kaoru: 3 articles (02/2006 - 08/2002)|
|1.||Urinary Bladder Neoplasms (Bladder Cancer)
02/01/2015 - "Dimethylarsinic acid (DMA(V) ), the major urinary metabolite of inorganic arsenic, is a urinary bladder carcinogen and bladder tumor promoter in adult rats. "
05/01/2003 - "We hypothesize that arsenic methylation ability, defined as the ratios of monomethylarsonic acid (MMA(V))/inorganic arsenic (primary arsenic methylation index, PMI) and dimethylarsinic acid (DMA(V))/ MMA(V) (secondary arsenic methylation index, SMI), may modify the association between cumulative arsenic exposure (CAE, mg/L-year) and the risk of bladder cancer. "
09/19/2011 - "The present study was performed to gain insight into the toxicity and accumulation of arsenic species found in urine, including arsenate (iAs(V)), arsenite (iAs(III)), monomethylarsonic acid (MMA(V)), monomethylmonothioarsonic acid (MMMTA(V)), dimethylarsinic acid (DMA(V)), dimethylarsinous acid (DMA(III)), dimethylmonothioarsinic acid, (DMMTA(V)), and dimethyldithioarsinic acid (DMDTA(V)) in human bladder cancer EJ-1 cells. "
05/01/2003 - "In vitro activity of dimethylarsinic acid against human leukemia and multiple myeloma cell lines."
10/03/2006 - "In the present study we report that S-(dimethylarsino)-glutathione (DMA(III)(SG)), a putative precursor of dimethylarsinic acid DMA(V), was unstable in the culture medium without excess GSH and generated volatile substances which were highly cytotoxic for both rat heart microvascular endothelial cells and HL60, a human leukemia cell line. "
05/01/2003 - "We investigated the antiproliferative and cytotoxic activity of dimethylarsinic acid (DMAA), an organic arsenic derivative and major metabolic by-product of As(2)O(3), against a panel of eight leukemia and multiple myeloma cell lines. "
|3.||Hepatocellular Carcinoma (Hepatoma)
09/01/2005 - "In the present study, we investigated cyto-/genotoxic effects of the arsenic compounds arsenate [As(i)(V)], arsenite [As(i)(III)], monomethylarsonic acid [MMA(V)], monomethylarsonous acid [MMA(III)], dimethylarsinic acid [DMA(V)], dimethylarsinous acid [DMA(III)], and trimethylarsine oxide [TMAO(V)] after an extended exposure time (24 h) and compared the uptake capabilities of fibroblasts (CHO-9 cells: Chinese hamster ovary) used for genotoxicity studies, with those of hepatic cells (Hep G2: hepatoma cell-line). "
04/01/2015 - "Dimethylarsinic acid (DMA(V)) acted as cancer promoter promoted urinary bladder, liver, and lung carcinogenesis in rats. "
02/01/2006 - "In this regard, it was recently reported that the methylated arsenical metabolite, dimethylarsinic acid [DMA(V)], induced urinary bladder tumors in rats. "
08/14/2005 - "We investigated the relationship between lung- and skin-tumor promotion and oxidative stress caused by administration of dimethylarsinic acid (DMA(V)) in mice. "
08/01/2002 - "Carcinogenicity of dimethylarsinic acid in male F344 rats and genetic alterations in induced urinary bladder tumors."
01/01/2001 - "It was recently reported that high doses of an organic arsenical, dimethylarsinic acid (DMA), increased urinary bladder tumors in rats when administered in the diet or in the drinking water for 2 years, with the female being more sensitive than the male. "
12/01/2008 - "Hyperplasia in rats was evident by light microscopy at an earlier time point (2 weeks) than previously observed after treatment with dimethylarsinic acid (DMA(V)). "
11/01/1999 - "Dimethylarsinic acid (DMA), fed to rats for 2 years, produced bladder hyperplasia and tumors at doses of 40 and 100 p.p.m., more in females than males. "
|1.||monomethylarsonic acid (MSMA)
|3.||arsenic acid (arsenate)
|6.||Arsenicals (Arsenic Compounds)